Clinical trials: Adaptation, open to volunteers
Urology, Urological Diseases
RUTISS-Diary and RUTISS-65 Study
Existing patient-reported outcome measures assess acute urinary tract infection but do not support daily symptom tracking in recurrent UTI (rUTI) or meet the needs of older adults.
- Conditions
- Urology, Urological Diseases, Patient Satisfaction, Pain, Chronic
- Trial name
- NCT07698041
- Testing
- Non-interventional Patient Reported Outcome Measure Development (RUTISS-Diary), Non-interventional Patient Reported Outcome Measure Development (RUTISS-65)
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Katherine Finlay
Aging, Supplementation
Aquatic Power Training Dosing Strategies and Creatine Supplementation in Older Adults
This randomized controlled trial will investigate the effects of different aquatic power training dosing strategies and creatine supplementation on functional and multisystem adaptations in community-dwelling older adults.
- Conditions
- Aging, Supplementation, Exercise
- Trial name
- NCT07914270
- Testing
- Time-Based Aquatic Power Training + Creatine, Sedentary Control + Creatine
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Valencia
Focus of Study: Tailored Implementation
PIECES - Towards Large-Scale Adaptation and Tailored Implementation of Primary Cancer Prevention Programs
The PIECES project aims to evaluate the Primary Cancer Prevention Implementation Toolkit (PCP-IT), an online implementation support toolkit that aids implementation teams in improving the implementation of primary cancer…
- Trial name
- PIECES (NCT06718322)
- Testing
- Primary Cancer Prevention Implementation Toolkit (PCP-IT)
- Where
- 11 sites in Albania, Australia and 7 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hidde van der Ploeg
Postpartum Depression
Postpartum 1-Day CBT Pilot Study (Türkiye)
This pilot randomized controlled trial aims to evaluate the feasibility, acceptability, and preliminary effects of a culturally adapted, one-day online Cognitive Behavioral Therapy (CBT)-based group workshop for women with…
- Trial name
- NCT07267702
- Testing
- One-Day Online CBT-Based Workshop
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Healthy Volunteers
A Technical Innovation of Prismatic Adaptation Test in Healthy Subject, in Favour of Autonomy and Independence in Daily Life Following a Brain Injury
Unilateral neglect is a neuropsychological disorder reflected by a disturbance in the spatial exploration and distribution of directed attention affecting the contralateral part of space and body relatively to the brain lesion.
- Trial name
- PRIS'TUEL (NCT03807401)
- Testing
- Prismatic goggles, Virtual reality device
- Where
- France
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Sensorineural Hearing Loss, Cochlear Implantation
Perceptual Adaptation Following Cochlear Implantation (Aim 3a)
The goal of this study is to study the adaptation process in newly implanted Single-Sided Deaf Cochlear Implant (SSD-CI) users. Subjects will use four frequency maps for the first month after CI activation.
- Conditions
- Sensorineural Hearing Loss, Cochlear Implantation, Perceptual Adaptation
- Trial name
- NCT07039435
- Testing
- Alternative Frequency Mapping
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
This phase III trial compares the effects of shorter chemotherapy (chemo)-immunotherapy without anthracyclines to usual chemo-immunotherapy for the treatment of early-stage triple negative breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8
- Trial name
- NCT05929768
- Testing
- Biospecimen Collection, Carboplatin, Cyclophosphamide
- Where
- 963 sites in United States, Mexico and 1 more
- Volunteers
- 2,400 people
- Sponsor
- SWOG Cancer Research Network
Rare Diseases, Congenital Diaphragmatic Hernia
Intact Cord Resuscitation in CDH
Isolated CDH is a rare disease (1/3500) and displays a wide range of severity and outcome. Despite attempts to standardize the management of this disease at birth and during the first months of life, the mortality varies from 20…
- Trial name
- CHIC (NCT04429750)
- Testing
- Immediate umbilical cord clamping, intact cord resuscitation
- Where
- 3 sites in France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Lille
Strength Training Adaptations, Stress
The Impact of 12-week Ashwagandha Supplementation Induced by Resistance Training on Strength, Levels of Neurotrophic and Stress Response Proteins, Oxidative and Psychological Stress, and Cognitive Function in Physically Active Male Adults
This clinical trial will study the effects of Ashwagandha (Withania somnifera), a natural plant extract, on physical and mental health in adult men.
