Clinical trials: Adapted Physical Activity
Multiple Sclerosis
Step it Up: An Exercise and Behaviour Change Programme for People With Multiple Sclerosis
Exercise has consistently yielded short-term, positive effects on health outcomes in people with multiple sclerosis (MS). However, these effects have not been maintained in the long-term.
- Trial name
- NCT02301442
- Testing
- Exercise + behaviour change intervention, Exercise + control education
- Where
- Ireland
- Volunteers
- 65 people
- Sponsor
- University of Limerick
Rejection; Transplant, Liver, Liver Failure
Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients
The purpose of this study is to evaluate the safety and tolerability of QEL-001 in the prevention of liver transplant rejection following immunosuppression withdrawal.
- Conditions
- Rejection; Transplant, Liver, Liver Failure, Liver Diseases
- Trial name
- LIBERATE (NCT05234190)
- Testing
- QEL-001
- Where
- 10 sites in Belgium, Spain and 1 more
- Volunteers
- 33 people
- Sponsor
- Quell Therapeutics Limited
Behavior, Intention
Incentives & Motivation for Behavior Change:
In a series of controlled, randomized experiments, we will systematically manipulate exposure to health-related messages and/or survey methods to examine the effects on behavioral intention.
- Trial name
- NCT04747327
- Testing
- mandate public, employer mandate, incentive reward
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity, Overweight and Obesity
Physical Exercise in Obesity for Health and Quality of Life.
This project aims to develop an intervention on healthy habits based on physical exercise and nutritional education in people with obesity. It is accepted that exercise and nutrition are keys to controlling body weight.
- Conditions
- Obesity, Overweight and Obesity, Overweight or Obesity
- Trial name
- OBEFYSA (NCT05713461)
- Testing
- exercise training program, Feeding training
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Pablo de Olavide
Rheumatoid Arthritis
Eccentric Exercise and Cachexia in Rheumatoid Arthritis
The purpose of the study is to determine in a randomized controlled trial (RCT), the efficacy of eccentric exercise training in restoring muscle mass and function in patients with rheumatoid cachexia.
- Trial name
- EECRA (NCT02320188)
- Testing
- Eccentric exercise, Concentric exercise
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Clermont-Ferrand
Xerostomia Following Radiotherapy, Xerostomia Following in Neck or Head After Cancer Surgery
Does Craniosacraltherapy Combined With Exercises That Focuses om Respiration and Posture in the Upper Body Have an Effect on Xerostomia and Other Late Sequelae on People Who Has Been Suffering From Cancer in Mouth and Throat?
The current study aims to assess the efficacy of manual treatment with craniosacral therapy of fascial tissue in throat, neck, cranial and mouth region, on radiation and/or surgery-induced salivary gland hypofunction and…
- Conditions
- Xerostomia Following Radiotherapy, Xerostomia Following in Neck or Head After Cancer Surgery, Other Late Sequelae Following Radiotherapy and Cancer Surgery in Neck or Head
- Trial name
- NCT05882890
- Testing
- Craniosacral Therapy, Exercices Targeting Upper Posture and Respiration
- Where
- 2 sites in Denmark
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cathrine Rahbek
Intellectual Disabilities (F70-F79), Down Syndrome (DS)
Using Technologies to Promote HEalthy Lifestyles in Adolescents With Intellectual Disabilities
IDHEApp will implement various educational technology tools and work with the families, teachers and caregivers to increase physical activity (PA) and improve healthy eating.
- Conditions
- Intellectual Disabilities (F70-F79), Down Syndrome (DS), Autism Disorder
- Trial name
- IDHEAPP (NCT07101523)
- Testing
- mHealth
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Seville
Hyperthermia
Semiconductor Heat Extraction Cooling
Heat-related injuries and other physiological stresses continue to be a significant threat to the health and operational effectiveness of the US Armed Forces (Armed Forces Health Surveillance 2011).
- Trial name
- SHE-Cool (NCT04915859)
- Testing
- Hand Cooling at 12-15 degrees celsius, Hand Cooling at 16-20 degrees celsius, hand and back cooling at 12-15 or 16-20 degrees celsius
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Sedentary, Suboptimal Health Status
Supporting Preventive Practices in Primary Care: Amplifying the Potential of Opportunistic Interventions
In France, as worldwide, the prevalence of chronic conditions is increasing, with high burden on populations and healthcare systems.
- Trial name
- APPRENDRE (NCT07391462)
- Testing
- Training for GPs to learn healthy conversation skills for supporting patients' health behavior change, No training for GP
- Where
- 4 sites in France
- Volunteers
- 882 people
- Sponsor
- Hospices Civils de Lyon
Anterior Cruciate Ligament, Injuries
Arabic Version of Marx Activity Rating and Knee Stability in Sports/Cutting-Pivoting Ability Scales
Anterior cruciate ligament (ACL) injuries are among the most common knee ligament injuries, causing joint instability and impairments.
