Clinical trials: Adjuvant Treatment
Transitional Cell Carcinoma of Bladder, Superficial Bladder Cancer
Mitomycin C With Hyperthermia and Intravesical Mitomycin C to Treat Recurrent Bladder Cancer
Hypothesis: In selected patients external hyperthermia will be used in combination with intravesical Mitomycin-C (MMC) to treat recurrent transitional cell carcinoma (TCC) of the bladder after local resection and standard…
- Trial name
- NCT00734994
- Testing
- Hyperthermia System, Mitomycin C
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mark Dewhirst
Breast Cancer
Safety and Efficacy of ALC in Breast Cancer in Subjects With Fatigue
The objective of this study is to evaluate the efficacy and safety of ALC in the treatment of non-anemic, breast cancer subjects who develop moderate or severe fatigue during adjuvant radiotherapy.
- Trial name
- NCT00555841
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Sigma-Tau Research, Inc.
Endometrial Cancer, Papillary Serous
Vaginal Cuff Brachytherapy Followed by Chemotherapy in Endometrial Cancer
The purpose of this study is to determine the feasibility of treatment in patients with high risk endometrial cancer treated by vaginal cuff brachytherapy followed by 3 cycles of dose dense paclitaxel and carboplatin chemotherapy.
- Conditions
- Endometrial Cancer, Papillary Serous, Clear Cell Endometrial Cancer
- Trial name
- NCT03189446
- Testing
- Vaginal Cuff Brachytherapy, Carboplatin, Paclitaxel
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Oklahoma
Breast Cancer, Osteoporosis
Traditional Chinese Medicine as Preventive Method for Osteoporosis Induced by Adjuvant Endocrine Therapy
To test the efficacy of two Traditional Chinese Medicine in preventing osteoporosis in patients receiving adjuvant endocrine therapy.
- Trial name
- COAT (NCT02455154)
- Testing
- Letrozole, Zhongyaofufang, Xianlinggubao
- Where
- China
- Volunteers
- 278 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Hepatocellular Carcinoma
Neoadjuvant and Adjuvant Lenvatinib in HCC Patients Treated by Percutaneous Ablative
Percutaneous ablation (PA) is the only non-surgical curative treatment of hepatocellular carcinoma (HCC). Due to its excellent tolerance, particularly in patients with portal hypertension or bearing comorbidities, it now…
- Trial name
- LENVABLA (NCT05113186)
- Testing
- Lenvatinib Pill
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Grade 3/4 Neutropenia, Febrile Neutropenia
Study of Danggui Buxue Decoction in Preventing Neutropenia
To evaluate EC/TC (epirubicin and cyclophosphomide or docetaxel and cyclophosphomide) with EC/TC plus DBD (Danggui Buxue Decoction) in adjuvant treatment of breast cancer patients.
- Trial name
- DIPE (NCT02005783)
- Testing
- DBD, Epirubicin, Cyclophosphamide
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Breast Cancer, Letrozole
Safety and Efficacy Study of Femara(Letrozole) as an Extended Adjuvant Treatment in Breast Cancer Patients
Title of study: An observational, multicenter study on the safety and efficacy of Femara® (Letrozole) as an extended adjuvant treatment in breast cancer patients who completed adjuvant Tamoxifen or Toremifen treatment Objectives…
- Trial name
- NCT01249456
- Where
- South Korea
- Volunteers
- 392 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer
Study of Dose-dense Adriamycin Plus Cytoxan (AC) Followed by Either ABI-007 (Abraxane) or Taxol With Bevacizumab as Adjuvant Therapy for Patients With Breast Cancer
The primary objective of this study was to compare the safety of dose-dense ABI-007 (Abraxane) 260 mg/m^2 or Taxol 175 mg/m^2 given every 2 weeks following dose-dense Adriamycin plus Cytoxan (AC) chemotherapy.
- Trial name
- NCT00394251
- Testing
- Adriamycin and Cytoxan (AC), ABI-007, Taxol
- Where
- 27 sites in United States
- Volunteers
- 197 people
- Sponsor
- Celgene
Breast Cancer, Gastric Cancer
Vaccine Therapy in Treating Patients With Metastatic or Recurrent Cancer
RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. PURPOSE: Phase I trial to study the effectiveness of vaccine therapy in treating patients who have metastatic or recurrent cancer.
- Conditions
- Breast Cancer, Gastric Cancer, Lung Cancer, Ovarian Cancer
- Trial name
- NCT00017537
- Testing
- MVF-HER-2(628-647)-CRL 1005 vaccine
- Sponsor
- University of Alabama at Birmingham
HCC
Triple vs. Dual Adjuvant Therapy Following Liver Resection for HCC.
Vessels that encapsulate tumor clusters (VETC) is an invasive metastatic factor in HCC independent of the epithelial mesenchyme transition (EMT), and VETC-positive patients have a higher rate of postoperative recurrence.
