Clinical trials: Acute Wounds
Acute Pain, Trauma
Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl
The aim of this study is to determinate the equipotent doses of inhaled metoxyflurane vs. intravenous fentanyl.
- Conditions
- Acute Pain, Trauma, Hypovolemia
- Trial name
- NCT03894800
- Testing
- Methoxyflurane (M), Fentanyl (F1), Fentanyl (F2)
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Polytrauma, Regional Anaesthesia
BLOCK-TRAUMA Study
This prospective cohort study will evaluate the association between the overall burden of regional anesthesia and early clinical outcomes in adult patients with polytrauma.
- Conditions
- Polytrauma, Regional Anaesthesia, Nerve Block, Acute Pain
- Trial name
- BLOCK-TRAUMA (NCT07702071)
- Where
- Ukraine
- Volunteers
- 500 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Sports Physical Therapy, Athletic Injuries
Acute Effects of Inspiratory Muscle Load on Diaphragmatic Recovery in Athletes
This randomized controlled trial investigates the acute effects of inspiratory muscle warm-up and fatigue on diaphragmatic function in professional basketball players.
- Conditions
- Sports Physical Therapy, Athletic Injuries, Healthy
- Trial name
- NCT07046637
- Testing
- Inspiratory muscle fatigue group, Inspiratory muscle warm-up group
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Acquired Brain Injury (Including Stroke)
Carer Involvement in Exercises for People With Acquired Brain Injury.
Increasing the amount of exercises completed has been shown to help recovery for people after a brain injury. This study will explore if providing extra training of exercises prescribed to a patient and carer team, will allow…
- Trial name
- NCT06952595
- Testing
- five exercises prescribed and taught to carers and participants
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Bulbocavernosus Reflex, Spinal Cord Injuries
Evaluation of the Bulbocavernosus Reflex After Acute Spinal Cord Injury
The purpose of this study is to evaluate the possibility to use electromyography in acute phase after a traumatic spinal cord injury to measure quantitatively and objectively the bulbocavernosus reflex.
- Trial name
- NCT04316195
- Testing
- Assessment of the bulbocavernosus reflex
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Andréane Richard-Denis
Shoulder Dislocation
Management of Acute Dislocation of Emergency in the University Hospital of Strasbourg Shoulder: Retrospective Evaluation of Practices and Proposal of a Clinical Path
The analysis of professional practices in the emergency department of the Strasbourg CHRU in the management of acute shoulder dislocations aims at proposing a clinical pathway of synthesis taking into account current practices…
- Trial name
- LuxationsHTP (NCT03154957)
- Where
- France
- Volunteers
- 238 people
- Sponsor
- University Hospital, Strasbourg, France
Perioperative Complications, Perioperative/Postoperative Complications
Perioperative Database of Chinese Elderly Patients
The investigators aim to establish a prospective database of perioperative elderly patients from multiple regions and centers. Collected data involves postoperative complications of the central nervous system, cardiovascular…
- Conditions
- Perioperative Complications, Perioperative/Postoperative Complications, Perioperative Adverse Events
- Trial name
- PDCEP (NCT04911530)
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Cardiotoxicity
Cardioprotection on Chemotherapy-Induced Cardiotoxicity
The aim of the present study is to evaluate the protective impact of cardioprotective medications on the chemotherapy- induced cardiotoxicity.
- Trial name
- NCT06853951
- Testing
- ACE Inhibitors, β -Blockers
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Kidney Injury
Acute Kidney Injury in Poly Trauma Patients
The aim of this study is to identify the incidence and the factors associated with acute kidney injury in adult poly trauma patients
- Trial name
- NCT06108765
- Volunteers
- 100 people
- Sponsor
- Assiut University
Fracture of Hip, Ileus
Peripheral Perfusion Index, Haemoglobin and Blood Transfusion in Acute Surgical Patients
The peripheral perfusion index (PPI) is a non-invasive, feasible measure of peripheral perfusion and, assumed, the overall circulation, which all patients are monitored by.
- Conditions
- Fracture of Hip, Ileus, Perforated Viscus, Anastomotic Leak
- Trial name
- NCT03795467
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Hvidovre University Hospital
Hip Fractures, Pain, Acute
Ultrasound Guided Nerve Block for Hip Fracture Pain Management at Emergency Department
The main objective is to determine if ultrasound guided suprainguinal iliac fascia block leads in better clinical outcomes such as pain management or time to home discharge.
