Clinical trials: Adenomyosis
Adenomyosis
Adenomyosis Patients With Infertility and Immunological Factors
Infertile patients with adenomyosis who met the inclusion and exclusion criteria, after signing the informed consent form, the researchers recorded the clinical information of the patients and initiated the in vitro…
- Trial name
- NCT06123975
- Testing
- Venous blood collection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Fibroid, Adenomyosis
Oxytocin in MRI-HIFU
Capability of oxytocin in improving the efficacy of MRI-HIFU is studied. Patients undergoing MRI-HIFU treatment are given oxytocin during treatment and the efficacy of the treatment will be analysed by patient reported symptom…
- Trial name
- NCT03937401
- Testing
- Oxytocin
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Adenomyosis, Endometriosis
A Multi-omics Study of Adenomyosis
This study aims to analyze the multi-omics results between eutopic endometrium, adenomyosis and endometriosis of patients diagnosed of adenomyosis with and without endometriosis.
- Conditions
- Adenomyosis, Endometriosis, Ectopic Endometrium, Eutopic Endometrium
- Trial name
- NCT03742843
- Testing
- A multi-omics analysis
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Lei Li
Abnormal Uterine Bleeding
Management of Uterine Leiomyomata and Adenomyosis
1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination 2.
- Trial name
- NCT05153928
- Testing
- Norethisterone acetate
- Where
- 2 sites in Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ahmed Ali Mahmoud
Adenomyosis of Uterus
Evaluation of the Efficacy and Safety of Microwave Ablation of Uterine Adenomyosis Under Improved Ultrasound Guidance
This study aims to compare the safety and efficacy of segmental power adjustment combined with uterine cavity hydro-isolation in microwave ablation of adenomyosis
- Trial name
- NCT06751264
- Testing
- Peritoneal combined with intrauterine water isolation, Peritoneal water isolation
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Peking University Aerospace Center Hospital
Uterine Myoma, Adenomyosis
Use of Dexamethasone in Uterine Artery Embolization
The primary purpose of this study is to investigate the effects of dexamethasone on inflammatory reactions after uterine artery embolization.
- Trial name
- NCT02056717
- Testing
- Dexamethasone, Normal saline
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Severance Hospital
Pelvic Organ Prolapse, Gynecologic Cancers
Electronic Catheter Stethoscope
This is an observational, exploratory study designed to collect (record) and analyze normal and abnormal sound data from the human bladder during surgery using a novel sensor-based catheter system (Electronic Catheter…
- Conditions
- Pelvic Organ Prolapse, Gynecologic Cancers, Uterine Leiomyomata, Adenomyosis
- Trial name
- NCT01463462
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of South Florida
Adenomyosis, Endometrial Cancer
Multi-omics Study on the Pathogenesis of Malignant Transformation of Adenomyosis
This study is to explore the driving genes and the molecular mechanism of malignant transformation of adenomyosis. This study acquired the formalin fixed paraffin-embedded (FFPE) tissue of patients pathologically conformed…
- Conditions
- Adenomyosis, Endometrial Cancer, Ectopic Endometrial Tissue, Eutopic Endometrium
- Trial name
- NCT04010487
- Testing
- whole exome sequencing and RNA-sequencing
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Lei Li
Adenomyosis
A Prospective Study of Diagnostic Accuracy of Ultrasound
Prospectively-Patients undergoing a hysterectomy for abnormal uterine bleeding (AUB) or pelvic pain will be enrolled in the study, will get pelvic ultrasound at the ultrasound clinic.
- Trial name
- NCT03120078
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Pelvic Pain Associated With Endometriosis or Adenomyosis, Pelvic Pain Associated With Refractory Endometriosis
Efficacy and Tolerability of TENS in Endometriosis-related Pain
ELECTRE is a single-center, randomized, prospective, longitudinal, controlled, two-arm, single-blind study lasting 4 weeks (P1 investigation phase) after a 4-week run-in period.
