Clinical trials: Adolescence
Asthma
Efficacy and Safety of Omalizumab in Patients With Severe Persistent Asthma
The purpose of this study is to determine the effect of omalizumab, compared to placebo, on clinically significant asthma exacerbation rates in adolescents and adults with asthma.
- Trial name
- NCT00046748
- Testing
- Omalizumab
- Volunteers
- 484 people
- Sponsor
- Novartis Pharmaceuticals
Autism
Safety of L1-79 in Adolescent and Adult Males With Autism
This is a five-arm designed to assess the safety of L1-79 that incorporates 15 prospectively randomized, placebo controlled patients and 5 open label patients at either 100 tid (three times daily) or 200 tid dosing for 28 days.
- Trial name
- NCT02947048
- Testing
- L1-79
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Yamo Pharmaceuticals LLC
Fractures, Bone, Pediatrics
Absorbable Screws to Treat Anterior-Superior Iliac Spine Avulsion Fractures
There is some debate over the best treatment for anterior-superior iliac spine (ASIS) avulsion fractures although conservative treatment can be applied when there are no neurological symptoms.
- Trial name
- NCT03975426
- Testing
- open reduction and internal fixation with fixation by absorbable screws
- Volunteers
- 59 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Adolescents With Scoliosis
Mat-Pilates Exercises on Balance in Adolescents With Scoliosis
The aim of this study is to examine the effects of mat-Pilates exercises on balance and functional capacity in adolescents with scoliosis.
- Trial name
- NCT07638826
- Testing
- Conventional Physical Therapy, Mat-Pilates Exercises
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Adolescence Obesity
Phase Ib Study of Efsubaglutide Alfa Injection in Obese Adolescents
This is a Phase Ib, randomized, double-blind, placebo-controlled clinical study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of Efsubaglutide Alfa Injection following multiple-dose…
- Trial name
- NCT07693426
- Testing
- Efsubaglutide Alfa 5 mg QW, Efsubaglutide Alfa 10 mg QW, Efsubaglutide Alfa 20 mg QW
- Where
- 5 sites in China
- Volunteers
- 36 people
- Sponsor
- Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
Substance Abuse
"Effectiveness of School-based Substance Abuse Prevention Programme Among Adolescents .
The objectives of the study is to 1. "to explore the perception of teachers, parents \& students in the prevention of substance abuse among adolescents". 2.
- Trial name
- NCT06004726
- Testing
- School-based Substance abuse Prevention Programme (SSPP)
- Where
- 3 sites in Nepal
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Manipal College of Nursing
Motor Vehicle Crash Injuries
Teenage Passenger Influences on Driving Performance of Teenage Drivers
This study, conducted at the University of Massachusetts at Amherst, will examine how male teenage driving performance varies in the presence or absence of male teenage passengers.
- Trial name
- NCT00716378
- Testing
- Teen Passenger Presence
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Altitude Training Adaptation, Autonomic Nervous System
Effect of Hot Spring Therapy on Autonomic Nervous System and Exercise Performance During Altitude Training
This randomized controlled trial aims to investigate the effects of balneotherapy (hot spring bathing) on cardiac autonomic nervous system function and exercise performance in healthy athletes undergoing high-altitude training.
- Conditions
- Altitude Training Adaptation, Autonomic Nervous System, Hydrotherapy, Exercise Performance
- Trial name
- NCT07608887
- Testing
- Control Group：Natural Recovery, Hot water immersion group, hot spring immersion group
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Anxiety, Depression
Sexual and Gender Minority Youth (SGMY) and Online Interventions to Increase Help-seeking for Anxiety and/or Depression
the investigators will use 4 technology based tools (combinations of youtube videos, links to online resources, tiktok videos, and other media) in a study of 96 Sexual and Gender Minority Youth (SGMY) to determine the…
- Conditions
- Anxiety, Depression, Adolescent Behavior, Sexual and Gender Minorities
- Trial name
- NCT06083987
- Testing
- Intersectionality and Identity, Confidentiality, Educating Your Community
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Allergic Rhinitis Due to Dust Mite
Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis in Adolescents and Children
The purpose of this study is to assess the efficacy of one dose of sublingual immunotherapy (SLIT) administered to children and adolescents as allergen-based tablets once daily over a period of 24 months over 3 years compared to…
- Trial name
- NCT01199133
- Testing
- 300 IR house dust mites allergen extract tablet
- Volunteers
- 471 people
- Sponsor
- Stallergenes Greer
Childhood Obesity
Motivational Interviewing for Weight Loss
The investigators studied the effect of motivational interviewing (MI) on self-efficacy, health behaviors, and health outcomes in overweight children and adolescents (ages ranging from 10 to 18 years).
