Clinical trials: Adenomyosis of Uterus
Recurrent Implantation Failure, Recurrent Pregnancy Loss
Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss
The IMERR study aims to improve understanding of certain causes of infertility related to recurrent implantation failure (RIF) and/or recurrent pregnancy loss (RPL), conditions that affect many women undergoing assisted…
- Conditions
- Recurrent Implantation Failure, Recurrent Pregnancy Loss, Infertility, Female, Endometrial Diseases
- Trial name
- IMERR (NCT07265505)
- Testing
- Endometrial Biopsy, Vaginal Swab, Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adenomyosis
Modified Downregulation for Women With Adenomyosis of the Uterus Prior to Frozen-thawed Embryo Transfer.
1 in 7 couples experience difficulty in conceiving. Many will require in vitro fertilization (IVF). IVF involves an initial period of downregulation to suppress the ovaries and prevent premature ovulation.
- Trial name
- MODA (NCT03946722)
- Testing
- GnRH analogue downregulation, Participant questionnaire
- Where
- United Kingdom
- Volunteers
- 162 people
- Sponsor
- University College, London
Adenomyosis of Uterus
Aspirin in the Treatment of Pregnant Women With Adenomyosis on Reducing Preterm Delivery
Objective: This study intends to carry out a randomized double-blind clinical trial study of aspirin in the treatment of pregnancy with adenomyosis to reduce the incidence of preterm delivery, and provide a new therapeutic target…
- Trial name
- NCT04535804
- Volunteers
- 550 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Endometriosis, Adenomyosis
Clinical and Molecular Study of Endometriosis and Adenomyosis
The purpose of this study is to determine whether endometriosis and adenomyosis are progressive diseases, in terms of symptoms (pain, abnormal uterine bleeding and infertility), anatomical lesions size, and recurrences.
- Trial name
- ENDOCHAP (NCT04481321)
- Testing
- Biological/Vaccine
- Where
- France
- Volunteers
- 5,300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endometriosis, Adenomyosis
Pain in Endometriosis And the Relation to Lifestyle
The goal of this clinical trial is to investigate the effect of an anti-inflammatory diet and cognitive behavioral therapy (CBT) on pain symptoms, health related quality of life and the effect on inflammatory characteristics in…
- Trial name
- PEARL (NCT06332560)
- Testing
- Anti-inflammatory diet (DI), Cognitive behavioral therapy (CBT)
- Where
- 5 sites in Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Pelvis Pain Chronic, Endometriosis of Uterus
Functional Brain Imaging and Psychological Testing in Women With Chronic Pelvic Pain
Functional magnetic resonance imaging in women with chronic pelvic pain using arterial spin labelling, functional connectivity, diffusion tensor imaging and magnetic resonance spectroscopy.
- Trial name
- NCT02160483
- Testing
- Functional magnetic resonance imaging
- Where
- Singapore
- Sponsor
- KK Women's and Children's Hospital
Pelvic Organ Prolapse, Gynecologic Cancers
Electronic Catheter Stethoscope
This is an observational, exploratory study designed to collect (record) and analyze normal and abnormal sound data from the human bladder during surgery using a novel sensor-based catheter system (Electronic Catheter…
- Conditions
- Pelvic Organ Prolapse, Gynecologic Cancers, Uterine Leiomyomata, Adenomyosis
- Trial name
- NCT01463462
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of South Florida
Endometriosis, Adenomyosis
Development and Validation of EHP-30 (Hong Kong Chinese Version) for Patients With Endometriosis and Adenomyosis
Endometriosis and adenomyosis can impact on the quality of life including the physical, psychological and social aspects. It is important to include quality of life measurements in evaluating the disease severity and response to…
- Trial name
- NCT03302468
- Where
- Hong Kong
- Volunteers
- 448 people
- Sponsor
- Chinese University of Hong Kong
Indications for Laparoscopic Supracervical Hysterectomy
Use of the Enseal Intrument for Laparoscopic Supracervical Hysterectomy
The use of the EnSeal® instrument for laparoscopic supracervical hysterectomy in a randomized, single-blinded comparison to the conventional procedure.
- Trial name
- NCT01806012
- Testing
- Sealing tissue with the Enseal device, Conventional supracervical hysterectomy
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- University Hospital Tuebingen
Endometriosis, Adenomyosis
Efficacy of Acupuncture on Chronic Pelvic Pain in Women With Endometriosis or Adenomyosis
The purpose of ths study is to determine the efficacy of acupuncture on chronic pelvic pain in women with endometriosis or adenomyosis.