- Conditions
- Pelvic Pain Associated With Endometriosis or Adenomyosis, Pelvic Pain Associated With Refractory Endometriosis, Endometriosis
- Trial name
- ELECTRE (NCT07393295)
- Testing
- Conventional TENS, Microstimulation TENS
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Monath Electronic
Adenomyosis
FET in Adenomyosis
Purpose of the Study: To compare the effectiveness of GnRH agonist downregulation alone versus GnRH agonist combined with letrozole in improving pregnancy outcomes in women with adenomyosis undergoing frozen embryo transfer…
- Trial name
- ADY (NCT06913075)
- Testing
- GnRH agonist downregulation, GnRH agonist and Letrozole
- Where
- India
- Volunteers
- 700 people
- Sponsor
- Indira IVF Hospital Pvt Ltd
Adenomyosis
Accuracy of Endomyometrial Biopsy in Diagnosis of Adenomyosis
This study will compare the accuracy of diagnosing adenomyosis by obtaining hysteroscopic guided endomyometrial biopsy and comparing it to accuracy of diagnosis by transvaginal ultrasound and magnetic resonance imaging.
- Trial name
- NCT05505656
- Testing
- hysteroscopic guided endomyometrial biopsy
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Adenomyosis
Ttt of Adenomyosis
to evaluate use of Dienogest versus uterine arteries embolization in treatment of Adenomyosis-associated symptoms as dysmenorrhea, heavy menstrual bleeding and bulk-related symptoms
- Trial name
- NCT06719934
- Testing
- Dienogest 2 mg orally, UAE
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Adenomyosis
Norwegian Adenomyosis Study II: Gene Expression Profiling of Adenomyosis
Adenomyosis is characterized by the appearance of endometrial cells in the muscular layer of the uterus. It affects about 15-20% of the female population.
- Trial name
- NAPPED II (NCT02197923)
- Testing
- Myometrial biopsy, endometrial biopsy
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Indications for Laparoscopic Supracervical Hysterectomy
Use of the Enseal Intrument for Laparoscopic Supracervical Hysterectomy
The use of the EnSeal® instrument for laparoscopic supracervical hysterectomy in a randomized, single-blinded comparison to the conventional procedure.
- Trial name
- NCT01806012
- Testing
- Sealing tissue with the Enseal device, Conventional supracervical hysterectomy
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- University Hospital Tuebingen
Endometriosis
Quinagolide Vaginal Ring on Lesion Reduction Assessed by MRI in Women With Endometriosis/Adenomyosis
This will be a randomized, double-blind, placebo-controlled, proof-of-mechanism phase 2 trial investigating the effect of quinagolide extended-release vaginal ring on reduction of lesions assessed by high-resolution magnetic…
- Trial name
- QLARITY (NCT03749109)
- Testing
- Quinagolide 1080 µg
- Where
- 11 sites in Denmark, Germany and 2 more
- Volunteers
- 67 people
- Sponsor
- Ferring Pharmaceuticals
Adenomyosis
Adenomyosis and Ulipristal Acetate
Evaluation of efficiency of selective progesterone receptor modulators (SPRM) (Ulipristal acetate) on bleeding control and pain for patients with adenomyosis and wish to keep fertility.
- Trial name
- FRA-IIT-UPA (NCT02587000)
- Testing
- Ulipristal acetate
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endometriosis, Adenomyosis of Uterus
Artificial Intelligence Into Ultrasound Diagnostics in Reproductive Medicine
The goal of this observational study is to develop and validate artificial intelligence (AI)-based algorithms that support ultrasound diagnosis of endometriosis, adenomyosis, myometrial masses, uterine malformations, and impaired…
- Conditions
- Endometriosis, Adenomyosis of Uterus, Leiomyoma (Uterine Fibroids), Uterine Neoplasms
- Trial name
- AUDRIE (NCT07810920)
- Where
- Hungary
- Volunteers
- 1,600 people
- Sponsor
- Semmelweis University
Adenomyosis
GyneFix IUD Plus LNG-IUS for Adenomyosis
Adenomyosis is a common gynecological condition that can cause menstrual pain, heavy menstrual bleeding, anemia, and reduced quality of life.
- Trial name
- GYNEFIX-AM (NCT07680985)
- Testing
- Indomethacin-GyneFix IUD Plus LNG-IUS, Ring IUD Plus LNG-IUS, LNG-IUS Alone
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Wenzhou People's Hospital
Adenomyosis
Levonorgestrel-releasing Intrauterine System for the Treatment of Symptomatic Adenomyosis
Objective: To investigate the effects of levonorgestrel-releasing intrauterine system (LNG-IUS) for symptomatic adenomyosis. Methods: From December, 2006 to December, 2014, symptomatic patients of adenomyosis diagnosed (with…
- Trial name
- NCT03027648
- Testing
- Placement of levonorgestrel-releasing intrauterine system
- Volunteers
- 1,100 people
- Sponsor
- Peking Union Medical College Hospital