Clinical trials: Adenomyosis
Myoma;Uterus, Adenomyosis of Uterus
RCT - Efficacy of Intravenous Vitamin C Versus Placebo on Estimated Blood Loss in Total Abdominal Hysterectomy
Intervention Group: Received two 1 gm doses of Vitamin C intravenously (IV). first Dose: At midnight on the day of surgery. Second Dose: Immediately after the surgical incision.
- Trial name
- Vit C in TAH (NCT07335432)
- Testing
- Vitamin C (Ascorbic Acid)
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Elective Fertility Preservation
Study of the Prevalence of Endometriosis and Adenomyosis
Our study aims to assess the prevalence of adenomyosis and endometriosis in patients consulting for elective fertility preservation through the diagnosis of these pathologies by transvaginal pelvic ultrasound.
- Trial name
- PrevADEOSE (NCT06211569)
- Testing
- Usual follow-up
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease
The Learning Curve of a Gynecology and Obstetrics Resident Performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) Hysterectomy in a University Hospital
This prospective observational study aims to evaluate the learning curve of obstetrics and gynecology residents performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) hysterectomy in a university hospital…
- Conditions
- Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease, Adenomyosis of Uterus, Uterine Leiomyomas
- Trial name
- LC of V-NOTES (NCT07465822)
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Cukurova University
Endometriosis
Efficacy of Trace Elements in the Treatment of Endometriosis: a Pilot Study
The primary objective of this pilot study is to evaluate the efficacy of trace elements, versus placebo, on the reduction of pain in endometriosis of an American Fertility Society (AFSr) score of 2 to 4, combined or not to an…
- Trial name
- NCT02437175
- Testing
- ENDO 1/ENDO 2
- Where
- Belgium
- Volunteers
- 99 people
- Sponsor
- Laboratoires Pronutri
Cervical Cancer, Ovarian Tumor
The Application of Real-Time Near-infrared Imaging in Gynecological Surgery
Removing in situ and metastasis lesions completely during gynecological surgery is central to reduce the recurrence and death, and the identification of lesions in traditional gynecological surgery often depends on the experience…
- Conditions
- Cervical Cancer, Ovarian Tumor, Endometrial Carcinoma, Uterine Myomatosis
- Trial name
- NCT04224467
- Testing
- Intravenous ICG and Real-Time Near-infrared Imaging
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chen Chunlin
Symptomatic Uterine Fibroids and Adenomyosis
Effectiveness of IV Acetaminophen and IV Ibuprofen in Reducing Post Procedural Pain in the UFE Procedure
The uterine fibroid embolization (UFE) procedure is a treatment option for abnormal heavy menstrual bleeding and/or bulk symptoms associated with uterine fibroids and adenomyosis.
- Trial name
- NCT02227316
- Testing
- IV Ibuprofen, IV Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of California, Los Angeles
Adenomyosis of Uterus
Aspirin in the Treatment of Pregnant Women With Adenomyosis on Reducing Preterm Delivery
Objective: This study intends to carry out a randomized double-blind clinical trial study of aspirin in the treatment of pregnancy with adenomyosis to reduce the incidence of preterm delivery, and provide a new therapeutic target…
- Trial name
- NCT04535804
- Volunteers
- 550 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Endometriosis, Adenomyosis
Comparison of the Operation and Medical Treatment of Endometriosis and Adenomyosis
Endometriosis (including adenomyosis) is one of the most common gynecological diseases among women of childbearing age. Common symptoms such as menstrual pain, excessive menstrual flow, infertility, chronic lower abdominal pain…
- Trial name
- NCT03778359
- Testing
- Leuprorelin, Levonorgestrel, Dienogest
- Where
- Taiwan
- Volunteers
- 5,000 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Endometriosis
Progestin Treatment for Endometrial Stromal Cells in Adenomyosis
Long term treatment of progestin has been demonstrated to have an inhibitory effect on endometrial angiogenesis and the proliferation of endometrial stromal cells.
- Trial name
- NCT00155051
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Endometriosis, Adenomyosis
Assessing the Mechanisms and Impact of a Novel Cannabinoid Product for Gynecologic Pain
Despite recent increases in both medical and recreational cannabis use in the United States and globally, little research has been conducted to determine the potential applications for womens health.
- Conditions
- Endometriosis, Adenomyosis, Chronic Pelvic Inflammatory Disease
- Trial name
- PAIN-GP (NCT07728695)
- Testing
- Custom-formulated, high-CBD study product
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Staci Gruber, Ph.D.