- Trial name
- NCT01246349
- Testing
- Motivational Interviewing (Treatment Group), Social Skills Training (Control Group)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Post-traumatic Stress Disorder, Alcohol Abuse
Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
Recent needs assessments suggest that difficulties exist in care coordination between emergency medical services (EMS) systems and primary care for injured adolescents with alcohol problems and post-traumatic stress disorder…
- Conditions
- Post-traumatic Stress Disorder, Alcohol Abuse, Alcohol Dependence
- Trial name
- ATRSCC (NCT00619255)
- Testing
- Adolescent Trauma Support Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Washington
Functional Disability
User Satisfaction of an Instrumented Standing Frame
Standing frames have existed for a long time and are well-established medical devices used to allow weight bearing in standing for persons who are unable to stand independently.
- Trial name
- NCT06033885
- Testing
- PONDUS®
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Southern Denmark
Autism Spectrum Disorder, Obesity, Childhood
Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
The objective of this proposed study is to collect initial efficacy data on a telehealth parent-based behavioral program for children with autism and overweight or obesity (PBT-A), compared with health education (HE).
- Conditions
- Autism Spectrum Disorder, Obesity, Childhood, Autism
- Trial name
- FRESH-A (NCT05741840)
- Testing
- PBT-A, Health Education (HE)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Development; Unilateral
The Degree, Development and Interrelationship of Structural and Functional Asymmetry in (Pre)Adolescent Elite Tennis Players
Humans generally develop a preferred upper and lower extremity. Due to repetitive uneven loading, this gradually results in structural (e.g. increased bone and muscle mass) and functional (e.g.
- Trial name
- AsymTen (NCT03128814)
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Laurent Chapelle
HIV Infections
Affect Management for Early Adolescents
Adolescents are at risk for HIV because of sexual and drug use behavior initiated during early adolescence, and those with mental health problems appear to be particularly susceptible.
- Trial name
- NCT01197404
- Testing
- Affect Management, General Health Promotion
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Sialorrhea, Neurodevelopmental Disorders
Double-blind, Placebo-controlled, Randomized Clinical Trial Comparing the Efficacy and Safety of Sialanar Plus orAl rehabiLitation Against Placebo Plus Oral Rehabilitation for chIldren and Adolescents With seVere Sialorrhoea and Neurodisabilties,
Double blind, placebo-controlled, randomised trial, multicentre in France with open-label tolerability phase. The double-blind placebo-controlled study duration will be scheduled for 3 months with the final visit of the…
- Trial name
- SALIVA (NCT04873115)
- Testing
- Sialanar, Oral Rehabilitation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Proveca Pharma Limited
Diabetes Mellitus, Type 2
Prevention of Type 2 Diabetes Mellitus in Children
This is a pilot study to examine the short-term effects of supervised exercise on metabolic risk factors for type 2 diabetes mellitus in children from a population that is at high risk for this disease.
- Trial name
- NCT00073268
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Adolescent Health, Nutrition Behavior
The Effect of an Artificial Intelligence-Supported Health Promotion Application on the Nutrition, Exercise and Sleep Habits of Adolescents
The goal of this clinical trial is to learn if the "Smart Nurse" artificial intelligence-supported mobile application improves nutrition, exercise, and sleep behaviors in high school students aged 14-18 years.
- Conditions
- Adolescent Health, Nutrition Behavior, Physical Activity, Sleep Quality
- Trial name
- SN-ADOL-RCT (NCT07524582)
- Testing
- Smart Nurse Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Pes Plano Valgus
Arthroereisis With Corrective Osteotomy Versus Arthroereisis Alone in Management of Symptomatic Flexible Pes Planovalgus in Adolescents
Arthroereisis ,corrective osteotomies, flexible pes planovalgus, adolescents
- Trial name
- NCT06763523
- Testing
- arthroereisis of the subtalar joint
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University