Clinical trials: Addiction, Drug
Substance Use Disorders
Efficacy of Drug and Risk Behavior Counseling Intervention Among Injecting Drug Users at Opioid Substitution Treatment
Behavior drug and risk reduction counseling (BDRC), a structured, non-intense, cognitive-behavioral approach intervention designed to increase methadone maintenance treatment retention and reduce drug use and related risk…
- Trial name
- NCT03721380
- Testing
- Treatment as usual
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Analgesic Drug Dependence, Colectomy
Opioid Free Anesthesia vs. Opioid Anesthesia Techniques.
A comparison of post-operative opioid use in Laparoscopic Colectomy patients receiving Opioid or Opioid-free Anesthesia.
- Trial name
- OFA vs OA (NCT03367988)
- Testing
- Opioid Anesthesia, Opioid-free Anesthesia
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of South Florida
Drug Addiction
Construction of Early Warning Model for the New Psychoactive Substances Using in Adolescents
Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old.
- Trial name
- NCT05958641
- Testing
- Questionnaires
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Drug Addiction
The Health of Women Monitored in the Addiction Department of the Strasbourg University Hospitals
The health of women suffering from addiction is little known and little explored in the literature. Indeed, they represent only 20% of addicted patients in general and are encountered primarily during pregnancy or complex…
- Trial name
- Santé-Fem (NCT07033728)
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Strasbourg, France
Tiletamine Use Disorder, Substance Use Disorder (SUD)
The Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation in Individuals With Tiletamine Use Disorder
Participants diagnosed with tiletamine use disorder will be assigned to active or sham taVNS for 5 days. Clinical outcomes ( e.g., behavioral paradigms measures and clinical scales ) and physiological markers (e.g., EEG and ECG)…
- Conditions
- Tiletamine Use Disorder, Substance Use Disorder (SUD), Drug Craving
- Trial name
- taVNS-Tiletami (NCT07689981)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
HIV Infection, Pain
Targeting Effective Analgesia in Clinics for HIV - Patient Cohort
The TEACH patient cohort will characterize a clinic sample of HIV-infected patients on chronic opioid therapy (COT) by describing basic demographics and health status, including characteristics of pain (severity and…
- Conditions
- HIV Infection, Pain, Drug Dependence
- Trial name
- TEACH (NCT02525731)
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- Boston Medical Center
Drug Dependency
Clinician-patient Interaction During Addiction Consultation
Accurately predicting the risk factors of patients' suffering a drug overdose plays a crucial role in effective prevention of drug overdose.
- Trial name
- CLiPID (NCT01769651)
- Testing
- methadone replacement therapy
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of St Andrews
Drug Dependence
Improving Treatment Outcomes for Prescription Opioid Dependence
Overall, this proposal seeks to improve treatment strategies for the significant public health problem of prescription opioid dependence by determining whether gabapentin, a non-narcotic pharmaceutical agent with minimal abuse…
- Trial name
- GBN (NCT02543944)
- Testing
- Gabapentin, Buprenorphine, Clonidine
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Arkansas
Substance Abuse, Substance Dependence
Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care
This component of a larger Center of Research Excellence Grant improves treatment for drug abuse by developing effective linkages between specialty drug treatment and primary health care.
- Conditions
- Substance Abuse, Substance Dependence, Substance, Addiction, Alcohol Abuse
- Trial name
- Linkage (NCT01621711)
- Testing
- Linkage patient activation intervention
- Where
- United States
- Volunteers
- 504 people
- Sponsor
- Kaiser Permanente
Drug Addiction
Effects of MDMA on Social and Emotional Processing
The main aim of the study is to investigate the effects of ±3,4-methylenedioxymethamphetamine (MDMA; ecstasy) on social and emotional processing in healthy humans.
- Trial name
- NCT01849419
- Testing
- Within-subjects (MDMA), Within-subjects (oxytocin)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Amphetamine Addiction
The Novel Addiction Assessment Study in Synthetic Drugs Addiction
The purpose of this research is to develop an objective assessment based on the virtual reality techniques which is used for evaluate addiction severity.
- Trial name
- NCT02950376
- Testing
- DSM-5 +Virtual reality-based addiction assessment system, Virtual reality-based addiction assessment system
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Opioid Addiction
Integrating Support Persons Into Recovery
INtegrated Support Persons Into Recovery (INSPIRE) is a 4-year research project that tests whether integrating a patient's support person into a patient's treatment with Buprenorphine/Naloxone can improve outcomes.
- Trial name
- INSPIRE (NCT04239235)
- Testing
- CRAFT
- Where
- 6 sites in United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Stanford University
Opioid Use Disorder
A Stepped-Wedge Cluster Randomized Trial of a Digital App to Support Medication-Assisted Treatment in Individuals With Opioid Use Disorder
The goal of this clinical trial is to learn if a mobile health app called Recovery Connect can help people stay in treatment for opioid use disorder.
- Trial name
- SMART-OUD (NCT07140926)
- Testing
- Recovery Connect
- Where
- 9 sites in United States
- Volunteers
- 1,524 people
- Sponsor
- Bright Therapeutics
Alcohol Dependence
CRF1 Antagonist GSK561679 in Alcoholism
Objective: To evaluate GSK561679, an orally available, brain penetrant selective CRH1 antagonist for its ability to reduce alcohol craving in recently detoxified alcohol dependent women in response to stress or alcohol-associated…
- Trial name
- NCT01187511
- Testing
- GSK561679
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
HIV Infections, Drug Use
INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit
The purpose of this study is to determine the efficacy of using a mobile health delivery unit ("mobile unit") to deliver "one stop" integrated health services - particularly medication for opioid use disorder (MOUD) and…
- Conditions
- HIV Infections, Drug Use, Opioid Use, Opioid-use Disorder
- Trial name
- INTEGRA (NCT04804072)
- Testing
- Medication for opioid-use disorder (MOUD) for opioid-use disorder (OUD), HIV testing, HIV treatment for participants living with HIV not already in care
- Where
- 5 sites in United States
- Volunteers
- 447 people
- Sponsor
- HIV Prevention Trials Network
Opioid Use Disorder
Light Needle for Opioid Use Disorder
This randomized-controlled study investigates the effect of adjuvant light needle in the treatment of heroin addicts. One hundred heroin addicts older than 20 years old enrolled from the Addiction Treatment Center at Kaohsiung…
- Trial name
- OUD (NCT05341219)
- Testing
- Light needle therapy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Cannabis-use Disorders
Behavioral Effects of Pregabalin and Cannabis
Cannabis is the most commonly used illicit drug in the United States, and its use is associated with rates of development of abuse and dependence, treatment admission and relapse that are comparable to other illicit drugs.
- Trial name
- NCT01511640
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joshua A. Lile, Ph.D.