Clinical trials: Adipose-Derived Mesenchymal Stem Cells
Articular Cartilage Lesion of the Femoral Condyle
Autologous Mesenchymal Stem Cells vs. Chondrocytes for the Repair of Chondral Knee Defects
The objective of our study is to compare the safety and effectiveness of the use of autologous cultured adipose tissue-derived stem cells versus cultured autologous chondrocytes for the treatment of chondral knee lesions.
- Trial name
- ASCROD (NCT01399749)
- Testing
- Implantation of autologous cells
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz
Pulmonary Hypertension
Clinical Study of Adipose Derived Mesenchymal Stem Cells for Treatment of Pulmonary Arterial Hypertension
Pulmonary arterial hypertension is a disease characterised by pathological changes in the pulmonary arteries leading to a progressive increase in pulmonary vascular resistance and pulmonary artery pressure.
- Trial name
- NCT04055415
- Testing
- adipose derived mesenchymal stem cells, Conventional drug therapy（expectorant，bronchodilator）
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Liaocheng People's Hospital
Multiple Sclerosis
Multi-Center Study Safety of Adipose Derived Mesenchymal Stem Cells for the Treatment of Multiple Sclerosis
The intent of this clinical study is to answer the questions: 1) is the proposed treatment safe and 2) is treatment effective in improving the disease pathology of patients with Multiple Sclerosis and clinical outcomes.
- Trial name
- NCT02326935
- Testing
- Autologous adipose derived mesenchymal cells
- Where
- Cayman Islands
- Volunteers
- 2 people
- Sponsor
- American CryoStem Corporation
Erectile Dysfunction, Prostate Cancer
Stem Cells for Erectile Dysfunction Post RALP
This is a phase 1/2 single center, pilot study to assess safety and efficacy of allogeneic adipose-derived mesenchymal stem cells (HB-adMSCs) and to evaluate the timing and combination effects of active treatment versus placebo…
- Trial name
- NCT07048314
- Testing
- Allogeneic adipose-derived mesenchymal stem cells (HB-adMSCs) at the doctor's office, Allogeneic adipose-derived mesenchymal stem cells (HB-adMSCs) in the OR
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Methodist Hospital Research Institute
Chronic Endometritis, Uterus; Scar
Fertility Restoration Using Autologous Mesenchymal Stem Cells
Treatment of the patients with scarring and adhesions in the uterus resulting from caesarean section or chronic inflammation in the mucosa of the uterus and fallopian tubes and preventing the occurrence of these effects in the…
- Conditions
- Chronic Endometritis, Uterus; Scar, Uterine Synechiae, Fallopian Tube Obstruction
- Trial name
- NCT04432467
- Testing
- Autologous mesenchymal stem cells, standard treatment
- Where
- Belarus
- Volunteers
- 10 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Liver Transplant; Complications, Liver Diseases
Adipose-Derived Mesenchymal Stem Cell for Preventing Biliary Complications
The purpose of this study is to assess the safety of autologous Adipose-Derived Mesenchymal Stem Cell for use in End-Stage Liver Disease patients undergoing the creation of a duct-to-duct anastomosis during Living Donor Liver…
- Trial name
- NCT06649864
- Testing
- Autologous adipose derived mesenchymal stromal cells (AMSC)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Idiopathic Parkinson's Disease
Evaluating Safety, Tolerability, and Efficacy of Autologous MitoCell Transplantation in Subjects With Idiopathic Parkinson's Disease
Primary Objective: To assess the safety profile of autologous MitoCell administered to subjects with idiopathic Parkinson's disease (PD) Secondary Objective: To explore the efficacy and safety of MitoCell given as the recommended…
- Trial name
- NCT05094011
- Testing
- Aadipose-Derived Mesenchymal Stem Cells
- Volunteers
- 9 people
- Sponsor
- Taiwan Mitochondrion Applied Technology Co., Ltd.
Osteoarthritis
ADIPOA - Clinical Study
Primary: To study the safety of a single injection of autologous adipose derived mesenchymal stromal cells (ASCs) on patients with moderate or severe osteoarthritis of the knee (OA).
- Trial name
- NCT01585857
- Testing
- Autologous adipose derived stem cells administrated for intra-articular use
- Where
- 2 sites in France, Germany
- Volunteers
- 18 people
- Sponsor
- University Hospital, Montpellier
ARDS
Adipose-derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome
Currently, there is no proven effective pharmacologic treatment available for patients with the acute respiratory distress syndrome (ARDS).
