Clinical trials: Adnexal Masses
Patients With a Sonographically Unclassifiable Adnexal Mass Using the IOTA Simple Rules
Value of MRI in the Characterization of Ovarian Masses Unable to Classify With Ultrasound Using the International Ovarian Tumor Analysis (IOTA) Simple Rules
Gynecological ultrasound is well known as the preferred exam to assess patients with ovarian tumors. The International Ovarian Tumor Analysis (IOTA) group developed the 'Simple Rules' to classify an ovarian tumor as benign or…
- Trial name
- IOTA-MRI (NCT02836275)
- Testing
- Diffusion/Perfusion-weighted Magnetic Resonance Imaging
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- KU Leuven
Adnexal Mass
A Multivariate Index Assay for Ovarian Cancer Risk Assessment in Women With Adnexal Mass and High-Risk Germline Variants
The objective of this project is to validate the sensitivity, specificity, positive predictive value and negative predictive values of the AMRA blood test for assessing risk of cancer in women at high risk for ovarian cancer, due…
- Trial name
- OVAnex (NCT04487405)
- Testing
- OVAnex
- Where
- 9 sites in United States
- Volunteers
- 721 people
- Sponsor
- Aspira Women's Health
Epithelial Ovarian Cancer, Adnexal Mass
Diagnosis of Epithelial Ovarian Cancer Using Ovarian Cancer Score (OCS) Test
The study is designed to confirm the performance of the 3D Medicines Corporation OCS test in diagnosis of epithelial ovarian cancer in patients with adnexal mass.
- Trial name
- NCT06366997
- Where
- China
- Volunteers
- 1,352 people, healthy volunteers welcome
- Sponsor
- Chongqing University Cancer Hospital
Ovarian Cancer, Ovarian Tumor
AI Analysis of CT Scans to Classify Ovarian Tumours as Benign, Borderline or Malignant Before Surgery
The goal of this observational study is to learn if a computer program can tell what type of ovarian tumour a person has from a CT scan taken before surgery. The program uses artificial intelligence (AI).
- Conditions
- Ovarian Cancer, Ovarian Tumor, Borderline Ovarian Tumor
- Trial name
- OvaClass (NCT07883551)
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 1,300 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Ovarian Neoplasms, Ovarian Cancer
Improved Diagnosis of Ovarian Cancer
After implementation of systematic image description of adnexal masses, we aim to improve and evaluate our use of available imaging methods and biomarkers for classifying adnexal masses and distinguishing between benign and…
- Conditions
- Ovarian Neoplasms, Ovarian Cancer, Ovarian Cysts, Adnexal Mass
- Trial name
- NCT05842629
- Where
- Denmark
- Volunteers
- 1,700 people
- Sponsor
- University of Aarhus
Adnexal Mass
The Use of International Ovarian Tumor Analysis and Assessment of Adnexal Neoplasia in Differentiating Malignant and Benign Adnexal Masses
All participants will be subjected to Serum measurements of CA-125 by the immunoradiometric assay, Ultrasound evaluation of the Adnexal masses which is described according to origin (ovarian/extraovarian); position…
- Trial name
- NCT03442881
- Testing
- Excision of adnexal mass through laprotomy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Ovarian Tumor
EURAD-MR Classification : European Multicenter Study
An adnexal mass is the most common indication for gynaecological surgery . Pre operative characterization is crucial and a scoring system would be useful to standardize the imaging report and thus, improve patient management.
- Trial name
- EURAD (NCT01738789)
- Where
- 24 sites in Austria, Croatia and 6 more
- Volunteers
- 1,340 people
- Sponsor
- Société d'Imagerie de la Femme
Endometriosis, Fibroids
Impact of Educational Videos on Pre-operative Anxiety
The goal of this clinical trial is to learn if educational videos can reduce pre-operative anxiety in patients undergoing minimally invasive gynecologic surgery.
- Conditions
- Endometriosis, Fibroids, Adenomyosis, Pelvic Pain
- Trial name
- NCT07740759
- Testing
- educational video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UConn Health
Complex Adnexal Masses
MRI Perfusion in Adnexal Masses
As ovarian cancer is characterized by an anarchic neovascularization resulting in a wide number of immature microvessels. These vessels are characterized by a lack of coverage by pericytes and the higher expression of one of the…
- Trial name
- MRI-CAM (NCT02694406)
- Testing
- MRI perfusion
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Sonography, Ovarian Mass
Sonographic Evaluation of Ovarian Masses by ORADS System
This observational study will evaluate how well an ultrasound scoring system called O-RADS can distinguish between benign (non-cancerous) and malignant (cancerous) ovarian masses in women aged 18 to 70 years.
