Clinical trials: Adnexal Masses
Ovarian Cancer
Contrast-Enhanced Ultrasonography in Diagnosing Early-Stage Ovarian Cancer in Patients With an Adnexal Mass Undergoing Surgery to Remove the Ovary
RATIONALE: New diagnostic procedures, such as contrast-enhanced ultrasonography, may be an effective method of finding ovarian cancer.
- Trial name
- NCT00626873
- Testing
- Definity, medical chart review
- Where
- 3 sites in United States
- Volunteers
- 67 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gynecology
IOTA Versus Pattern Recognition Method in Diagnosis of Ovarian Masses
To compare between the efficacy of IOTA simple rules and pattern recognition method in the differentiating between benign and malignant adnexal masses
- Trial name
- NCT02800031
- Testing
- Transvaginal ultrasonography
- Where
- Egypt
- Volunteers
- 396 people
- Sponsor
- Woman's Health University Hospital, Egypt
Adnexal Mass
Contrast-Enhanced Subharmonic Ultrasound Imaging in Improving Characterization of Adnexal Masses in Patients Undergoing Surgery
This pilot clinical trial studies how well contrast-enhanced subharmonic ultrasound imaging works in improving the characterization of adnexal masses in patients undergoing surgery.
- Trial name
- NCT03297112
- Testing
- Perflutren Lipid Microspheres, Contrast-Enhanced Subharmonic Ultrasound Imaging
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Adnexal Masses
Machine Learning Algorithms Incorporating Radiomic Ultrasound Features
Adnexal masses represent a frequent clinical finding and their preoperative characterization remains challenging. Accurate discrimination between benign and malignant adnexal masses is essential to optimize patient management…
- Trial name
- R-IOTA (NCT07793201)
- Where
- Italy
- Volunteers
- 12,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Adnexal Mass
Natera Ovarian Cancer Detection Assay
The purpose of this study is to enroll participants who present with an adnexal mass on imaging to develop a non-invasive ovarian cancer assay to distinguish between malignant and benign masses.
- Trial name
- NCT03485651
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Natera, Inc.
Ovarian Cancer
Prospective Evaluation of the Role of MRI in Ovarian Masses During Pregnancy
Ovarian cancer represents 7% of all cancers in pregnant women. Characterizing an ovarian mass during pregnancy is essential to avoid unnecessary treatment and if treatment is required, to plan it accordingly.
- Trial name
- PROM-P (NCT06635837)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ovarian Tumor
Contrast-Enhanced Ultrasound Ability in the Characterization of Ovarian Masses
This study intends to assess the ability of contrast-enhanced ultrasound in the detection of benign and malignant ovarian masses compared to unenhanced ultrasound.
- Trial name
- NCT00248820
- Testing
- Contrast-enhanced ultrasound
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Adenopathy, Uterine Fibroids
A Clinical Study on the Feasibility and Safety of Abdominal Endoscopic Single-port Surgery System to Assist Gynecological Day Surgery
In this study, a prospective study is used to select patients who will undergo intra-abdominal endoscopic single-port surgery system for benign gynecological diseases from February 2025 to December 2026 in the Second Affiliated…
- Conditions
- Adenopathy, Uterine Fibroids, Ovarian Cysts, Adnexal Mass
- Trial name
- NCT06828419
- Testing
- Domestic single-port laparoscopic surgery system
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Postoperative Pain
Transumbilical Versus Lateral Transabdominal Removal of Benign Adnexal Masses Via Laparoscopy
In cases of benign adnexal mass laparoscopic surgery, women were randomized to two groups: transumbilical vs. transabdominal removal.
- Trial name
- NCT02704663
- Testing
- Transumbilical removal of specimen via laparoscopy, Lateral transabdominal removal of specimen via laparoscopy
- Where
- Finland
- Volunteers
- 42 people
- Sponsor
- Helsinki University Central Hospital
Ovarian Carcinoma, Ovarian Cancer
Study Into a New Diagnostic Tool (Simple Ultrasound-based Rules) in Patients With Adnexal Masses
This study is performed to compare the diagnostic performance and cost-effectiveness of different diagnostic methods for differentiating benign from malignant adnexal (ovary or Fallopian tube) masses: the Risk of Malignancy Index…
- Conditions
- Ovarian Carcinoma, Ovarian Cancer, Ovarian Mass, Ovarian Cyst
- Trial name
- SUBSONiC (NCT02218502)
- Testing
- Ultrasound by general gynaecologist, Ultrasound by an expert ultrasonographist, DW-MRI
- Where
- 5 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Maastricht University Medical Center
Pelvic Cancer, Ovarian Cancer
Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses.