- Trial name
- NCT01902082
- Testing
- Mesenchymal stem cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shaoxing Second Hospital
Alzheimer Disease
the Safety and the Efficacy Evaluation of Allogenic Adipose MSC-Exos in Patients With Alzheimer's Disease
Evaluate the Safety and Efficacy of Exosomes Derived from Allogenic Adipose Mesenchymal Stem Cells（MSCs-Exos）in Subjects with Alzheimer's disease.
- Trial name
- NCT04388982
- Testing
- low dosage MSCs-Exos administrated for nasal drip, mild dosage MSCs-Exos administrated for nasal drip, high dosage MSCs-Exos administrated for nasal drip
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Ruijin Hospital
Osteoarthritis
Clinical Trial of Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells Therapy for Knee Osteoarthritis
Evaluate the safety and efficacy of Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells Therapy for Knee Osteoarthritis.
- Trial name
- NCT02641860
- Testing
- Mesenchymal progenitor cells
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Shanghai AbelZeta Ltd.
Rotator Cuff Disease
Autologous Adipose Tissue Derived Mesenchymal Stem Cells for Rotator Cuff Disease
The purpose of this study is to evaluate safety and efficacy of Autologous Adipose Tissue Derived Mesenchymal Stem Cells injection in patient with Rotator Cuff disease.
- Trial name
- NCT02474342
- Testing
- Autologous Adipose Tissue Derived MSCs Transplantation
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Seoul National University Hospital
Focal Segmental Glomerulosclerosis
Allogenic AD-MSC Transplantation in Idiopathic Nephrotic Syndrome (Focal Segmental Glomerulosclerosis)
Idiopathic Focal Segmental Glumero Sclerosis (FSGS) is not very common but important manifestation of kidney disease. FSGS has poor prognosis among the patterns of Idiopathic Nephrotic Syndrome (INS).
- Trial name
- NCT02382874
- Testing
- Intravenous injection
- Where
- Iran
- Volunteers
- 5 people
- Sponsor
- Royan Institute
Liver Cirrhosis
Mesenchymal Stem Cells Transplantation for Liver Cirrhosis Due to HCV Hepatitis
In this study, investigators aimed to transplant autologous, adipose tissue derived mesenchymal stem cells to the patients with liver cirrhosis due to HCV.
- Trial name
- NCT02705742
- Testing
- Mesenchymal Stem Cells
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Urinary Incontinence
Stem Cells Tratment for the Local Feminine Stress Urinary Incontinence Treatment (HULPURO)
Evaluate the feasability and security of the autologous ASC for the femenine stress urinary incontinence
- Trial name
- HULPURO (NCT01804153)
- Testing
- Adipose-derived expanded stem cells
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Aging Well, Regenerative Medicine
MSC Infusion for Anti-aging and Regenerative Therapy
To evaluate the safety and efficacy of human Mesenchymal Stem Cell (hMSC) infusion therapy, in preserving general wellness and ameliorating or reversing the effects of aging in our study population
- Trial name
- REGEN (NCT04174898)
- Testing
- human Mesenchymal Stem Cell (MSC) infusion therapy
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Landmark Medical Centre Sdn Bhd
COVID-19
Autologous Adipose-derived Stem Cells (AdMSCs) for COVID-19
This is a phase 2 multi-center, double-blind, randomized, placebo-control clinical trial with 200 subjects who have never been infected by COVID-19 (SARS-Cov-2 virus screen test negative, no blood SARS-Cov-2 IgM and IgG…
- Trial name
- NCT04428801
- Testing
- autologous adipose-derived stem cells
- Volunteers
- 200 people
- Sponsor
- Celltex Therapeutics Corporation
Pancreatic Cancer
Individual Patient Expanded Access IND of Hope Biosciences First Blood Relative Allogeneic Adipose-derived Mesenchymal Stem Cells (HB-adMSCs) for Pancreatic Cancer
The drug for this submission is Hope Biosciences' allogeneic, first blood relative, adipose-derived culture-expanded mesenchymal stem cells (HB-adMSCs) for the treatment of a single patient with Pancreatic Cancer (PC).
- Trial name
- NCT04087889
- Testing
- HB-adMSCs
- Where
- United States
- Sponsor
- Hope Biosciences LLC
Urinary Incontinence Stress
Allogeneic Use of Expanded Mesenchymal Stem Cells Derived From Adipose Tissue (HC106), Female Urinary Incontinence Women Over 50 Years Old
Evaluate the feasibility and safety, obtaining initial efficacy data, of expanded allogeneic mesenchymal stem cells derived from adipose tissue (HC106) for the treatment of urinary incontinence in women over 50 years of age.
- Trial name
- SUITH) (NCT06738576)
- Testing
- allogeneic mesenchymal stem cells
- Where
- 6 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Atrophic Scar
Safety and Tolerability of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and tolerability for 12 weeks after one dose of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT06210919
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- CellinCells