Clinical trials: Adherence
Blood Pressure, Vascular Function
Smartphone App-guided Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure
This clinical trial aims to assess the efficacy of inspiratory muscle strength training (IMST) guided by a smartphone app vs. IMST delivered in a clinical research setting for lowering systolic blood pressure in adults 18 years…
- Conditions
- Blood Pressure, Vascular Function, Adherence, Treatment
- Trial name
- NCT06229873
- Testing
- App-Based Inspiratory Muscle Strength Training, Clinic-Based Inspiratory Muscle Strength Training
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Hypertension, Self-Management
Self-Management and Resilience Trajectories in African American Adults With Hypertension
Hypertension (HTN) rates have increased worldwide, but the most significant increase in the incidence of morbidity and mortality has been in African Americans (AA) (43% vs 27% for other U.S. population groups).
- Conditions
- Hypertension, Self-Management, Quality of Life, Compliance, Medication
- Trial name
- NCT05308914
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Case Western Reserve University
Allergy;Food, Adherence, Treatment
The Food Allergy Superheroes Training (FAST) Program
Among children with a food allergy, strict avoidance (e.g., elimination of allergenic foods from one's diet) is the only intervention capable of preventing potentially devastating health-related sequelae including anaphylaxis and…
- Conditions
- Allergy;Food, Adherence, Treatment, Child, Only
- Trial name
- NCT04400214
- Testing
- Food Allergy Superheroes Training (FAST) Program, Food Allergy Knowledge Intervention
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Kent State University
Medication Adherence, Smoking Cessation
Helping People Adhere to Their Varenicline Treatment by Co-creating a Conversational Agent: A Feasibility Study
The goal of this feasibility study is to co-create and evaluate a theory informed, evidence-based, patient-centered healthbot aimed at helping people adhere to their varenicline regimen.
- Trial name
- NCT05997901
- Testing
- Varenicline healthbot
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Peer Influence, Medication Adherence
Effect of Peer Support Intervention on Medication Adherence, Self-care and Knowledge Among Patients With Diabetes
The goal of this interventional study is to learn about the effect of a peer support group intervention on adherence, self-care practice, and knowledge among diabetic patients on follow-up care.
- Conditions
- Peer Influence, Medication Adherence, Self Care
- Trial name
- DM (NCT07145983)
- Testing
- Structured Diabetes Education on medication Adherence and self care
- Where
- Ethiopia
- Volunteers
- 120 people
- Sponsor
- Addis Ababa University
Lung Cancer, Medication Adherence
Implementation Strategies for Monitoring Adherence in Real Time
The objective of this project is to identify effective strategies to help patients with lung cancer manage side effects and achieve optimal adherence to oral targeted therapies.
- Conditions
- Lung Cancer, Medication Adherence, Symptoms and Signs
- Trial name
- iSMART (NCT04347161)
- Testing
- Conversational Agent/Chatbot, Usual Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Heart Failure, Heart Failure Hospitalization
Teach-Back Discharge Education to Improve Self-Care and Reduce 30-Day Readmissions in Heart Failure Patients
This study aimed to improve how patients with heart failure understand and manage their condition after leaving the hospital. Many heart failure patients are readmitted within 30 days due to confusion about their discharge…
- Conditions
- Heart Failure, Heart Failure Hospitalization, Readmission, Hospital
- Trial name
- NCT07280208
- Testing
- Teach-Back Discharge Education
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Nova Southeastern University
Hypertension, Medication Adherence
Mi Propio Camino Intervention RCT for Blood Pressure Medication Adherence
The purpose of this study is to compare the effect of two educational interventions on adherence to blood pressure medications among adults with uncontrolled hypertension.
- Trial name
- MPC (NCT04585594)
- Testing
- Mi Propio Camino (MPC), Habilidades para Controlar la Presion (HCP; Skills for Blood Pressure Control)
- Where
- United States
- Volunteers
- 511 people
- Sponsor
- University of California, Irvine
Breast Cancer, Survivorship
Culturally Aware AET Non-Initiation Intervention
The purpose of this study is to examine the feasibility and acceptability of a brief, nurse-led intervention to support breast cancer survivors who have delayed initiation of hormonal therapy or who have concerns about starting…
- Conditions
- Breast Cancer, Survivorship, Treatment Compliance, Treatment Adherence
- Trial name
- NCT05465408
- Testing
- Culturally Aware Adjuvant Endocrine Therapy (AET) Non-Initiation Intervention
- Where
- 11 sites in United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Heart Failure With Reduced Ejection Fraction, HIV Infections
Heart Failure Polypill at a Safety Net Hospital
A novel four-drug regimen for heart failure with reduced ejection fraction (HFrEF) extends patients' life expectancy by an average of 6 years compared to traditional therapies, in addition to improving quality of life.