In a transvaginal tru-cut biopsy, guided by ultrasound, a needle is inserted through the vaginal wall into a pelvic lesion and a few pieces of tissue are obtained for examination.
- Conditions
- Pelvic Cancer, Ovarian Cancer, Cervical Cancer, Uterus Cancer
- Trial name
- NCT05610501
- Testing
- Ultrasound guided tru-cut biopsy
- Where
- 4 sites in Belgium, Czechia and 2 more
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ovarian Cyst
Assessment of Ovarian Cysts Using Machine Learning
The study aims at creating a prediction model using machine learning algorithms that is capable of predicting malignant potential of ovarian cysts/masses based on patient characteristics, sonographic findings, and biochemical…
- Trial name
- OCID (NCT05342298)
- Testing
- prediction model
- Where
- 2 sites in Egypt
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ovarian Cysts, Ovarian Cancer
Radiomics and Machine Learning in the Diagnosis of Ovarian Masses
The correct differential diagnosis between benign and malignant adnexal masses is the main goal of preoperative ultrasound diagnostics and is very important to plan the correct treatment for the patient in terms of surgical team…
- Trial name
- Multi-AROMA (NCT06342934)
- Testing
- Ultrasound
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Ovarian Mass, Adnexal Mass
An AI-Assisted Agentic System for Ultrasound Scanning and Diagnosis of Ovarian Lesions
Investigators developed an interactive agentic system designed to guide newly qualified sonographers in ovarian lesion scanning and improve their scanning quality and diagnostic performance toward expert-level standards.
- Trial name
- NCT07801209
- Testing
- non-AI assisted and then AI assisted, AI assisted and then non-AI assisted
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Adnexal Masses
Adnexal Masses : Correlation Between MRI (Magnetic Resonance Imagery) and Anatomopathology
The goal of this study is to correlate the pelvic magnetic resonance imagery characteristics of adnexal masses with their anatomopathological characteristics.
- Trial name
- NCT02275273
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- Brugmann University Hospital
Ovarian Cysts, Pediatric ALL
Management of Ovarian Masses in Pediatric Patients: an Italian Survey
Objectives: The International Ovarian Tumor Analysis (IOTA) provides a specific terminology for adult ovarian masses, while, currently, there is no systematic classification for preoperative assessment of adnexal lesions in…
- Conditions
- Ovarian Cysts, Pediatric ALL, Diagnosis
- Trial name
- OvaMa-PEDs (NCT05800613)
- Testing
- Survey
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Surgical Procedure, Unspecified
Comparison of Laparoscopic Adnexal Mass Extraction Via the Transumbilical and Transvaginal Routes
Adnexal masses are a common clinical problem encountered in gynecological practice. Minimally invasive surgery (MIS) for ovarian pathologies has been adopted widely.
- Trial name
- NCT05421117
- Testing
- Laparoscopic adnexal mass extraction
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Ovarian Cancer
Ultrasound RF Data for Discriminating Between Benign and Malignant Ovarian Masses
Ultrasound imaging provides useful information for the characterization of ovarian masses as benign or malignant. The most accurate mathematical model to categorize ovarian masses is the IOTA ADNEX model.This model estimates the…
- Trial name
- RFDATA (NCT06473766)
- Testing
- RF data extraction
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ovarian Cancer
(GI-RADS) in Preoperative Evaluation of Adnexal Masses
prospective study was conducted and performed on 100 women with pelvic pain due to accidently discovered adnexal mass
- Trial name
- NCT06403072
- Testing
- The Gynecologic Imaging-Reporting and Data System (GI-RADS)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Adnexal Mass
New Biomarkers Evaluating Ovarian Cancer
The purpose of this study is to evaluate new biomarkers for patients presenting to a physician for surgery to remove a mass in their pelvis and to continue to evaluate these types of patients using the ROMA algorithm for…
- Trial name
- NCT01466049
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- Fujirebio Diagnostics, Inc.