Clinical trials: Adipose-Derived Mesenchymal Stem Cells
COVID-19
Efficacy and Safety Study of Allogeneic HB-adMSCs for the Treatment of COVID-19
Hope Biosciences is conducting a research study of an investigational product called allogeneic adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) as treatment for patients suspected to have COVID-19.
- Trial name
- NCT04362189
- Testing
- HB-adMSC
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Hope Biosciences Research Foundation
Osteoarthritis, Knee
A Phase 2 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis
This study is a double-blind, randomized, controlled study with two arms to evaluate JointStem as a treatment for subjects with osteoarthritis.
- Trial name
- NCT02674399
- Testing
- JointStem, Synvisc-One
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Nature Cell Co. Ltd.
COVID-19
A Randomized, Double-Blind, Single Center, Efficacy and Safety Study of Allogeneic HB-adMSCs Against COVID-19.
Hope Biosciences is conducting a research study of an investigational product called allogeneic adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) to provide immune support against COVID-19.
- Trial name
- NCT04348435
- Testing
- HB-adMSCs
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hope Biosciences Research Foundation
Rotator Cuff Tear
Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells (Rotator Cuff Tear)
Main purpose of this study is to evaluate efficacy of allogenic adipose-derived mesenchymal stem cells in treatment of tendon injury.
- Trial name
- NCT02298023
- Testing
- allogenic adipose stem cell injection, fibrin glue/normal saline injection, normal saline injection
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Lateral Epicondylitis
Treatment of Tendon Injury Using Mesenchymal Stem Cells
Main purpose of this study is to evaluate efficacy and safety of allogenic adipose-derived mesenchymal stem cells(ALLO-ASC) in treatment of tendon injury.
- Trial name
- ALLO-ASC (NCT01856140)
- Testing
- ALLO-ASC(allogeneic adipose derived mesenchymal stem cell) injection
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Hospital
Osteoarthritis
Multicenter Trial of Stem Cell Therapy for Osteoarthritis (MILES)
The study is a multicenter trial conducted to compare the effectiveness of an injection of a corticosteroid control to mesenchymal stem cell (MSC) preparations from autologous bone marrow concentrate (BMAC), adipose derived stem…
- Trial name
- MILES (NCT03818737)
- Testing
- Bone Marrow Derived MSCs, Adipose-derived MSCs, Umbilical Cord Tissue (UCT) MSCs
- Where
- 5 sites in United States
- Volunteers
- 475 people
- Sponsor
- Emory University
ALS, Amyotrophic Lateral Sclerosis
Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)
The purpose of this study is to determine the safety and efficacy of intrathecal treatment delivered to the cerebrospinal fluid (CSF) of mesenchymal stem cells in ALS patients every 3 months for a total of 4 injections over 12…
- Trial name
- NCT03268603
- Testing
- Autologous Adipose-derived Mesenchymal Stromal Cells
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- Mayo Clinic
Systemic Sclerosis
Injection of Autologous Adipose-derived Stromal Vascular Fraction in the Finger of Systemic Sclerosis Patients
This study outlines the safety of the autologous SVF cells injection in the hands of patients with SSc. Preliminary assessments at 6 months will suggest potential efficacy needing confirmation in a randomised placebo-controlled…
- Trial name
- NCT03060551
- Testing
- SVF injection
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Suk-Ho Moon
Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma
MV-NIS Infected Mesenchymal Stem Cells in Treating Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer
This phase I/II trial studies the side effects and best dose of oncolytic measles virus encoding thyroidal sodium iodide symporter (MV-NIS) infected mesenchymal stem cells and to see how well it works in treating patients with…
- Conditions
- Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Mucinous Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma
- Trial name
- NCT02068794
- Testing
- Laboratory Biomarker Analysis, Mesenchymal Stem Cell Transplantation, Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Mayo Clinic
Breast Reconstruction, Contour Irregularities
Immunophenotyping of Fresh Stromal Vascular Fraction From Adipose Derived Stem Cells (ADSC) Enriched Fat Grafts
The purpose of this study is to investigate if there is a relationship between the take of fat grafts with and without ADSCs and the presence of specific surface markers on the cells of the stromal vascular fraction.
- Conditions
- Breast Reconstruction, Contour Irregularities, Volume Insufficiency
- Trial name
- NCT01771913
- Testing
- centrifuged fat graft, ADSCs enriched fat graft
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Alzheimer Disease
A Study to Evaluate the Safety and Efficacy of AstroStem in Treatment of Alzheimer's Disease
This is a randomized, double-blind, placebo-controlled, parallel-group comparison study in subjects with Alzheimer's Disease. Following first screening period, subjects will be randomly assigned into one of the following arms…
- Trial name
- NCT03117738
- Testing
- AstroStem
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Nature Cell Co. Ltd.
COVID-19
A Clinical Trial to Determine the Safety and Efficacy of HB-adMSCs to Provide Protection Against COVID-19
Hope Biosciences is conducting a research study of an investigational product called autologous adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) to provide immune support against COVID-19.
- Trial name
- NCT04349631
- Testing
- HB-adMSCs
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hope Biosciences Research Foundation
Rheumatoid Arthritis
Phase 1/2a Clinical Trial to Assess the Safety of HB-adMSCs for the Treatment of Rheumatoid Arthritis
Hope Biosciences is conducting a research study of an investigational product called Hope Biosciences autologous adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) as a possible treatment for Rheumatoid Arthritis…
- Trial name
- HB-adMSCs (NCT03691909)
- Testing
- HB-adMSCs
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Hope Biosciences LLC