- Trial name
- NCT05470790
- Testing
- patient reported outcome measures
- Where
- Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Onchocerciasis
Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection
Onchocerciasis is a major public health problem in affected countries that causes disease-induced disability, and overall loss of economic productivity.
- Trial name
- NCT04913610
- Testing
- ABBV-4083, Albendazole
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 153 people
- Sponsor
- AbbVie
Diabetes, Physical Activity
Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans
The goal of this clinical trial is to learn if an enhanced, culturally, socially, and structurally tailored Diabetes Prevention Program (E-DPP) can improve weight loss and related diabetes risk factors in African American adults…
- Conditions
- Diabetes, Physical Activity, Food Security, Nutrition Security
- Trial name
- NCT07560969
- Testing
- Culturally-tailored, enhanced adaption of Diabetes Prevention Program
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- University of Missouri, Kansas City
Type 2 Diabetes, Exercise
Effects of Nordic Walking and Exercise on Glucose Metabolism in Type 2 Diabetes Mellitus: A Randomized Controlled Trial
The objective of this randomized controlled trial was to evaluate the effects of two different physical exercise programs aimed at long-term lifestyle changes in physical activity in patients with Type 2 Diabetes, with glucose…
- Trial name
- NCT01085773
- Testing
- Exercise on Prescription, Nordic Walking
- Where
- Denmark
- Volunteers
- 68 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Pancreatobiliary Cancers, Pancreatic Ductal Adenocarcinoma
A Study to Assess Adverse Events and Change in Disease Activity With Treatment Combinations With Telisotuzumab Adizutecan in Adults Participants With Pancreatobiliary Cancers
Cancer is a condition where cells in a specific part of the body grow and reproduce uncontrollably. The pancreas is a gland behind the stomach that produces a digestive fluid that is emptied into the intestines through tube…
- Trial name
- NCT07769502
- Testing
- Telisotuzumab Adizutecan, Gemcitabine, Nab-Paclitaxel
- Where
- 7 sites in United States, Israel and 2 more
- Volunteers
- 168 people
- Sponsor
- AbbVie
Obesity, Diabetes Mellitus, Type 2
Stage-based Exercise Promotion Study
The purpose of this study is to increase regular physical activity among students by fostering self-management competencies. The intervention was implemented as paper-pencil intervention.
- Trial name
- STEPS (NCT01289145)
- Testing
- Motivational intervention, Volitional intervention, Active Control
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
Myopia, Obesity
Trial of a Novel Family-Based Intervention to Increase Outdoor Time and Fitness
This study aims to implement a new family-based health behavior community program to increase time spent outdoors and physical activity among Singapore children aged 6 to 12 years in a 1-year randomized clinical trial.
- Trial name
- FIT (NCT01388205)
- Testing
- Family-based Outdoor program
- Where
- Singapore
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Chest Pain
N-terminal Pro B-type Natriuretic Peptide (Nt-proBNP) Versus Exercise Test for Evaluation of Acute Chest Pain
The investigators' objective is to compare a new strategy combining clinical history and NT-proBNP levels versus the usual care, consisting of early exercise testing, for decision making in patients presenting to the emergency…
- Trial name
- NCT00493844
- Testing
- Exercise testing, Clinical evaluation + NTproBNP
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- University of Valencia
The Aim of This Study is to Evaluate the Effects of Acute Exercise on Serum Oncostatin M Levels in Healthy, Recreationally Active Males
Exercise-Induced Changes in Serum Oncostatin M Levels in Recreationally Active Males
The aim of this study was to compare the effects of workload-matched acute moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) on serum OSM levels on a cycle ergometer in recreationally…
- Trial name
- NCT07195630
- Testing
- Moderate-Intensity Continuous Exercise, High-Intensity Interval Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Subcortical Lesions, Stroke
Neuroplastic Changes Due to an Exercise Intervention That Aid in Lower Limb Recovery After Subcortical Stroke
This study aims to develop imaging-based biomarkers to assess which chronic stroke participant with lower extremity disability may respond or resist high intensity interval training (HIIT).
- Trial name
- NCT07663292
- Testing
- HIIT intervention
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Emory University
Breast Cancer, Colorectal Cancer
Assessment of Adherence to Remotely Monitored Physical Activity Tracked on a Smartwatch, and Its Impact on Reducing Fatigue 3 Months After Adjuvant Chemotherapy for Cancer
A single-center, randomized (1:1) open-label, prospective, stratified study with two parallel arms, designed to evaluate adherence to the adapted physical activity (APA) program for patients participating in an APA program and to…
- Conditions
- Breast Cancer, Colorectal Cancer, Ovarian Adenocarcinoma, Pancreatic Cancer
- Trial name
- WATCH AND ACT (NCT07429487)
- Testing
- APA program
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Centre Antoine Lacassagne