Clinical trials: Adaptation
Aortic Valve Insufficiency, Aortic Valve Stenosis
Echocardiographic Assessment of Cardiovascular Changes in Long Term Space Flight
The National Space Biomedical Research Institute is interested in learning more about heart function in space. One potential problem with long duration, manned space flight is muscle loss- including loss of heart muscle.
- Trial name
- NCT00598598
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The Cleveland Clinic
Obesity & Overweight
Long-term Adaptations of Skeletal Muscle After Hybrid Training
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with…
- Trial name
- NCT07341711
- Testing
- Exercise training, Control group
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Depression
Internet-based Intervention Culturally Adapted for Treatment of Depression in the Ecuadorian Population
Internet-Based Interventions are increasingly relevant as an alternative for reducing the gap in treatment of metal disorders such as depression, especially in resource-limited regions.
- Trial name
- NCT04237714
- Testing
- Smiling is fun
- Where
- Ecuador
- Volunteers
- 153 people
- Sponsor
- University of Valencia
Parkinson's Disease (PD)
Adapted Physical Activity and Tango-Based Therapy for Parkinson's Disease: A Pilot Study
The purpose of this clinical research is to evaluate the effectiveness of a structured Tango-based (Riabilitango®) therapy compared to a conventional Motor Reconditioning program and a Control group in individuals diagnosed with…
- Trial name
- NCT07736014
- Testing
- Riabilitango® Tango-based program, Motor Reconditioning
- Where
- Italy
- Volunteers
- 27 people
- Sponsor
- University of Foggia
Neurofibromatosis Type 1, Von Recklinghausen Disease
Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I
This study aims to understand predictors of adaptation and quality of life among adults affected with neurofibromatosis type 1 (NF1) and autosomal dominant neurocutaneous condition.
- Conditions
- Neurofibromatosis Type 1, Von Recklinghausen Disease, NF1
- Trial name
- NCT00684398
- Where
- United States
- Volunteers
- 645 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Healthy, Healthy Participants
Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation in Adults
This experimental study investigates the acute cardiovascular and vascular responses to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Participants, Healthy Subjects (HS), Resistance Training Adaptation
- Trial name
- NCT07364149
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Probiotics
The Effect of a Multi-strain Probiotic on Acclimatization to High Altitude
The goal of this study is to learn if the probiotic SLAB51 (Sivomixx800®) works to enhance acclimatization to high altitude in humans.
- Trial name
- NCT06552806
- Testing
- SLAB51
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Cancer
Response-Adapted Omission of Nodal Boost In N3 Breast Cancer After Neoadjuvant Systemic Therapy
Background Clinical N3 (cN3) breast cancer represents a high-risk subgroup of locally advanced disease. After neoadjuvant systemic therapy (NST), patients who achieve a clinical complete response (cCR) in initially involved but…
- Trial name
- NCT07829848
- Testing
- standard boost, boost omission
- Where
- China
- Volunteers
- 534 people
- Sponsor
- Fudan University
Hemodialysis, Animal Assisted Therapy
Effects of Robotic Cat and Betta Fish Therapies in Hemodialysis Patients
The research was carried out as a randomized controlled trial to examine the physiological and psychological effects of robotic cat and Betta fish therapies in hemodialysis patients.
- Conditions
- Hemodialysis, Animal Assisted Therapy, Adaptation, Happiness
- Trial name
- Pet Therapy (NCT05339711)
- Testing
- Robotic Pet Therapy/Robot Cat Group, Pet Therapy/Betta Fish Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Karadeniz Technical University
Psychological Adaptation, Psychology, Social
Psychological Impact of the Health Measures Generated by the COVID19 in Adolescents
The lockdown of the French population is a health measure put in place in response to the pandemic linked to a new coronavirus, SARS-CoV-2 (Covid-19).
- Trial name
- COVADO (NCT04406558)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Parkinson Disease, Multiple Sclerosis
Turkish Version of Mini-BESTest, Validity and Reliability for Adult Participants With Sensoriomotor Impairments
The aim of this study is to present the Turkish version of miniBESTest which evaluates the reasons of balance deficit and postural control.
- Conditions
- Parkinson Disease, Multiple Sclerosis, Trauma, Brain
- Trial name
- NCT03839381
- Volunteers
- 50 people
- Sponsor
- Ordu University
Rare Diseases
A Longitudinal Study on Family Adaptation and Relationship Dynamics in Pediatric Rare Diseases
Rare diseases in children can affect not only the child's health but also the well-being and relationships within the entire family.