- Trial name
- NCT06029712
- Testing
- Heart failure polypill, Control Rx
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Francisco
Opioid-use Disorder, Opioid Dependence
SMART Effectiveness Trial
The current study piloted two psychosocial interventions developed to increase buprenorphine-naloxone adherence in individuals with opioid use disorder (OUD).
- Conditions
- Opioid-use Disorder, Opioid Dependence, Treatment Adherence
- Trial name
- NCT04464421
- Testing
- Contingency Management (CM), Brief Motivational Intervention + Substance Free Activities Session + Mindfulness-Based Adherence Promotion (BSM)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Karen Derefinko, PhD
Cancer, Adherence, Medication
A Pilot Feasibility Trial of a Tailored Intervention to Improve Adherence in Adolescents and Young Adults With Cancer
A pilot feasibility randomized clinical trial comparing a tailored intervention to uniform standard of care will be conducted. A total of 40 AYAs with cancer will be randomized to one of the two programs.
- Trial name
- NCT05706610
- Testing
- Tailored Program, Feedback Program
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asthma in Children, Adherence, Treatment
Treatment Phenotypes for Adolescents With Asthma
This study will evaluate how adolescents take their asthma medications using an electronic medication monitor.
- Trial name
- NCT04228107
- Testing
- Medication monitoring
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Glaucoma
The Support, Educate, Empower (SEE) Program
This study will test whether the Support, Educate, Empower (SEE) personalized Glaucoma Coaching Program improves eye drop medication adherence among glaucoma patients compared to enhanced standard care in a randomized controlled…
- Trial name
- SEE (NCT04735653)
- Testing
- Personalized Glaucoma Coaching, Enhanced Standard care
- Where
- 2 sites in United States
- Volunteers
- 236 people
- Sponsor
- University of Michigan
Study Adherence, Depressive Disorder
Message-Based Psychotherapy and Digital Treatment Sequences for Depression
This partnership between Talkspace and the University of Washington (UW) ALACRITY Center will determine how effective unlimited text-based psychotherapy for depression is when compared to once-a-week psychotherapy.
- Trial name
- NCT04513080
- Testing
- Video-Chat Psychotherapy (VCP), Message-Based Psychotherapy (MBP), Message-Based Psychotherapy with Monthly Video-Chat Psychotherapy
- Where
- United States
- Volunteers
- 1,184 people
- Sponsor
- Talkspace
Adherence, Medication, Risk Reduction
Prevention and Risk: Treatment With a New Emphasis on Relationships
This research examines the efficacy of an individually-delivered intervention tailored for YMSM in relationships. The intervention - termed PARTNER - utilizes a brief (4 session) motivational interviewing format to target…
- Conditions
- Adherence, Medication, Risk Reduction, Drug Use, Sex, Anal
- Trial name
- PARTNER (NCT03396367)
- Testing
- PARTNER, Education Intervention
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Hypertension
Uncontrolled Hypertension Among the Homeless
This study is designed to assess the effect of implementing a mobile health (mHealth) strategy using text messaging for hypertension (HTN) management among hypertensive homeless persons with uncontrolled blood pressure age 21 or…
- Trial name
- NCT05187013
- Testing
- mHealth for Hypertension in Homeless Persons
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- George Washington University
Pulmonary Function, Incentive Spirometry
Digital Incentive Spirometry Adherence
This single-arm proof-of-concept research study aims to assess the effect of a digital incentive spirometer (IS) device and a companion mobile-based app on incentive spirometry adherence in patients post-surgery.
- Conditions
- Pulmonary Function, Incentive Spirometry, Patient Adherence, Lung Resection
- Trial name
- NCT06629454
- Testing
- Adherence to digital incentive spirometer in the postop period after major chest surgery.
- Where
- 6 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Pennsylvania
HIV/AIDS
Brief Acceptance-Based Retention Intervention for Newly Diagnosed HIV Patients
The overall aim of this program of research is to test a newly developed intervention, Acceptance-Based Behavior Therapy (ABBT), to improve HIV patients' commitment to medical care.
- Trial name
- NCT04201288
- Testing
- Acceptance-Based Behavior Therapy (ABBT), Enhanced-Treatment-as-Usual (ETAU)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Brown University
Opioid-use Disorder, Adherence, Medication
Social Networks and Methadone Maintenance Treatment Retention and Antiretroviral Therapy Retention in Tanzania
Investigators will adapt the Brief Social Behaviour and Network Therapy (B-SBNT) intervention developed to facilitate recovery among people receiving medication-assisted treatment for opioid use disorder in the United Kingdom.
- Conditions
- Opioid-use Disorder, Adherence, Medication, HIV Infections
- Trial name
- NCT04479475
- Testing
- Supportive care through community support persons
- Where
- Tanzania
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health