Clinical trials: Addiction, Substance
Marijuana Abuse
Dronabinol Treatment for Marijuana Addiction
The purpose of this study is to determine if dronabinol decreases the symptoms of marijuana addiction and withdrawal.
- Trial name
- MARINOL (NCT00217971)
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Alcohol Use Disorder (AUD), Pharmacist-Patient Relations
Alcohol Telemedicine Consultation in Primary Care (ATC)
This pragmatic, cluster-randomized trial in adult primary care clinics in a healthcare system with a diverse membership will examine the effectiveness of an innovative, multi-faceted intervention, the Addiction Telemedicine…
- Conditions
- Alcohol Use Disorder (AUD), Pharmacist-Patient Relations, Alcohol Problem
- Trial name
- ATC (NCT05252221)
- Testing
- ATC Intervention
- Where
- 2 sites in United States
- Volunteers
- 41,843 people
- Sponsor
- Kaiser Permanente
Drug Addiction
The Health of Women Monitored in the Addiction Department of the Strasbourg University Hospitals
The health of women suffering from addiction is little known and little explored in the literature. Indeed, they represent only 20% of addicted patients in general and are encountered primarily during pregnancy or complex…
- Trial name
- Santé-Fem (NCT07033728)
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Strasbourg, France
Drug Addiction, Executive Dysfunction
Bilateral Prefrontal Modulation in Crack-cocaine Addiction
In this study, eligible crack-cocaine addicted inpatients recruited from specialized clinics for substance abuse disorder treatment, filling inclusion criteria and not showing any exclusion criteria, were randomized to receive…
- Trial name
- tDCS_CRACK (NCT02091167)
- Testing
- transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Federal University of Espirito Santo
Opioid-Related Disorders, Opiate Addiction
Cross-Sectional Study to Define and Validate "Doctor/Pharmacy Shopping" as Outcomes Suggestive of Abuse and/or Addiction
The purpose of this study is to formulate definitions of doctor/pharmacy shopping and evaluate its association with abuse/addiction
- Conditions
- Opioid-Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02668549
- Testing
- DB review for Doctor/Pharmacy Shopping Behavior
- Volunteers
- 164,923 people
- Sponsor
- Member Companies of the Opioid PMR Consortium
Drug Abuse
Behavioral and Subjective Efficacy of Ramelteon in Subjects With a History of Polydrug Abuse
The purpose of this study is to determine the relative abuse potential of ramelteon, once daily (QD), compared to triazolam in subjects with a history of drug abuse.
- Trial name
- NCT00671632
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Takeda
Depression, Substance Dependence
Motivational Therapy for Substance Users With Depression
The primary objective of the study is to test the incremental efficacy and outcomes of an aftercare program of Cognitive Behavioral Therapy combined with motivational therapy (CBT-MT) relative to treatment as usual (TAU) in…
- Trial name
- Aftercare (NCT01189799)
- Testing
- Motivational therapy, Dual Recovery Anonymous/Tx as usual
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of California, Los Angeles
Nicotine Addiction
Investigation of Cycloserine as a Smoking Cessation Treatment
Psychosocial treatments for drug abuse benefit some patients (Rawson et al 2004), but there is an urgent need for new treatment approaches that can improve treatment outcomes.
- Trial name
- NCT01062932
- Testing
- Cycloserine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Baylor College of Medicine
Methamphetamine, Amphetamine Dependence
Study of Medical Treatment for Methamphetamine Addiction
Currently there are no medications approved for the treatment of methamphetamine addiction. Bupropion is an antidepressant that is approved by the Food and Drug Administration (FDA) for the treatment of depression and for…
- Conditions
- Methamphetamine, Amphetamine Dependence, Pharmacogenetics, Methamphetamine Dependence
- Trial name
- BUP PGx (NCT00833443)
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of California, Los Angeles
Substance-Related Disorders, Personality Disorders
Feasibility and Acceptability Study of the "O'Dide" Application in People Suffering From an Addiction
Substance Use Disorders (SUD) are associated with cognitive schemas that lead to care attrition and mistrust towards care. Considering this within SUD management, it is important to establish a confident relation between the…
- Trial name
- FA-O'DIDE (NCT04659954)
- Testing
- Application O'DIDE
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Toulouse
Depression, Marijuana Abuse
Free Venlafaxine Treatment for Marijuana Addiction and Depression - 1
The purpose of this study is to determine if Venlafaxine Extended Release (Ven-XR) is effective in treating individuals with marijuana addiction and depression.