Cholecystitis, Cholecystolithiasis
Drainage or Not for Laparoscopic Cholecystetomy
Surgeons usually choosing drainage tube for laparoscopic cholecystectomy according to their experiences but not guidelines. The investigators design a RCT to evaluate the role of drainage in LC surgery and compare the clinical…
- Conditions
- Cholecystitis, Cholecystolithiasis, Polyps Gallbladder, Adenomyosis of Gallbladder
- Trial name
- NCT03909360
- Testing
- drainage tube
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Endometriosis
Evaluation of Endometrial Stromal Cell Apoptosis in Adenomyosis
Our previous results revealed that the expression of killer inhibitory receptors (KIRs) on NK cells was decreased in eutopic endometrium in women with adenomyosis.
- Trial name
- NCT00172588
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Internal Endometriosis
Study of Diphereline 3.75 mg Treatment In Women Suffering From Internal Genital Endometriosis
To describe Gonadotropin-Releasing Hormone agonists (GnRH-a) treatment effectiveness on reduction of internal genital endometriosis symptom - menorrhagia - in different disease stages I, II, III in the Russian patient population…
- Trial name
- NCT03586063
- Testing
- Data collection
- Where
- 34 sites in Russia
- Volunteers
- 465 people
- Sponsor
- Ipsen
Endometriosis, Adenomyosis
Benefit of GnRH Agonist Before Frozen Embryo Transfer in Patients With Endometriosis and/or Adenomyosis
Women suffering from endometriosis and/or adenomyosis may also suffer from infertility. GnRH agonist injection could improve implantation and therefore increase the pregnancy rate in these patients.
- Conditions
- Endometriosis, Adenomyosis, Infertility, Female
- Trial name
- DECATEC (NCT04356664)
- Testing
- GnRH agonist
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Hopital Foch
Adenomyosis
Radiofrequency Ablation of Adenomyosis
To observe the effects of radiofrequency ablation on adenomyosis through the pathological analysis of treated tissue that has been removed during planned hysterectomy.
- Trial name
- NCT05130190
- Testing
- RF Treatment
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Texas Southwestern Medical Center
Adenomyosis
Role of Uterine Artery Embolization in Adenomyosis
Management of symptomatizing women diagnosed with uterine adenomyosis, by uterine artery angioembolization as a minimally invasive replacement for hysterectomy.
- Trial name
- NCT05597644
- Testing
- Trans-arterial uterine artery embolization
- Volunteers
- 30 people
- Sponsor
- Assiut University
Endometriosis, Adenomyosis
Development and Validation of EHP-30 (Hong Kong Chinese Version) for Patients With Endometriosis and Adenomyosis
Endometriosis and adenomyosis can impact on the quality of life including the physical, psychological and social aspects. It is important to include quality of life measurements in evaluating the disease severity and response to…
- Trial name
- NCT03302468
- Where
- Hong Kong
- Volunteers
- 448 people
- Sponsor
- Chinese University of Hong Kong
Adenomyosis, in Vitro Fertilization
Cohort Profile：The Shandong Adenomyosis Cohort of Population Undergoing Reproductive Technology (SAart)
Previous studies have shown that compared with infertile women without adenomyosis, the clinical pregnancy rate, live birth rate and continuous pregnancy rate of women with adenomyosis significantly reduce, and the abortion rate…
- Trial name
- NCT06604091
- Testing
- Treatment protocol
- Where
- China
- Volunteers
- 2,241 people
- Sponsor
- The Second Hospital of Shandong University
Adenomyosis
Adenomyosis and ART
The goal of this clinical trial is to: Prospectively investigate the association of Adenomyosis with fertility outcomes in relation to COH protocols for ART (long or ultra- long protocol) with a preventive high-dose…
- Trial name
- ADENOFERT (NCT05937490)
- Testing
- Enantone, Dienogest 2 MG (milligram), long GnRH agonist or flexible GnRH antagonist protocol.
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Adenomyosis
Levonorgestrel Intrauterine System and Adenomyosis
Adenomyosis is defined when the endometrial tissue (gland and stroma) is present within the myometrium . The depth of endometrial penetration which uses in diagnosis of adenomyosis not yet agreed; opinions range from one high…
- Trial name
- NCT03104309
- Testing
- Levonorgestrel intrauterine system
- Volunteers
- 100 people
- Sponsor
- Assiut University