Clinical trials: Addiction, active
Substance Use Disorders, Hiv
HIV, Equity, and Addiction Training (HEAT) Program
This project is a pilot study to determine the feasibility and acceptability of a telemedicine intervention for substance use disorder service delivery in diverse people living with HIV in Alabama.
- Conditions
- Substance Use Disorders, Hiv, Opioid Use Disorder, Stimulant Use (Diagnosis)
- Trial name
- HEAT (NCT06370481)
- Testing
- Telemedicine, Standard of care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Substance Abuse, Substance Addiction
The Trans-Led Care Study
This study is testing a new mutual-help group called "the TLC program" for transgender adults who use substances or are recently in recovery.
- Conditions
- Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol)
- Trial name
- TLC (NCT06880705)
- Testing
- The TLC Program
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Illinois Institute of Technology
Opioid Abuse (Disorder), Clinical Decision Support
Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 3
This study is stage 2, round 3 of a larger study which refines and optimizes the EMBED clinical decision support (CDS) to increase number of ED physicians following standard of care for the administration of buprenorphine to…
- Trial name
- NCT07793383
- Testing
- Refined EMBED CDS, Provider alert that nurse completed COWS
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Smoking
Comparison of the Effects of Different Chest Techniques on University Students With Smoking Addiction
Smoking is a significant risk factor for heart, lung, and respiratory system diseases, and is particularly prevalent among young people and university students.
- Trial name
- NCT07488741
- Testing
- Chest PNF Techniques Group, Chest Mobility Exercises Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Internet Addiction Level, Quality of Sleep
Internet Addiction and Sleep Quality Among Medical Students
Internet addiction has become increasingly prevalent among medical students and may negatively affect sleep quality and academic performance.
- Conditions
- Internet Addiction Level, Quality of Sleep, Medical Students, Academic Performance
- Trial name
- NCT07609784
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Sohag University
Opioid Use Disorder
Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD
Despite rising rates of fatal opioid overdoses in the United States, adolescents with OUD are far less likely than adults to receive and be retained on medication for opioid use disorder (MOUD).
- Trial name
- YORS (NCT06774248)
- Testing
- Youth Opioid Recovery Support (YORS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Potomac Health Foundations
Doomscrolling, Cyberchondriac Behavior
4-STEP-Training Program for Doomscrolling, Cyberchondriac Behavior and Psychiatric Symptoms (4-STEP-TPS) Among Individuals With Social Media Addiction
The goal of this clinical trial is to evaluate the effectiveness of the 4-Step Training Program for Social Media Addiction (4-STEP-TPS) in reducing social media addiction, doomscrolling, cyberchondriac behavior, depressive…
- Conditions
- Doomscrolling, Cyberchondriac Behavior, Social Media Addiction
- Trial name
- (4-STEP-TPS) (NCT07663708)
- Testing
- 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Internet Gaming Disorder, Internet Addiction
Neurotrophic Factors, Impulsivity, and Reward Sensitivity in Children With Internet Gaming Disorder
Research and knowledge regarding the neurobiology of behavioral addictions and Internet Gaming Disorder (IGD) remain limited compared to substance and alcohol use disorders.
- Trial name
- NCT07590180
- Testing
- Clinical Evaluation and Biochemical Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Smoking ( Cigarette), Smoking (Tobacco) Addiction
Smoking Cessation With Wearables to Improve General, Oral Health and Quality of Life
Tobacco smoking remains one of the leading preventable causes of disease, disability, and premature death worldwide. According to the World Health Organization, tobacco use is responsible for more than eight million deaths each…
- Conditions
- Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation
- Trial name
- Wear-Smile (NCT07593742)
- Testing
- Telemedicine-Based Smoking Cessation Program, Conventional Smoking Cessation Behavioral Program
- Volunteers
- 102 people
- Sponsor
- University of Salerno
Dependence Addictive
Attachment and Prognostic Factor: the Implicit Approach
This is a prospective longitudinal study aimed at better understanding the determinants of the prognosis of patients with substance dependence.
