Clinical trials: Addiction, Substance
Opioid Use Disorder, Opioid Use
HMP for Addictions Study
The goal of this clinical trial is to see whether the Healthy Minds Program for Addictions could be used to help veterans with moderate-severe opioid use disorder and post-traumatic stress disorder stay on buprenorphine…
- Conditions
- Opioid Use Disorder, Opioid Use, Buprenorphine Dependence
- Trial name
- NCT06063499
- Testing
- Healthy Minds Program for Addictions
- Sponsor
- University of Wisconsin, Madison
Addiction, Addiction, Alcohol
The Efficacy of a Mobile Application in Reducing Craving and Lapse Risk in Alcohol and Stimulants Problematic Use
The aim of the study is to evaluate the effectiveness of long-term and short-term app-based self-guided psychological interventions to reduce craving and lapse risk in users with substance use disorder or problematic substance…
- Conditions
- Addiction, Addiction, Alcohol, Addiction, Substance
- Trial name
- NCT05434416
- Testing
- mobile app
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- PredictWatch
Smoking Cessation, Tobacco Use Disorder
Effectiveness of Reducing Smoking in Facilitating Smoking Cessation in Adolescents - 2
Currently one in five high school students smoke. Smoking can harm adolescents well before they reach adulthood by causing a number of immediate, sometimes irreversible, health risks and problems.
- Trial name
- NCT00158158
- Testing
- Usual Care, Smoking Reduction
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Stress Disorder, Post-Traumatic, Substance-Related Disorders
Integrated Cognitive Behavioral Therapy (ICBT) for Posttraumatic Stress Disorder (PTSD) and Substance Use Disorders
The purpose of this study is to assess the safety and practicality, feasibility and efficacy of ICBT for co-occurring PTSD and substance use disorders within the OEF/OIF/OND Veterans population, as delivered by routine clinicians…
- Trial name
- NCT01457404
- Testing
- Integrated Cognitive Behavioral Therapy, Treatment-as-usual
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Nicotine Addiction, Cigarette Smoking
Control Systems Approach to Predicting Individualized Dynamics of Nicotine Cravings
Nicotine is the most common drug of abuse in the United States, and has addiction strength comparable to cocaine, heroin, and alcohol.
- Trial name
- NCT02643914
- Testing
- Nicotine, MR Compatible Nicotine Delivery Device
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Substance Related Disorder, Personality Disorders
The Impact of the Use of the MAURISSE Application in People Suffering From an Addiction.
Substance Use Disorders (SUD) are associated with cognitive schemas that lead to care attrition and mistrust towards care. Considering this, establishing a strong, trustful relationship between the patient and the healthcare team…
- Trial name
- ALMA (NCT05964296)
- Testing
- The MAURISSE application use, Usual care
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Addiction Chemical, Use, Substance
Substance Use Disorder in Chemsex Practice
The main aim of this descriptive cross-sectional study is to assess the prevalence of chemsex substance use disorder among chemsexers via an online self-questionnaire.
- Trial name
- TU CHEMSEX (NCT06476873)
- Testing
- Online self-questionnaire.
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Opioid Use Disorder
Biopsychosocial Markers of Addiction in Opioid Users: an Integrated Approach
BEBOP is a prospective, multicenter, national, comparative, non-randomized, open cohort study aiming to characterize opioid use disorder (OUD) severity and psychosocial severity among adults who use opioids, and to identify…
- Trial name
- BEBOP (NCT06021548)
- Testing
- Blood sample, Saliva sample, Hair sample
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Alcohol Dependence, Cocaine Dependence
Novel Pharmacotherapy for Dual Dependence
The purpose of this study is to evaluate the effects of Topiramate and Cognitive Behavioral Therapy for the treatment of alcohol and cocaine dependence.