- Trial name
- FAIR (NCT07497581)
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Markus A. Landolt
Diabetes Mellitus, Type 2
Effects of Pilates Exercises Versus Walking on Mechanical and Vascular Variables of Individuals With Type 2 Diabetes Mellitus
The Diabetes Mellitus (DM) is a major worldwide public health problem. The hyperglycemia resulting from DM could lead to metabolic adaptations and physiological changes in different body systems.
- Trial name
- NCT04732611
- Testing
- Pilates exercises, Walking protocol
- Volunteers
- 60 people
- Sponsor
- Federal University of Rio Grande do Sul
Healthy Person
Visuo-Vestibular Adaptation in Virtual Reality
The vestibulo-ocular reflex (VOR) stabilizes the gaze during rapid head movements by inducing an eye rotation of equivalent amplitude but in the opposite direction to the head rotation.
- Trial name
- VIVRA (NCT06213792)
- Testing
- Adaptation of the VOR
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Hospices Civils de Lyon
Adapted Physical Activity and Cancer
Adapted Physical Activity in a Chemotherapy Ambulatory Care Unit: Feasibility and Impact on Fatigue, Anxiety and Depression in Cancer Patients
Physical activity has demonstrated efficacy in cancer prevention and improves quality of life and outcome in cancer survivors. Patients undergoing chemotherapy, especially those with advanced disease, may have symptoms leading to…
- Trial name
- UMACHAPA (NCT03049436)
- Testing
- Program of adapted physical activity
- Where
- France
- Volunteers
- 250 people
- Sponsor
- CHU de Reims
Hemodialysis Patients
The Effects of Intradialytic Aerobic Exercise on Clinical Parameters, Coping With Illness, Perceived Benefits of Exercise and Barriers to Exercise in Haemodialysis Patients: A Randomised Controlled Trial
This randomized controlled trial aims to investigate the effects of an 8-week intradialytic aerobic exercise program on clinical parameters, disease adaptation, and perceived exercise benefits and barriers in patients undergoing…
- Trial name
- NCT07758244
- Testing
- Exercise
- Volunteers
- 40 people
- Sponsor
- Muş Alparslan University
Hemodialysis, Psychosocial Adaptation
Effect of Mindfulness-based Applied to Hemodialysis Patients on Psychosocial Adaptation
The goal of this clinical study is to adapt mindfulness-based nursing interventions to hemodialysis patients and to investigate their effects on their psychosocial adjustment.
- Trial name
- EMBAHPPA (NCT06404957)
- Testing
- Mindfulness-based Applied, Active Comparator: Control groups
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Sakarya University
Melanoma of Skin
APA (Adapted Physical Activity) for Patients With Advanced Melanoma
APA (adapted physical activity) for patients with advanced melanoma APA (adapted physical activity) for patients with advanced melanoma undergoing treatment: evaluation of a personalized program at the hospital Melanoma is a…
- Trial name
- APA-M (NCT07031830)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Rouen
Coronary Artery Disease, Myocardial Revascularization
Nursing Intervention for Adaptation After Myocardial Revascularization
Introduction: Myocardial revascularization is an essential procedure for patients with cardiovascular disease. Its recovery in the outpatient setting involves significant challenges for both the patient and the caregiver.
- Conditions
- Coronary Artery Disease, Myocardial Revascularization, Postoperative Recovery After Cardiac Surgery, Nursing Care
- Trial name
- ADAPT-CABG (NCT07576569)
- Testing
- Nursing Intervention Program, Usual Care
- Where
- Colombia
- Volunteers
- 40 people
- Sponsor
- Universidad de la Sabana
HIV/AIDS, Sexually Transmitted Infection
GPS: Adaptation Trial of an HIV Prevention Counselling Program for HIV-positive and HIV-negative Gay and Bisexual Men
GPS is a sexual health promotion and HIV prevention peer-delivered counselling program. The GPS program has 4 parts: information provision about HIV and sexually transmitted infections, motivational interviewing counselling…
- Conditions
- HIV/AIDS, Sexually Transmitted Infection, Health Behavior
- Trial name
- NCT03186183
- Testing
- GPS program
- Where
- 6 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Toronto Metropolitan University