- Trial name
- NCT06311942
- Testing
- HAIC plus PD-1 inhibitors plus lenvatinib, PD-1 inhibitors plus lenvatinib
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chen Xiaoping
Breast Neoplasms
Antiestrogen vs Aromatase Inhibitor After Adjuvant Chemotherapy for Breast Cancer
To investigate the benefit of postoperative adjuvant therapy using sequential administration of the hormone, toremifene citrate (TOR) or anastrozole (ANA), after chemotherapy in breast cancer.
- Trial name
- NCT00437359
- Testing
- Toremifene citrate, Anastrozole
- Where
- 7 sites in Japan
- Volunteers
- 240 people
- Sponsor
- Japan Breast Cancer Research Network
Conduct Disorder
The Efficacy and Safety of Oral Oxcarbazepine 300-1200 mg/Day as Adjuvant Therapy in the Treatment of Adolescents With Impulsivity and Aggressive Behavior in Conduct Disorder This Study is Not Being Conducted in the United States.
Conduct disorder is a group of psychiatric symptoms that can include clinical characteristics of impulsivity and aggressive behavior.
- Trial name
- NCT00154362
- Testing
- Oxcarbazepine
- Volunteers
- 50 people
- Sponsor
- Novartis
Hepatocellular Carcinoma
Adjuvant PD-1 Inhibitor for Patients With Early-stage Hepatocellular Carcinoma Following Microwave Ablation
For early-stage hepatocellular carcinoma, i.e. Barcelona Clinical Liver Cancer Stage 0, ablation is the standard treatment with a comparable prognosis and less risk of ablation compared with liver resection.
- Trial name
- NCT06248554
- Testing
- PD-1 Inhibitors
- Where
- China
- Volunteers
- 251 people
- Sponsor
- Chen Xiaoping
Curable Hepatitis B Virus-Related Hepatocellular Carcinoma
Thymalfasin Adjuvant Therapy in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC) After Curative Resection
Efficacy and safety of Thymalfasin adjuvant therapy in HBV-related HCC after curative resection.
- Trial name
- NCT02281266
- Testing
- curative resection, thymalfasin, nucleoside analog (suggest to use entecavir)
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Jia Fan
Cholangiocarcinoma
Study on Consistency Evaluation for Drug Sensitivity of Patient-Derived Organoid Model From Cholangiocarcinoma Patients
This is a single-center, prospective, observational and exploratory clinical study. The object of this study is to evaluate the consistency and accuracy of patient-derived organoid model of cholangiocarcinoma to predict the…
- Trial name
- NCT05634694
- Testing
- No interventions.
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer
COMPORT is a multicenter phase II clinical trial evaluating a personalized approach to postoperative radiotherapy in patients with head and neck squamous cell carcinoma (HNSCC).
- Conditions
- Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma
- Trial name
- COMPORT (NCT07058805)
- Testing
- Compartmentalized Postoperative Radiotherapy
- Where
- 3 sites in Switzerland
- Volunteers
- 50 people
- Sponsor
- Olgun Elicin
H1N1 Influenza
Collaborative H1N1 Adjuvant Treatment (CHAT) Pilot Trial
The CHAT Pilot Trial is designed to compare rosuvastatin against placebo in patients with suspected H1N1. The pilot study will assess the feasibility of our clinical protocols, and study procedures.
- Trial name
- CHAT Pilot (NCT01798602)
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Canadian Critical Care Trials Group
Breast Neoplasms
Prayer as a Possible Adjuvant Treatment for Breast Cancer
The goal of this study is to help determine the biochemical mechanisms underlying previously demonstrated health benefits of prayer, and to track humoral changes in various prayer activities.
- Trial name
- NCT00519545
- Testing
- Prayer
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Southwestern Regional Medical Center
Female Breast Cancer
Dose Dense TC + Pegfilgrastim Support for Breast Cancer
The purpose of this study is to determine the feasibility of giving standard TC chemotherapy on a dose dense schedule (ddTC) as well as evaluating the nature and frequency of ddTC side effects.
- Trial name
- ddTC (NCT01671319)
- Testing
- docetaxel + cyclophosphamide + pegfilgrastim
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Wisconsin, Madison
Severe Obesity
Mazdutide as Adjuvant Therapy Following Sleeve Gastrectomy in Severe Obesity
The SMART study is a 96-week, multicenter, randomized, double-blind, placebo-controlled superiority clinical trial. A total of 256 severe obesity patients are randomized 1:1 to either receive the bariatric surgery plus GCG/GLP-1…
- Trial name
- SMART (NCT07135141)
- Testing
- Sleeve gastrectomy plus early mazdutide initiation
- Where
- 14 sites in China
- Volunteers
- 256 people
- Sponsor
- Beijing Friendship Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.