- Conditions
- Hip Fractures, Pain, Acute, Ultrasound Therapy; Complications
- Trial name
- NCT05403073
- Testing
- Ultrasound guided Suprainguinal Iliac Fascia Nerve Block.
- Volunteers
- 72 people
- Sponsor
- Hospital San Carlos, Madrid
Acute Brain Injury
Rate of Postpyloric Migration of Spiral Nasojejunal Tubes in Brain Injured Patients
The success rate of unguided nasojejunal feeding tube insertion will be determined in acute brain injured patients. Factors influencing tube self-progression will be evaluated.
- Trial name
- NCT00562146
- Testing
- placement of spiral nasojejunal tube
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Spinal Cord Injuries, Inpatient
Exoskeletal-Assisted Walking in SCI Acute Inpatient Rehabilitation
The purpose of this research study is to test the effect of early exoskeletal-assisted walking (EAW) training (combined into regular acute inpatient rehabilitation (AIR)) on improving functional recovery and reducing pain and…
- Trial name
- NCT04221373
- Testing
- Ekso™ powered exoskeleton, Standard of care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acute Renal Failure, SIRS
BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients
The purpose of this study is to find out whether acute renal failure is associated with BK virus reactivation in postoperative/posttraumatic critically ill patients with severe SIRS/sepsis and shock.
- Conditions
- Acute Renal Failure, SIRS, Sepsis, Critically Ill
- Trial name
- BICUK (NCT00736827)
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- University of Ulm
Chest Trauma
Acute Myocardial Dysfunction and Chest Trauma - The Strainy Trauma Study
This study aims to investigate whether the identification of acute myocardial dysfunction by 2D-strain transthoracic sonography in the first week following trauma would allow to better diagnose occult and severe patterns of…
- Trial name
- Strainy trauma (NCT04748003)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Severe Thermal Injury, Greater Than 20% TBSA
Vitamin C for Severe Thermal Injuries
Animal and human data have supported the notion that administration of large doses of Vitamin C has beneficial effects on those subjects suffering from large burns.
- Trial name
- NCT01587261
- Testing
- Vitamin C
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Spinal Cord Injuries, Obesity
Effects of Intermittent Hypoxia (IH) on Metabolism and Dysglycemia, in Overweight/Obese Persons SCI
The purpose of this research is to examine changes in blood glucose control and metabolism in individuals with SCI and non injured controls at rest and during exercise after five days of exposure to IH.
- Conditions
- Spinal Cord Injuries, Obesity, Insulin Resistance
- Trial name
- NCT02973438
- Testing
- Intermittent Hypoxia (IH)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Miami
Stroke, Acute, Vessels; Occlusion
Blood Pressure Management in Stroke Following Endovascular Treatment
The aim of DETECT is to prove the feasibility of a multicenter phase III trial testing the hypothesis that intensive blood pressure control immediately after successful endovascular stroke thrombectomy can improve patient…
- Conditions
- Stroke, Acute, Vessels; Occlusion, Blood Pressure, Endovascular Thrombectomy
- Trial name
- DETECT (NCT04484350)
- Testing
- Labetalol, Hydralazine, Enalapril
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Hamilton Health Sciences Corporation
Athletic Injuries
Treatment of Complaints Following Sports Injuries With Traditional Chinese Medicine
The purpose of this observational study is to investigate the treatment of complaints following sports injuries with Traditional Chinese Medicine by therapists in Switzerland.
- Trial name
- NCT02725697
- Testing
- TCM treatment
- Where
- 3 sites in Switzerland
- Volunteers
- 2 people
- Sponsor
- Sabine Klein
Traumatic Brain Injury
Acute Intermittent Hypoxia to Improve Airway Protection in Chronic Traumatic Brain Injury
Acute intermittent hypoxia (AIH) involves 1-2min of breathing low oxygen air to stimulate neuroplasticity. Animal and human studies show that AIH improves motor function after neural injury, particularly when paired with…
- Trial name
- NCT06520358
- Testing
- Acute Intermittent Hypoxia (AIH), Task specific Airway Protection Training
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Florida