- Trial name
- NCT00448825
- Testing
- Topiramate + Cognitive Behavioral Therapy
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Bankole Johnson
HIV Infection, Alcohol Use
Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort
The purpose of this study is to expand and continue a cohort of HIV-infected adults to establish the longitudinal Boston ARCH Cohort of 250 HIV-infected men and women with current substance dependence or ever injection drug use…
- Conditions
- HIV Infection, Alcohol Use, Bone Disease, Substance-Related Disorders
- Trial name
- NCT01740115
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Medical Center
Opioid-Related Disorders, Opioid Dependence
An Innovative Intervention for OUD Treatment
The Bridge Device (BD) is a neuromodulator medical device that has been cleared by the FDA for Opioid Use Disorder (OUD) treatment.
- Conditions
- Opioid-Related Disorders, Opioid Dependence, Opioid Addiction, Opioid Withdrawal
- Trial name
- Bridge (NCT04325659)
- Testing
- Bridge Device, Lofexidine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Nicotine Dependence
Do Flavors Increase the Addiction Potential of Nicotine?
The FDA has concluded that flavors (e.g. menthol) are associated with greater addiction potential in tobacco cigarettes (Gottlieb March 13, 2019).
- Trial name
- NCT04696380
- Testing
- Nicotine, JUUL e-cigarette
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Substance-related Disorders, Drug Addiction
Buprenorphine and Integrated HIV Care
The purpose of this study is to examine the efficacy of providing two levels of psychosocial support along with buprenorphine/naloxone (BUP) maintenance to opioid dependent patients receiving their care in an HIV clinical care…
- Conditions
- Substance-related Disorders, Drug Addiction, Human Immunodeficiency Virus, AIDS
- Trial name
- NCT00317460
- Testing
- Physician Management, Counseling
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Yale University
Cocaine-Related Disorders
Propranolol for Treatment of Cocaine Addiction - 2
The purpose of this study is to evaluate the safety and efficacy of propanolol in the early treatment of cocaine dependence.
- Trial name
- NCT00000197
- Testing
- Propranolol
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Opioid-use Disorder, Opioid-Related Disorders
Substance Use Treatment and Recovery Team
This study is a multi-site, randomized pragmatic trial being conducted at three diverse sites. The study, called the Substance Use Treatment and Recovery Team (START), will evaluate whether a collaborative care team increases the…
- Trial name
- START (NCT05086796)
- Testing
- Substance Use Treatment and Recovery Team (START)
- Where
- 3 sites in United States
- Volunteers
- 325 people
- Sponsor
- Cedars-Sinai Medical Center
Addiction, Depression/Anxiety
Healing Lodge First Face Training Evaluation Study
The purpose of this study is to evaluate a culturally grounded training program, xaʔtus (meaning First Face) for Mental Health. This program will train community members in how to recognize and respond to youth and adults…
- Conditions
- Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
- Trial name
- NCT06290180
- Testing
- First Face for Mental Heatlh
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Alcohol Addiction
Transcranial Magnetic Stimulation in the Treatment of Addiction
The investigators hypothesize that repetitive transcranial magnetic stimulation (rTMS) on the right side of the head will make craving towards alcohol less severe in recently detoxified alcohol addicted patients.
- Trial name
- MAGENTA (NCT01973127)
- Testing
- Verum rTMS
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- IrisZorg
Alcoholism
GSK1521498 Alcohol Interaction Study
The aim of the study is to assess the safety and tolerability of GSK1521498 in combination with alcohol and to determine the amount of GSK1521498 and alcohol in your blood after you have been given these together.
- Trial name
- NCT01366573
- Testing
- GSK1521498
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Drug Addiction
Construction of Early Warning Model for the New Psychoactive Substances Using in Adolescents
Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old.
- Trial name
- NCT05958641
- Testing
- Questionnaires
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Substance Use Disorders, Drug Abuse
CBT4CBT for Women in Residential Treatment for Substance Use Disorders
This project examines computer-delivered cognitive-behavioral intervention (CBT4CBT) as an adjunct to residential treatment for women with substance use disorders (SUD).
- Conditions
- Substance Use Disorders, Drug Abuse, Drug Addiction, Substance Abuse
- Trial name
- NCT03678051
- Testing
- Treatment as Usual (TAU), TAU+CBT4CBT
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Virginia Commonwealth University