Clinical trials: Addiction, Substance
Acute Post-operative Pain, Chronic Post Operative Pain
Duloxetine Impact on Postoperative Pain Control and Outcomes
1. Evaluate differences between patients taking Duloxetine or placebo following lateral lumbar interbody fusion for postoperative narcotic consumption. 2.
- Conditions
- Acute Post-operative Pain, Chronic Post Operative Pain, Narcotic Use, Opioid Use
- Trial name
- NCT05611749
- Testing
- Duloxetine 60 MG
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Tobacco Dependence
Improving Health for Aboriginal People Through Tobacco Related Research
Aim: To identify barriers and facilitators in the uptake of smoking cessation pharmacotherapies, tobacco prevention, doctor visits, smoking amongst youth, community held health priorities and barriers to research in Aboriginal…
- Trial name
- NCT01735448
- Testing
- Focus group, One-on-one interviews, Survey
- Where
- 3 sites in Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Queen Elizabeth Hospital
Alcohol Use Disorder
Alcohol Use Disorder Before and After Bariatric Surgery and the Impact of Considering This Surgery During Addiction Follow-up
A significant number of patients treated for alcohol use disorder have undergone bariatric surgery. Bariatric surgery is a treatment for patients suffering from morbid or severe obesity with comorbidities that can be improved by…
- Trial name
- DAACBC (NCT07273955)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Amphetamine Addiction
Novel Intervention for Amphetamine-type Stimulants Addiction
The repetitive transcranial magnetic stimulation (rTMS) will be used to treat amphetamine-type stimulant (ATS) addiction.
- Trial name
- NCT02713815
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Amphetamine Addiction
The Novel Addiction Assessment Study in Synthetic Drugs Addiction
The purpose of this research is to develop an objective assessment based on the virtual reality techniques which is used for evaluate addiction severity.
- Trial name
- NCT02950376
- Testing
- DSM-5 +Virtual reality-based addiction assessment system, Virtual reality-based addiction assessment system
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Drug Addiction, Smoking Cessation
Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3
Treatment studies have demonstrated that current smoking cessation techniques are less effective for women. The purpose of this study is to determine the role that gender plays in the effectiveness of nicotine replacement…
- Trial name
- NCT00390559
- Testing
- nicotine transdermal system, Nicotine containing cigarette
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Opioid Use Disorder
Sex and Female Empowerment
This study will develop and initially evaluate Sex and Female Empowerment (SAFE), an intervention designed to increase acceptance of and adherence to contraceptive practices among opioid-agonist-maintained women of childbearing…
- Trial name
- SAFE (NCT02197715)
- Testing
- Computer-adaptive SAFE, Face-to-face SAFE, Usual Care
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Opioid Use Disorders
mHealth to Help Pregnant and Postpartum Women in Recovery for Opioid Use Disorder
The opioid epidemic has resulted in widespread detrimental consequences among vulnerable populations in Missouri, especially among pregnant and postpartum women (PPW) with opioid use disorder (OUD).
- Trial name
- NCT06701123
- Testing
- uMAT-R mobile app with coaching component
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Washington University School of Medicine
Opioid Use Disorder, Pain
Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)
This work will involve conducting a randomized trial that will evaluate preliminary efficacy of "assisted" rate cycling, voluntary rate cycling and psychotherapy for pain individually and in combination as adjunctive treatments…
- Trial name
- EXPO-R33 (NCT05688410)
- Testing
- Exercise, Psychotherapy Pain and Addiction (I-STOP)
- Where
- 2 sites in United States
- Volunteers
- 198 people
- Sponsor
- Case Western Reserve University
Substance-Related Disorders, Drug Addiction
Family Training Program for Parents of Substance Using Adolescents
This project will modify Community Reinforcement and Family Training (CRAFT; n=15) and Alanon/Naranon Facilitation (ANF; n=15) for use with parents who are concerned about an out-of-treatment adolescent.
- Conditions
- Substance-Related Disorders, Drug Addiction, Substance Abuse
- Trial name
- FTP (NCT01344382)
- Testing
- Community Reinforcement and Family Training, Al-Anon Facilitation
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Treatment Research Institute
Opioid Use Disorders, Opioid-related Disorders
Prevalence and Predictors of Prolonged Post-surgical Opioid Use: a Prospective Observational Cohort Study
Post-surgical opioid prescribing intended for the short-term management of acute pain may lead to long-term opioid use, and its associated harms.
- Conditions
- Opioid Use Disorders, Opioid-related Disorders, Surgery, Pain, Postoperative
- Trial name
- NCT02571400
- Testing
- Continued use of opioid analgesics >90 days post-surgery
- Where
- Australia
- Volunteers
- 1,013 people
- Sponsor
- University of Notre Dame Australia
Marijuana Smoking
Nabilone & Marijuana Addiction
Safety of Nabilone in reducing marijuana craving
- Trial name
- NCT01025700
- Testing
- Cesemat
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of British Columbia
HIV Infections, Substance Use Disorders
Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care
This is a research study to assess the effectiveness of a peer-led collaborative care model for integrating treatment for substance use and or mental health disorders into HIV care settings.
- Conditions
- HIV Infections, Substance Use Disorders, Mental Health Disorder, Addiction
- Trial name
- NCT04601064
- Testing
- Collaborative Care Model
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- Johns Hopkins University
Behavior, Addictive, Adolescent - Emotional Problem
"Juego de LLaves": Study Protocol of a Universal School-based Drug Use Prevention Program (PSIDUP)
"Juego de Llaves" is a universal school-based drug prevention program for adolescents aged 12-15 years. The outcome evaluation is critical to determine the quality of preventive interventions.
- Conditions
- Behavior, Addictive, Adolescent - Emotional Problem, Alcohol Abuse, Smoking Behaviors
- Trial name
- PSIDUP (NCT05442294)
- Testing
- Juego de Llaves
- Where
- Spain
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Susana Al-Halabí
Woman Abuse, Addiction
Violence Against Women in Patients With Alcohol Substance Addiction Training
This study was planned as a randomized controlled trial in order to determine the effect of creative drama training for alcohol-substance dependent male patients on their attitudes towards violence against women.
- Conditions
- Woman Abuse, Addiction, Violence, Men
- Trial name
- NCT05595759
- Testing
- Violence against women education supported by creative drama, Routine service operation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Abant Izzet Baysal University
Mental and Behavioral Disorders Due to Use of Cocaine: Harmful Use, Opiate Addiction
Recovery Housing and Drug Abuse Treatment Outcome
Reinforcement-Based Therapy (RBT) is an intensive outpatient substance abuse treatment that includes relapse prevention skills training, goal setting, help with finding employment and abstinence-contingent rent payment for…
- Trial name
- NCT03278496
- Testing
- Recovery Housing plus Counseling, Usual Care Referral, Recovery Housing Only
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- Johns Hopkins University
Marijuana Abuse
Efficacy and Safety of the Hcoil Deep TMS for the Treatment of Cannabis Addiction
Evaluation of efficacy and safety of H-coil deep transcranial magnetic stimulation 9 week treatment trial for cannabis addiction as assessed by measures of drug intake and craving.
- Trial name
- NCT00543036
- Testing
- H-Coil deep TMS
- Where
- Israel
- Sponsor
- Shalvata Mental Health Center
PTSD, Substance Addiction
Integrated vs Sequential Treatment for PTSD and Addiction
The investigators are examining different treatment strategies of helping patients with PTSD and addiction.
- Trial name
- NCT01211106
- Testing
- Prolonged Exposure, Motivational Enhancement Therapy
- Where
- 2 sites in United States
- Volunteers
- 183 people
- Sponsor
- VA Office of Research and Development
Cigarette Smoking, Addiction
Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder
Patients in addiction treatment have exceptionally higher rate of cigarette smoking and very low quit rates compared to the general population.
- Conditions
- Cigarette Smoking, Addiction, E Cig Use
- Trial name
- NCT04063267
- Testing
- E cigarettes, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Opioid-Related Disorders, Opiate Addiction
A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire
The purpose of this study is to evaluate the patient usability and reliability of the POMAQ survey to evaluate opioid misuse and abuse among adults with chronic moderate to severe pain, including patients who are opioid abusers…
- Conditions
- Opioid-Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- POMAQ (NCT02660606)
- Testing
- Prescription Opioid Misuse and Abuse Questionnaire (POMAQ)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Member Companies of the Opioid PMR Consortium