Clinical trials: Adhesion, open to volunteers
Leukocyte Adhesion Deficiency
An Extension Study Assessing the Safety and Efficacy of AVTX-803 in Subjects With Leukocyte Adhesion Deficiency Type II
The primary objective of this extension study is to assess the long-term safety and efficacy of AVTX-803 in subjects with LAD II (SLC35C1-CDG).
- Trial name
- NCT05754450
- Testing
- AVTX-803
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- AUG Therapeutics
Neuroendocrine Neoplasm, Neuroendocrine Carcinomas
Study of CTX-471 in Patients With Neural Cell Adhesion Molecule (NCAM) Positive Neuroendocrine Neoplasms
This study will enroll patients with central lab confirmed NCAM (CD56 IHC) positive metastatic neuroendocrine neoplasms that have progressed after standard of care treatment.
- Conditions
- Neuroendocrine Neoplasm, Neuroendocrine Carcinomas, Neuroendocrine Tumors
- Trial name
- NCT07684170
- Testing
- CTX-471
- Volunteers
- 58 people
- Sponsor
- Compass Therapeutics
Advanced Solid Tumors
A Study of SIGX1094R in Patients With Advanced Solid Tumors
This is a phase I clinical, first-in-human study of SIGX1094R monotherapy. The goal of this trial is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), anti-tumor activity and food effect of…
- Trial name
- NCT06739291
- Testing
- SIGX1094R
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Signet Therapeutics
Leukocyte Adhesion Deficiency
A Study to Evaluate Efficacy and Safety of AVTX-803 in Patients With Leukocyte Adhesion Deficiency Type II
The primary objective of this study is to evaluate the efficacy and safety of AVTX-803 compared to withdrawal in patients with Leukocyte Adhesion Deficiency, Type II (LAD II).
- Trial name
- NCT05462587
- Testing
- AVTX-803 (L-Fucose)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- AUG Therapeutics
Advanced Adenocarcinoma
Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.
The objective of this study is to assess safety and efficacy of BA3182 in Advanced Adenocarcinoma
- Trial name
- NCT05808634
- Testing
- BA3182
- Where
- 9 sites in United States
- Volunteers
- 168 people
- Sponsor
- BioAtla, Inc.
Idiopathic Parkinson Disease
Adhesion and Safety of Rotigexole Compared to Neupro®
A non-inferiority open-labelled crossover randomized controlled trial, of two arms, to investigate the adhesiveness and safety of Rotigexole 8 mg/24 hours transdermal patch, manufactured by Eva pharma, Egypt, compared to the…
- Trial name
- START (NCT07015346)
- Testing
- Rotigexole 8 mg, Neupro ® 8 mg
- Volunteers
- 40 people
- Sponsor
- Eva Pharma
Advanced Solid Tumors
FAK Inhibitor in Patients With Advanced Solid Tumors
This is A Phase I/Ib Study，aimed to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Efficacy of Focal Adhesion Kinase Inhibitor IN10028 as Monotherapy and Combination Therapy in Patients with…
- Trial name
- NCT07596381
- Testing
- IN10028
- Where
- China
- Volunteers
- 75 people
- Sponsor
- InxMed (Shanghai) Co., Ltd.
Surgical Adhesions
JOCOAT Safety and Tolerability Clinical Trial GLAD-04
This study will assess the safety and efficacy of a new liquid anti-adhesion device, JOCOAT(TM) APN-3003 in patients undergoing knee anterior cruciate ligament reconstruction (ACLR) surgery.
- Trial name
- NCT07081815
- Testing
- JOCOAT(TM) APN-3003
- Volunteers
- 24 people
- Sponsor
- ARC Medical Inc.
Intrauterine Abnormalities in Infertility, Asherman Syndrome
Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion
The aim of this study was to obtain short- and long-term performance and safety data of cross-linked hyaluronic acid-based adhesion barrier gel used to prevent intrauterine adhesion formation.
- Conditions
- Intrauterine Abnormalities in Infertility, Asherman Syndrome, Intra-uterine Adhesions, Postoperative Adhesion of Uterus
- Trial name
- SEMFERTIL (NCT07160764)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology