Clinical trials: Adnexal Tumor
Breast Carcinoma, Colon Carcinoma
Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues
This phase I trial studies a new imaging technique called FAPi PET/CT to determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulate in normal and cancer tissues in patients with non-prostate cancer.
- Conditions
- Breast Carcinoma, Colon Carcinoma, Esophageal Carcinoma, Gastric Carcinoma
- Trial name
- NCT04147494
- Testing
- Computed Tomography, Gallium Ga 68 FAPi-46, Gallium Ga 68-labeled PSMA-11
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Ovarian Cancer
The Assessment of Mesothelin Antigen Specific Immunologic Assays in Ovarian Cancer Patients
Ovarian cancer is the first in mortality rate of the gynecologic malignancies and the overall 5-year survival rate of ovarian cancer is only 20-30%. Besides, the incidence of ovarian cancer increased in recent years in Taiwan.
- Trial name
- NCT00173394
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ovarian Cancer
Adjuvant Whole Abdominal Intensity Modulated Radiotherapy (IMRT) for High Risk Stage FIGO III Patients With Ovarian Cancer
The prognosis for patients with advanced epithelial ovarian cancer remains poor despite aggressive surgical resection and platinum-based chemotherapy.
- Trial name
- OVAR-IMRT-01 (NCT00527631)
- Testing
- whole abdomen irradiation using IMRT
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- Heidelberg University
Breast Cancer, Colon Cancer
CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors
Background: The p53 gene normally helps to stop cancer cells from growing. However, when the p53 gene is mutated or damaged, cancer cells may grow unchecked.
- Conditions
- Breast Cancer, Colon Cancer, Pancreatic Cancer, Sarcoma
- Trial name
- NCT01386502
- Testing
- p53: 264-272 peptide, CT-011
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Epithelial Ovarian Cancer
Tinzaparin And Biomarkers After Neoadjuvant Treatment of Ovarian Cancer
Background: Previous findings have indicated antineoplastic properties of tinzaparin (Innohep®), a commonly used anti-coagulant.
- Trial name
- NCT05284552
- Testing
- Tinzaparin Injectable Solution
- Where
- 8 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- University Hospital, Linkoeping
Polycystic Ovary Syndrome (PCOS), Female Infertility
Comparison of IVF Outcomes Between PPOS and Antagonist Protocols in Women With PCOS
This study aims to compare the outcomes of two ovarian stimulation protocols used in in vitro fertilization (IVF): the progestin-primed ovarian stimulation (PPOS) protocol and the GnRH antagonist protocol.
- Trial name
- PPOS-PCOS-IVF (NCT07394530)
- Testing
- Progestin-Primed Ovarian Stimulation (PPOS), GnRH Antagonist Protocol
- Where
- Vietnam
- Volunteers
- 400 people
- Sponsor
- Hanoi General Hospital (Vietnam)
Breast Neoplasm Female, Early Detection of Cancer
The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI
The purpose of this study is to test the impact of a multilevel decision support intervention on informed decisions about breast MRI among high-risk Black and Latina women.
- Conditions
- Breast Neoplasm Female, Early Detection of Cancer, Hereditary Breast and Ovarian Cancer Syndrome, Magnetic Resonance Imaging
- Trial name
- NCT06892275
- Testing
- Enhanced Usual Care, Decision Support
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Georgetown University
Ovarian Cancer
Photoacoustic Imaging of the Ovary
The purpose of this study is to develop technology to image the ovaries in order to better evaluate ovarian disease and to study how these experimental imaging techniques might work together or separately to improve our ability…
- Trial name
- NCT02110277
- Testing
- PAI/ultrasound Diagnostic Group
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- UConn Health
Ovarian Cancer
The Exploration of Personalized ctDNA Based MRD in the Clinical Significance of Cervical Cancer
This study plans to enroll 80 patients with locally advanced cervical cancer (stage IB-ⅣA) confirmed by histology or cytology (according to the 2018 FIGO staging standard), who are expected to receive surgical resection or…
- Trial name
- NCT06283875
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Geneplus-Beijing Co. Ltd.
Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus
Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery
Study Objectives This study aims to investigate the effects of preoperative stellate ganglion block and intraoperative intravenous dexmedetomidine on postoperative sleep disturbance in patients undergoing laparoscopic gynecologic…
- Conditions
- Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus, Endometriosis, Endometrial Cancer
- Trial name
- NCT07860203
- Testing
- DEX 0.2 μg/kg/h., SGB
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Catherin Zhang
Locally Advanced Cervical Carcinoma, Premature Ovarian Failure
Autologous Heterotopic Fresh Ovarian Graft in Woman With LACC Eligible for Pelvic Radiotherapy Treatment.