- Conditions
- Strength Training Adaptations, Stress, Sleep Quality, Cognitive Functions
- Trial name
- NCT07803068
- Testing
- Ashwagandha, Resistance training
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Cervical Cancer Screening, Cervical Cancer
Culturally Adapted Materials to Increase Cervical Cancer Screening Among Polish Women in Iceland
This study tests whether sending Polish women residing in Iceland a culturally adapted invitation letter - tailored in language and messaging to the target group - increases participation in cervical cancer screening compared…
- Conditions
- Cervical Cancer Screening, Cervical Cancer, Cervical Cancer (Early Detection)
- Trial name
- NCT07856862
- Testing
- Culturally adapted cervical cancer screening invitation letter, Standard cervical cancer screening invitation letter
- Where
- Iceland
- Volunteers
- 2,000 people
- Sponsor
- The Primary Health Care in the Capital Area
Older People
Cross Cultural Adaptation and Psychometric Properties of Urdu Version of Fall Risk Questionnaire
Fall is an event that result a person coming to rest inadvertently on the ground or floor or other lower level. Fall and fall related injuries are very common in older population.
- Trial name
- NCT06687031
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Riphah International University
Unilateral Handgrip Dysfunction
Healthy Effects of Adapted Aikido in People With Grip Disfunction
This study investigates the effects of an adapted aikido exercise program on the health of adults with unilateral wrist and/or hand dysfunction.
- Trial name
- AdAikido (NCT07391189)
- Testing
- Participation in an adapted aikido program
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Dementia
The Black Immigrant Project
This stage I trial will examine if the culturally adapted ACES intervention affects cognitive appraisal (self-efficacy and dysfunctional thoughts) and behavioral activation with Black immigrant living with dementia and their care…
- Trial name
- NCT07546708
- Testing
- Active Caregiving: Enhancing Skills
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Minnesota
Nasopharyngeal Carcinoma by AJCC V9 Stage
Risk-Adapted Omission of Level Va Irradiation in Nasopharyngeal Carcinoma
This is a randomized, phase III, prospective, multi-center trial in newly diagnosed nasopharyngeal carcinoma (NPC) patients without distant metastasis.
- Trial name
- NCT07268690
- Testing
- Omission of Level Va Irradiation in Nasopharyngeal Carcinoma
- Where
- China
- Volunteers
- 474 people
- Sponsor
- Fujian Cancer Hospital
Caregiver Burden of People With Dementia
AIM 3 Focused Adaptation of a Mobile Caregiver Intervention for Dementia Caregivers
The goal of this clinical trial is to evaluate usability, feasibility and preliminary efficacy of a mobile telehealth supported behavioral intervention for caregivers of persons with dementia who identify as Hispanic.
- Trial name
- FAMILIA (NCT07792889)
- Testing
- Brain CareNotes Latino, Dementia Care app
- Volunteers
- 60 people
- Sponsor
- Indiana University
Child Maltreatment, Trauma, Psychological
Lighthouse Parenting Nanai: a Mentalization-based Group Therapy for Caregivers with History of Trauma
The goal of this feasibility randomized controlled trial is to evaluate the effectiveness and acceptability of the Lighthouse Mentalization-Based Treatment Parenting Program (Lighthouse MBT-P) as an intervention for parents at…
- Trial name
- NCT06889519
- Testing
- MBT Lighthouse Parenting Program, Psychoeducational cards
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University Diego Portales
Prostate Cancer
Radiation Treatment of the Prostate That is Specially Adjusted for Each Person
A number of recent studies have successfully reduced the number of radiotherapy treatments used for prostate cancer from 39 daily treatments to as little as 5 treatments.
- Trial name
- NCT07578519
- Testing
- radiotherapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- AHS Cancer Control Alberta
Breastfeeding, Breastfeeding Attitudes
Breastfeeding Education Integrated With Web Portal and Mobile Application-Supported Counseling
Breastfeeding provides significant benefits for maternal and infant health; however, perceived insufficient milk supply is one of the most common factors associated with early breastfeeding discontinuation.
- Conditions
- Breastfeeding, Breastfeeding Attitudes, Breastfeeding Education, Breastfeeding Initiation
- Trial name
- NCT07721311
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Newly Diagnosed Multiple Myeloma
Expression-linked and R-ISS-adapted Stratification for First Line Therapy in Multiple Myeloma Patients
Multiple myeloma (MM) is a malignant disease of the BM characterized by clonal expansion of plasma cells. Current guidelines recommend that newly diagnosed transplant-eligible patients with multiple myeloma (NDMMTE) shall undergo…
- Trial name
- ELIAS (NCT05665140)
- Testing
- Isatuximab, Lenalidomide, Bortezomib
- Where
- 6 sites in Germany
- Volunteers
- 100 people
- Sponsor
- University Hopsital Schleswig Holstein Campus Lübeck
Healthy Adult Participants
A Study to Test the AdaptDx Pro Agreement in Rod Intercept Time With the AdaptDx in Healthy Subjects With Normal Vision (FlashBack)
The purpose of this study is to test the AdaptDx Pro agreement in Rod Intercept (RI) time with the AdaptDx tabletop (AdaptDx) in healthy subjects with normal vision.
- Trial name
- FlashBack (NCT07803588)
- Testing
- AdaptDx Tabletop vs AdaptDx Pro
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AdaptDx, Inc.