- Trial name
- AIA (NCT04954027)
- Testing
- Questionnaires
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Henri Laborit
Smoking Cessation, Smoking Behaviors
ACT Lung Health Intervention: Phase Two
This study aims to test a counseling and educational program designed to improve lung health through smoking cessation for Chinese and Korean American smokers at high risk for lung cancer.
- Conditions
- Smoking Cessation, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette
- Trial name
- NCT06945120
- Testing
- ACT Lung Health Intervention
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Gambling Addiction
Testing the Interplay of Gambling, Emotion and Reward
Background The nature and direction of dysfunctional reward processing in gambling disorder remains unclear. We aim to test a novel neurobiological model of gambling addiction, that takes into account inter-individual…
- Trial name
- TIGER (NCT06122298)
- Testing
- fMRI, Ecological Momentary Assessment
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Behavior, Addictive, College Student
The Experience of Short Video Addiction Among College Students
This qualitative study aims to explore the experience of short-video addiction among college students using a directed content analysis approach grounded in the integrated framework of the Stimulus-Organism-Response (S-O-R)…
- Trial name
- NCT07574021
- Testing
- Semistructured interview
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Methamphetamine Abuse, Methamphetamine-dependence
Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users
The goal of this clinical trial is to learn if administering a high dose stimulant with Contingency Management reduces days of use in adults who use methamphetamine better than the usual treatment provided by the clinic.
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance, Addiction
- Trial name
- NCT05854667
- Testing
- Treatment as Usual plus lisdexamfetamine (LDX-01), Treatment as Usual plus lisdexamfetamine (LDX-01) plus Contingency Management
- Where
- 4 sites in Canada
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Substance Use Disorders, Posttraumatic Stress Disorder
Written Exposure Therapy for Veterans With SUD and PTSD
The proposed project will evaluate the efficacy of written exposure therapy (WET) among Veterans engaged in substance use disorder (SUD) treatment, who present with co-occurring posttraumatic stress disorder (PTSD).
- Trial name
- WET (NCT05327504)
- Testing
- Written Exposure Therapy, Neutral Topic Writing
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Smoking, Nicotine
Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking
Tobacco use is the leading cause of preventable death in the U.S., with 480,000 deaths per year and 7.7 million deaths globally.
- Conditions
- Smoking, Nicotine, Tobacco, Addiction
- Trial name
- NCT07328594
- Testing
- Daridorexant 50 mg
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Legacy Health System
Methamphetamine Use Disorder
Psilocybin for Methamphetamine Addiction
The primary purpose of this study is to preliminarily determine if the use of psilocybin to promote abstinence from methamphetamine is feasible and well tolerated in populations such as those found in Northern Louisiana.
- Trial name
- NCT06899594
- Testing
- Psilocybin 25 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kevin Murnane
Cannabis Use, Cannabis Dependence
Neuroimaging of Adolescent Cannabis Use Treatment
This study is testing whether brain activity related to learning can help predict how well teens respond to a treatment program designed to reduce cannabis use.
- Conditions
- Cannabis Use, Cannabis Dependence, Cannabis Use Disorder, Cannabis Abuse
- Trial name
- ACT (NCT07340554)
- Testing
- Contingency Management, Elastic Net Regression
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Indiana University
Alcohol Drinking, Cannabis Use
Cannabis' Impact on Alcohol Consumption
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which…
- Conditions
- Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder
- Trial name
- NCT05389930
- Testing
- THC-dominant cannabis, CBD-dominant cannabis, Alcohol
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Brown University
Opioid Use Disorder, Major Depressive Disorder (MDD)
Helping Kentuckians Overcome Depression and Opioid Addiction With Brain Stimulation
This study will compare transcranial magnetic stimulation (TMS) with sham TMS in people with opioid use disorder who are taking buprenorphine and have major depressive disorder with ongoing depressive symptoms.
- Trial name
- NCT07842601
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Kentucky