Pelvic chemoradiotherapy (CRT) is an effective treatment for Locally Advanced Cervical Cancer (LACC). However, CRT induces premature ovarian failure ceasing the production of ovarian hormones.
- Trial name
- NCT05462379
- Testing
- Ovarian graft
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- MARILIA ALBANEZI BERTOLAZZI
Ovarian Cancer, Epithelial Ovarian Cancer
Heated Intraperitoneal Chemotherapy in Primary Ovarian Cancer Patients
This study will evaluate the use of Heated Intraperitoneal Chemotherapy (HIPEC) for primary treatment of ovarian cancer at the time of surgical debulking, to assess if intravenous (IV) chemotherapy can be started within 42 days…
- Conditions
- Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube Cancer
- Trial name
- NCT03321188
- Testing
- HIPEC, Carboplatin, Paclitaxel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Andrea Jewell
Polycystic Ovary Syndrome, Insulin Resistance
Acupuncture or Metformin for Insulin Resistance in Women With PCOS
The hypothesis is that acupuncture is equally effective as metformin (both treatments combined with lifestyle management) in improving whole body glucose homeostasis in insulin resistant women with polycystic ovary syndrome…
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Hyperandrogenism
- Trial name
- PIAII (NCT02647827)
- Testing
- Lifestyle management, Acupuncture, Metformin
- Where
- 2 sites in China, Sweden
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Polycystic Ovary Syndrome (PCOS)
Effects of Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients
The purpose of this study is to determine whether micronized trans-resveratrol improves clinical (excessive hair, menstrual cycle), endocrine (androgens)and metabolic (lipids, markers of systemic inflammation) in women with…
- Trial name
- NCT01720459
- Testing
- Micronized trans-resveratrol
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Poznan University of Medical Sciences
Ovarian Cancer
Study of Autologous, Metabolically Optimized, CD137+ Tumor-Infiltrating Lymphocytes Followed by Consolidative Oral Cyclophosphamide, Bevacizumab, and Pembrolizumab
Patients with recurrent ovarian cancer will undergo resection of a safely accessible metastatic lesion, from which tumor-infiltrating lymphocytes (TIL) will be cultured, metabolically reprogrammed for metabolic fit T cells, then…
- Trial name
- OVAFIT-TIL (NCT07720180)
- Testing
- Fludarabine, Cyclophosphamide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Polycystic Ovary Syndrome
Clomiphene Stair-Step Protocol for Ovulation Induction in Women With Polycystic Ovarian Syndrome
The objective of our study is to evaluate the efficacy of the clomiphene stair-step protocol to induce ovulation in women with polycystic ovarian syndrome (PCOS) compared to traditional protocol.
- Trial name
- PCOSCCTvUSS (NCT01953796)
- Testing
- clomiphene
- Where
- Iraq
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kufa University
Skin Cancer, Skin Cancer Face
Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery
The purpose of this study is to compare surgical site infection rates for patients treated with Mohs micrographic surgery after bilateral nasal swab with povidone iodine versus standard treatment including the use of a…
- Conditions
- Skin Cancer, Skin Cancer Face, Malignant Cutaneous Adnexal Neoplasm
- Trial name
- NCT06207786
- Testing
- Povidone-Iodine Swabs, Staphylococcus nasal swab, Antibiotic
- Sponsor
- Mayo Clinic
Ovarian Cancer
Evaluation of Response to the Neoadjuvant Chemotherapy for Advanced Ovarian Cancer by Multimodal Functional Imaging
This study evaluates the therapeutic response by modern FMRI and PET techniques with the perspective to exploit multimodal data (fusion MRI/PET).
- Trial name
- IMOVA (NCT02792959)
- Testing
- Functional Imaging previous the second course, Functional Imaging previous the surgery
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Institut Bergonié
Polycystic Ovary Syndrome (PCOS)
Amelioration of Polycystic Ovary Syndrome Related Disorders by Supplementation of Thymoquinone and Metformin
Objective: To investigate the potential benefit of adding Thymoquinone to Metformin in alleviating symptoms of polycystic ovarian syndrome. Methods: 207 overweight and obese PCOS Patients were divided into two groups.
- Trial name
- NCT04852510
- Testing
- Metformin Versus a combination of Metformin and Thymoquinone (TQ)
- Where
- Saudi Arabia
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Saudi German Hospital - Madinah
Malignant Neoplasm of Fallopian Tube
Detection of Chlamydia DNA by Polymerase Chain Reaction in Primary Tubal and Ovarian Cancers Tissues : a Pilot Study
PCR for chlamydia DNA is done in paraffin blocks of cases of primary tubal cancer and is compared to cases of high grade serous ovarian cancer and normal tubes .
- Trial name
- NCT02343510
- Testing
- PCR for chlamydia DNA in primary tubal cancer
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
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