- Conditions
- Endometriosis, Adenomyosis, Pelvic Pain
- Trial name
- NCT01259180
- Testing
- acupuncture treatment
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- East West Neo Medical Center
Adenomyosis
A Prospective Study of Diagnostic Accuracy of Ultrasound
Prospectively-Patients undergoing a hysterectomy for abnormal uterine bleeding (AUB) or pelvic pain will be enrolled in the study, will get pelvic ultrasound at the ultrasound clinic.
- Trial name
- NCT03120078
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Adenomyosis
Accuracy of Endomyometrial Biopsy in Diagnosis of Adenomyosis
This study will compare the accuracy of diagnosing adenomyosis by obtaining hysteroscopic guided endomyometrial biopsy and comparing it to accuracy of diagnosis by transvaginal ultrasound and magnetic resonance imaging.
- Trial name
- NCT05505656
- Testing
- hysteroscopic guided endomyometrial biopsy
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Adenomyosis, Endometriosis
Risk Factors and Disorders Linked to Uterine Adenomyosis on MRI in Reproductive-Age Women
The goal of this observational case-control study is to identify risk factors and associated conditions related to adenomyosis in women of reproductive age.
- Conditions
- Adenomyosis, Endometriosis, Leiomyoma (Uterine Fibroids), Ovarian Cysts
- Trial name
- NCT06697444
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Mashhad University of Medical Sciences
Uterine Fibroids, Menorrhagia
Uterine Artery Embolization for Symptomatic Fibroids
This study will evaluate the safety, efficacy , quality of life and patient satisfaction of uterine artery embolization for the treatment of symptomatic uterine fibroids.
- Conditions
- Uterine Fibroids, Menorrhagia, Adenomyosis
- Trial name
- NCT00354471
- Testing
- Uterine Artery Embolization
- Where
- Canada
- Sponsor
- University of Manitoba
Uterine Adenomyosis, Recurrent Implantation Failure
Aromatase Plus GnRH Analogue Versus GnRH Analog Alone in Adenomyosis
With this study the investigators want to test which is the best medical treatment for symptomatic adenomyosis affecting women undergoing IVF and with previous implantation failure, between Aromatase inhibitor plus GnRH analog…
- Conditions
- Uterine Adenomyosis, Recurrent Implantation Failure, Menstrual Pain
- Trial name
- NCT03421639
- Testing
- GnRH analog (11.25mg Leuprolide acetate), Aromatase inhibitor and GnRH analog, Aromatase and GnRH analog (11.25mg Leuprolide acetate)
- Where
- 3 sites in Albania, Bulgaria and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Uterine Myoma, Uterine Adenomyosis
Study of Different Pain Scores in Single-Port Access (SPA) Laparoscopic Hysterectomy Versus Conventional Laparoscopic Hysterectomy
Purpose: The attempt to further reduce the operative trauma in laparoscopic hysterectomy led in new technique such as Single-Port Access (SPA) laparoscopic surgery.
- Trial name
- NCT01064128
- Testing
- conventional laparoscopic hysterectomy, SPA laparoscopic hysterectomy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Elective Fertility Preservation
Study of the Prevalence of Endometriosis and Adenomyosis
Our study aims to assess the prevalence of adenomyosis and endometriosis in patients consulting for elective fertility preservation through the diagnosis of these pathologies by transvaginal pelvic ultrasound.
- Trial name
- PrevADEOSE (NCT06211569)
- Testing
- Usual follow-up
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Adenomyosis, Pelvic Pain Syndrome
Validation of the Adenomyosis Calculator
Adenomyosis is a disease where ectopic endometrial glands affect the muscular wall of the uterus. Women that suffer from dysmenorrhea or infertility caused by adenomyosis need to confirm or rule out adenomyosis, and therefore…
- Trial name
- NCT04135118
- Where
- 5 sites in Finland, Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Uterine Bleeding, Uterine Fibroids
What Are we Missing? Diagnosing Uterine Adenomyosis Using Ultrasound Elastography
To improve the clinical care of women with pelvic pain and abnormal uterine bleeding due to benign uterine conditions including leiomyomas (uterine fibroids) and adenomyosis by evaluating the accuracy of radiology diagnostic…
- Conditions
- Uterine Bleeding, Uterine Fibroids, Adenomyosis
- Trial name
- NCT01992718
- Testing
- Evaluation of MRI, US for pelvic and uterine conditions, Patient preference between MRI and Ultrasound
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Michigan