- Trial name
- VEN (NCT00131456)
- Testing
- Venlafaxine
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- New York State Psychiatric Institute
Nicotine Dependence, Nicotine Addiction
A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults
Almost one in ten young adults report current e-cigarette use, putting them at risk of developing nicotine addiction and long-term health effects of exposure to inhaled toxicants.
- Conditions
- Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping
- Trial name
- NCT05897242
- Testing
- Smartphone app, Text Message, Survey Administration
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Opiate Addiction
Safety Study of Intravenous 6β-Naltrexol (AIKO-150) in Opioid-Dependent Subjects
The purpose of this study is to evaluate the safety and efficacy of intravenous 6β-Naltrexol administered to opiate dependent subjects
- Trial name
- AIKO-150 (NCT00829777)
- Testing
- 6β-Naltrexol escalating doses from 0.05-0.5 mg IV
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- California Pacific Medical Center Research Institute
Substance-related Disorders, Drug Addiction
Buprenorphine and Integrated HIV Care
The purpose of this study is to examine the efficacy of providing two levels of psychosocial support along with buprenorphine/naloxone (BUP) maintenance to opioid dependent patients receiving their care in an HIV clinical care…
- Conditions
- Substance-related Disorders, Drug Addiction, Human Immunodeficiency Virus, AIDS
- Trial name
- NCT00317460
- Testing
- Physician Management, Counseling
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Yale University
Drug Addiction, Smoking Cessation
Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3
Treatment studies have demonstrated that current smoking cessation techniques are less effective for women. The purpose of this study is to determine the role that gender plays in the effectiveness of nicotine replacement…
- Trial name
- NCT00390559
- Testing
- nicotine transdermal system, Nicotine containing cigarette
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Opioid-use Disorder
Heterodyned Whole-Body Vibration in Treatment of Opioid Withdrawal-Induced Anxiety
In this randomized, double-blind, controlled, parallel group study (conducted over 12-months), enrollment is expected of up to 60 subjects (30 men and 30 women) ages 18+ who are currently going through withdrawal of OUD and being…
- Trial name
- NCT05056753
- Testing
- HWBV chair
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- PhotoPharmics, Inc.
Substance Dependence
A Human Volunteer Study Investigating Single Oral Doses of GSK598809 in Otherwise Healthy Smokers
Study to investigate the safety, tolerability and pharmacokinetics of GSK598809 in otherwise healthy volunteers. This study is required because this drug is being developed for the treatment of nicotine dependence.
- Trial name
- NCT00728052
- Testing
- GSK598809
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tobacco Use Disorder
Impact of Cigar Flavor in Dual Users
The purpose of this study is to understand addiction to filtered cigars (FCs) compared to cigarettes in young adults, ages 21-34, who smoke both cigarettes and cigars.
- Trial name
- NCT04487470
- Testing
- Flavored filtered cigars, Unflavored filtered cigars
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- UConn Health
Heroin Addiction, Relapse
PET/MRI Study on the Neurological Mechanism of rTMS Treatment for Heroin Addiction
Heroin addiction is a serious problem and the relapse rate of existing treatment methods is extremely high. Recently, international journals such as Science reported that repetitive transcranial magnetic stimulation (rTMS) can…
- Trial name
- NCT04086459
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Drug Addiction
Survey of Buprenorphine Use Among "Out of Care" Population in France (P04933)(COMPLETED)
This study was a survey of drug users who obtain buprenorphine from the black market and have used buprenorphine during the last month.
- Trial name
- NCT00756353
- Volunteers
- 600 people
- Sponsor
- Indivior Inc.