- Trial name
- NCT07289126
- Volunteers
- 80 people
- Sponsor
- Assiut University
Ovarian Cancer, Ovarian Mass
MIRRORS-FROZEN - Comparing Open Vs Robotic Surgery in the Management of Women with Complex Pelvic Adnexal Masses ≤ 8cm.
Adnexal masses are growths that can form in the ovaries or fallopian tubes for different reasons, such as hormonal changes, infection, or cancer.
- Conditions
- Ovarian Cancer, Ovarian Mass, Ovarian Cysts, Fallopian Tube Neoplasms
- Trial name
- MIRRORS-FROZEN (NCT06638593)
- Testing
- MIRRORS-FROZEN Protocol., Standard open surgery
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Patients With Adnexal Mass Prior to Surgery
Prospective Validation and Comparison of Different Ultrasound Methods for Discrimination Between Benign and Malignant Ovarian/Tubal Masses Prior to Surgery
The ability of different methods to discriminate between benign and malignant adnexal masses has been compared in a meta-analysis showing that the IOTA Simple Rules and the IOTA logistic regression model LR2 were superior to RMI…
- Trial name
- IOTA7 (NCT02847832)
- Testing
- Standardized transvaginal ultrasound examination
- Where
- Belgium
- Volunteers
- 1,700 people
- Sponsor
- KU Leuven
Ovarian Cancer, Fallopian Tube Cancer
Nudge to Gynecologic Oncology
Ovarian cancer lacks an effective screening test, and prompt treatment at diagnosis is the only way to improve outcomes. Referral to gynecologic oncology at diagnosis of adnexal mass is recommend by guidelines from every major…
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
- Trial name
- NCT06451263
- Testing
- Nudge
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Ectopic Pregnancies
Adnexal Mass After Methotrexate Treatment for Ectopic Pregnancies
Ectopic pregnancies are a common morbidity in the gynaecological field. Previous work done by our team has shown the benefits of conservative treatment with only BHCG (Beta-Human Chorionic Gonadotropin) monitoring, proving that a…
- Trial name
- NCT03138694
- Testing
- BHCG monitoring
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cancer Debulking, Enlarged Uterus
Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy
To determine if opioid consumption postoperatively among patients undergoing non-emergent laparotomy by the gynecologic oncology service who receive intrathecal morphine with intraoperative lidocaine (IML) infusion are lower than…
- Conditions
- Cancer Debulking, Enlarged Uterus, Fibroid Uterus, Adnexal Mass
- Trial name
- NCT05017246
- Testing
- Bupivacaine, Morphine, Lidocaine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Washington University School of Medicine
Ovarian Cancer
Clinician Nudge to Referral of Adnexal Masses to Gynecologic Oncology
The goal of this study is to test the effectiveness of clinician nudges on referrals to gynecologic oncology in patients with suspected ovarian cancer.
- Trial name
- NCT07078409
- Testing
- Nudge
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Gynecologic Disease, Adnexal Mass
Assessment of Women's Sexual Quality of Life After Benign Adnexal Surgery Using vNOTES Approach
Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a recent innovation in minimally invasive surgery which has already proven its non-inferiority to conventional abdominal laparoscopy (CAL) for hysterectomy…
- Conditions
- Gynecologic Disease, Adnexal Mass, Adnexal Cyst, Sexuality
- Trial name
- NCT05761275
- Testing
- Elective cystectomy, Elective oophorectomy, Elective salpingectomy
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- Jean Dubuisson
Patient With Sonographically Indeterminate or Complex Adnexal Mass
ADNEXMR Scoring System: Impact of an MR Scoring System on Therapeutic Strategy of Pelvic Adnexal Masses
Background : About 25% of adnexal masses remain indeterminate after transvaginal ultrasonography, as evidenced by the published literature.
- Trial name
- ASCORDIA01 (NCT02664597)
- Testing
- ADNEXMR Scoring System, Standard strategy
- Where
- France
- Volunteers
- 377 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Demographic Findings, Presenting Symptoms on First Hospital Visit
Clinical Characteristics of Patients Under the Age 21 Years Who Underwent Gynecological Surgery
Young patients with adnexal lesions may have variable presenting symptoms. In this study, we reviewed the clinical characteristics of young Korean patients who took the operation in university hospital with adnexal lesions over…
- Conditions
- Demographic Findings, Presenting Symptoms on First Hospital Visit, Preoperative Radiologic Findings, Operation Method
- Trial name
- NCT00928369
- Volunteers
- 494 people
- Sponsor
- Samsung Medical Center
Ovarian Neoplasms
Gynacological Imaging Reporting and Data System in Ovarian Masses by Ultrasonography
Ovarian masses are common problems in clinical practice. Sonography is considered the firstline imaging technique for discriminating between malignant and benign lesions, and it has been shown to be useful for determining optimal…
- Trial name
- NCT03175991
- Testing
- ultrasonography
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Assiut University