Clinical trials: Addiction Nicotine, open to volunteers
Smoking Addiction
Evaluation of the Effectiveness of Routine Nurse Education in Prescribing Nicotine Replacement Therapy for Hospitalized Smokers in a University Hospital
The goal of this study is to determine whether training nurses to prescribe nicotine replacement therapy (NRT) can increase the proportion of smoking cessation at one month after hospital discharge among active smokers (daily or…
- Trial name
- NICOTINURSE (NCT06789536)
- Testing
- training nurses to prescribe nicotine substitutes, to adapt doses and to transmit to the outpatient physician and/or nurse nurse to facilitate the continuation of treatment
- Where
- 4 sites in France
- Volunteers
- 442 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nicotine Dependence
Effects of Psilocybin on Craving in Nicotine Dependence
This pilot study will examine how a single 25 mg dose of psilocybin affects nicotine craving in people with nicotine dependence.
- Trial name
- SCANS-PSIL (NCT07852832)
- Testing
- Psilocybin (drug)
- Volunteers
- 3 people
- Sponsor
- University of British Columbia
Behavioral Intervention, Nicotine Addiction
Impact of Appointment Reminder Strategies on Smoking Cessation Clinic Attendance
The goal of this clinical trial is to learn whether different appointment reminder methods can improve attendance at an anti-smoking (smoking cessation) clinic among adult smokers.
- Trial name
- NO-SHOW-NCC (NCT07779161)
- Testing
- Standard phone call, phone call with MINDSPACE elements
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Gdansk
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from F8 coil or active rTMS from H coil for smoking cessation.
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT05276050
- Testing
- active F8-coil delivered rTMS, active H-coil delivered rTMS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston
Community Health Services, Respiratory Disease
INSPIRE Respiratory Health Program in Botucatu, São Paulo, Brazil
The goal of this observational study is to evaluate the implementation of the INSPIRE program and to plan actions for the preparation, coordination, monitoring, diagnosis, and treatment of respiratory diseases in the municipality…
- Conditions
- Community Health Services, Respiratory Disease, Tobacco Smoking
- Trial name
- NCT06673225
- Testing
- Analysis of results
- Where
- Brazil
- Volunteers
- 2,000 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Vaping, Vaping Cessation
Social Media Support Groups for Adolescent Vaping Cessation
The purpose of this study is to pilot test feasibility and acceptability of the Quit the Hit Toolkit, a social media-based nicotine vaping cessation program for adolescents and young adults, adapted for use in community settings.
- Conditions
- Vaping, Vaping Cessation, Nicotine Dependence
- Trial name
- NCT07540780
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nicotine Dependence, Tobacco Smoking
Smoking Cessation and Menstrual Cycle Phase
Tobacco use is a risk factor for at least 20 types of cancer and remains the leading preventable cause of cancer in Canada. Smoking cessation is an important cancer prevention strategy for the close to 2 million Canadian women…
- Conditions
- Nicotine Dependence, Tobacco Smoking, Smoking Cessation, Nicotine Use Disorder
- Trial name
- MC-NRT (NCT05515354)
- Testing
- Timing of nicotine replacement therapy start date, Nicotine Replacement Therapy Agent
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Use Disorder
Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation
The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers.
- Trial name
- NCT05726045
- Testing
- Standard smoking cessation program (SCP), Cognitive remediation treatment (CRT), High-intensity interval training (HIIT evening)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Nicotine Addiction
Non-Invasive Deep Brain Neuromodulation for Smoking Cessation
This study will develop novel low intensity focused ultrasound (LIFU) therapy to help people to quit cigarette smoking. Smoking is associated with cancers of the lung. Available smoking cessation methods help many to quit.
- Trial name
- NCT07298902
- Testing
- Low intensity focused ultrasound with active stimulations
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention
A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school…
- Conditions
- E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
- Trial name
- NCT07460622
- Testing
- Virtual Reality E-Cigarette Prevention Program
- Where
- United States
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- Yale University
Nicotine Dependence, Cigarettes, Nicotine Withdrawal
The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments
The INITIATE Study is a randomized controlled trial that is testing an intervention designed to increase long-term abstinence among tobacco smokers seen in emergency departments (ED) and other high-volume hospital and community…
- Trial name
- INITIATE (NCT04163081)
- Testing
- Quit Card Intervention (QCI)
- Where
- 4 sites in Canada
- Volunteers
- 1,208 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Nicotine Dependence, Tobacco-Related Carcinoma
A Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette Users
This clinical trial evaluates a smartphone application (app) called Acceptance and Commitment Therapy (ACT) on Vaping for helping young adults quit using electronic cigarettes (e-cigarettes).
- Trial name
- NCT06909500
- Testing
- Smartphone app, Text Message, Survey Administration
- Where
- United States
- Volunteers
- 1,178 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
E-cigarette Use, Vaping
A Trial of Varenicline for E-cigarette Cessation
This is randomized, placebo-controlled clinical trial in treatment-seeking adults who report regular e-cigarette use to test the hypothesis that varenicline is efficacious for quitting e-cigarettes.
- Conditions
- E-cigarette Use, Vaping, Nicotine Dependence
- Trial name
- NCT07040566
- Testing
- Varenicline 1mg BID
- Where
- 2 sites in United States
- Volunteers
- 326 people
- Sponsor
- Yale University
Nicotine Dependence, E-cigarette Use
Sex Differences in E-Cigarette Perception
This study examines differences between males and females in the appeal and addiction potential of menthol flavored e-cigarettes with and without nicotine.
- Trial name
- NCT07398976
- Testing
- Nicotine Level 1 (0mg/ml), Nicotine Level 2 (36mg/ml), Nicotine Level 3 (59mg/ml)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Cigarette Smoking, Nicotine Dependence
Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
Tobacco-free oral nicotine pouches (such as Zyn brand) are a less harmful alternative to cigarette smoking. Pouches, however, contain nicotine, and addictive substance that is not risk-free.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Smoking Cessation
- Trial name
- Pack2Pouch (NCT06678789)
- Testing
- High Nicotine Dose, Low Nicotine Dose
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina