Clinical trials: Adnexal Mass
Ovarian Tumor
EURAD MRI Classification of US Indeterminate Adnexa Lesions
This research is targeting patients with sonographically indeterminate adnexal mass that are being referred for clinical MR imaging.
- Trial name
- NCT02962596
- Testing
- ADNEXMR SCORING system
- Where
- United States
- Volunteers
- 1,340 people
- Sponsor
- University of Wisconsin, Madison
Ovarian Cancer, Ovarian Tumor
AI Analysis of CT Scans to Classify Ovarian Tumours as Benign, Borderline or Malignant Before Surgery
The goal of this observational study is to learn if a computer program can tell what type of ovarian tumour a person has from a CT scan taken before surgery. The program uses artificial intelligence (AI).
- Conditions
- Ovarian Cancer, Ovarian Tumor, Borderline Ovarian Tumor
- Trial name
- OvaClass (NCT07883551)
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 1,300 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Gynecology
IOTA Versus Pattern Recognition Method in Diagnosis of Ovarian Masses
To compare between the efficacy of IOTA simple rules and pattern recognition method in the differentiating between benign and malignant adnexal masses
- Trial name
- NCT02800031
- Testing
- Transvaginal ultrasonography
- Where
- Egypt
- Volunteers
- 396 people
- Sponsor
- Woman's Health University Hospital, Egypt
Ovarian Mass, Adnexal Mass
An AI-Assisted Agentic System for Ultrasound Scanning and Diagnosis of Ovarian Lesions
Investigators developed an interactive agentic system designed to guide newly qualified sonographers in ovarian lesion scanning and improve their scanning quality and diagnostic performance toward expert-level standards.
- Trial name
- NCT07801209
- Testing
- non-AI assisted and then AI assisted, AI assisted and then non-AI assisted
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Adnexal Masses, Ovarian Cysts
International Ovarian Tumour Analysis (IOTA) Phase 5
The purpose of this study is to learn more about the appearance and behavior of benign-looking adnexal masses. Benign-looking means that when viewed here by ultrasound it has the appearance of looking not harmful or not…
- Conditions
- Adnexal Masses, Ovarian Cysts, Ovarian Tumors
- Trial name
- IOTA-5 (NCT01698632)
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- KU Leuven
Ovarian Tumor
EURAD-MR Classification : European Multicenter Study
An adnexal mass is the most common indication for gynaecological surgery . Pre operative characterization is crucial and a scoring system would be useful to standardize the imaging report and thus, improve patient management.
- Trial name
- EURAD (NCT01738789)
- Where
- 24 sites in Austria, Croatia and 6 more
- Volunteers
- 1,340 people
- Sponsor
- Société d'Imagerie de la Femme
Adnexal Mass, Ovarian Cancer
Clinical Validation of the InterVenn Ovarian CAncer Liquid Biopsy
Venn Biosciences Corporation ("InterVenn") has developed a liquid biopsy that is capable of distinguishing benign from malignant masses in women presenting with adnexal (pelvic) masses, through a simple blood test.
- Conditions
- Adnexal Mass, Ovarian Cancer, Pelvic Mass
- Trial name
- VOCAL (NCT03837327)
- Where
- 26 sites in United States, Australia and 2 more
- Volunteers
- 1,025 people
- Sponsor
- Venn Biosciences Corporation
Ovarian Cancer
Contrast-Enhanced Ultrasonography in Diagnosing Early-Stage Ovarian Cancer in Patients With an Adnexal Mass Undergoing Surgery to Remove the Ovary
RATIONALE: New diagnostic procedures, such as contrast-enhanced ultrasonography, may be an effective method of finding ovarian cancer.
- Trial name
- NCT00626873
- Testing
- Definity, medical chart review
- Where
- 3 sites in United States
- Volunteers
- 67 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Adnexal Mass, Germline BRCA1 Gene Mutation
Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection
The objective of this project is to validate a next-generation assay that utilizes both the protein biomarkers of our already established ovarian cancer risk assessment combined with a molecular profile in both germline and early…
- Conditions
- Adnexal Mass, Germline BRCA1 Gene Mutation, Germline BRCA2 Gene Mutation, Hereditary Breast and Ovarian Cancer
- Trial name
- OVA360 (NCT04668521)
- Testing
- OVA360
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Aspira Women's Health
Cancer Debulking, Enlarged Uterus
Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy
To determine if opioid consumption postoperatively among patients undergoing non-emergent laparotomy by the gynecologic oncology service who receive intrathecal morphine with intraoperative lidocaine (IML) infusion are lower than…
- Conditions
- Cancer Debulking, Enlarged Uterus, Fibroid Uterus, Adnexal Mass
- Trial name
- NCT05017246
- Testing
- Bupivacaine, Morphine, Lidocaine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Washington University School of Medicine
Polycystic Ovary Syndrome
Serum Preptin and Amylin Levels in Polycystic Ovary Syndrome Patients
Preptin and amylin are pancreatic hormones which participate in glucose homeostasis. This study aims to evaluate how serum preptin and amylin levels are altered in polycystic ovary syndrome (PCOS) patients and healthy women based…
- Trial name
- NCT03587415
- Testing
- preptin and amylin level
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Adnexal Mass, Borderline Ovarian Epithelial Tumor
Folate Receptor in Diagnosing Ovarian Cancer Using Serum Samples From Patients With Newly Diagnosed Pelvic Mass or Previously Diagnosed Ovarian Cancer
This pilot research trial studies folate receptor in diagnosing ovarian cancer using serum samples from patients with a newly diagnosed pelvic mass or previously diagnosed ovarian cancer.
- Conditions
- Adnexal Mass, Borderline Ovarian Epithelial Tumor, Ovarian Clear Cell Tumor, Ovarian Endometrioid Tumor
- Trial name
- NCT02520115
- Testing
- Dexamethasone, Laboratory Biomarker Analysis, Valproic Acid
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Endometrial Disorder
Correlation Between Adnexal Masses and Endometrial Thickness Measured With Ultrasound in Adults Women
This study explores the correlation between adnexal masses and endometrial thickness in adult women, using ultrasound as the primary diagnostic tool.
- Trial name
- NCT06763393
- Testing
- Ultrasound
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Superior University
Demographic Findings, Presenting Symptoms on First Hospital Visit
Clinical Characteristics of Patients Under the Age 21 Years Who Underwent Gynecological Surgery
Young patients with adnexal lesions may have variable presenting symptoms. In this study, we reviewed the clinical characteristics of young Korean patients who took the operation in university hospital with adnexal lesions over…
- Conditions
- Demographic Findings, Presenting Symptoms on First Hospital Visit, Preoperative Radiologic Findings, Operation Method
- Trial name
- NCT00928369
- Volunteers
- 494 people
- Sponsor
- Samsung Medical Center
Epithelial Ovarian Cancer, Adnexal Mass
Diagnosis of Epithelial Ovarian Cancer Using Ovarian Cancer Score (OCS) Test
The study is designed to confirm the performance of the 3D Medicines Corporation OCS test in diagnosis of epithelial ovarian cancer in patients with adnexal mass.
- Trial name
- NCT06366997
- Where
- China
- Volunteers
- 1,352 people, healthy volunteers welcome
- Sponsor
- Chongqing University Cancer Hospital
Ovarian Cancer
Diagnostic Utility of Culdocentesis in Patients With a Suspicious Adnexal Mass
This study involves women who are scheduled to have surgery for a pelvic or ovarian mass that is suspicious for epithelial ovarian cancer (EOC).
- Trial name
- NCT02109367
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Southern Illinois University
Fallopian Tube Serous Adenocarcinoma, High Grade Ovarian Serous Adenocarcinoma
Talazoparib in Determining Genetic Effects on Disease Response in Patients With Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
This pilot early phase I trial studies talazoparib to determine if certain characteristics of the deoxyribonucleic acid (DNA) affect how the disease responds to therapy in patients with ovarian, fallopian tube, or primary…
- Conditions
- Fallopian Tube Serous Adenocarcinoma, High Grade Ovarian Serous Adenocarcinoma, Ovarian Mass, Primary Peritoneal Serous Adenocarcinoma
- Trial name
- POSITION (NCT02316834)
- Testing
- Laboratory Biomarker Analysis, BMN 673
- Where
- 6 sites in United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Adnexal Mass, Ovarian Cancer
Ovarian Cancer Risk Estimation in Patients With Pelvic Mass
The purpose of this study is to determine whether the Risk of Ovarian Cancer Algorithm (ROMA) is effective in the determination of a woman's risk of cancer when she is scheduled to have surgery to remove a pelvic mass.
- Trial name
- NCT00987649
- Where
- 13 sites in United States
- Volunteers
- 512 people
- Sponsor
- Fujirebio Diagnostics, Inc.
Adnexal Mass, Adnexal Tumor
Masses in Young Patients - International Ovarian Tumour Analysis (MY-IOTA)
This multicenter observational study aims to validate the IOTA Simple Rules, Benign Descriptors, and ADNEX model in a cohort of patients equal or under the age of 20.
- Conditions
- Adnexal Mass, Adnexal Tumor, Adnexal Cyst, Adnexal Masses in Young Girls and Adolescents
- Trial name
- MY-IOTA (NCT06693596)
- Testing
- Group 2: Conservative management (follow-up), Group 1: Surgical management
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ectopic Pregnancies
Adnexal Mass After Methotrexate Treatment for Ectopic Pregnancies
Ectopic pregnancies are a common morbidity in the gynaecological field. Previous work done by our team has shown the benefits of conservative treatment with only BHCG (Beta-Human Chorionic Gonadotropin) monitoring, proving that a…
- Trial name
- NCT03138694
- Testing
- BHCG monitoring
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center