Clinical trials: Adolescent Cannabis Use Disorder
Cannabis Use Disorder, Mild, Cannabis Use Disorder, Moderate
Pilot Test of Parent-Focused Cannabis-Related Actions and Practices Intervention for Adolescent Marijuana Abuse
The randomized clinical trial involves the pilot-testing of a theory-guided, empirically based, and low-cost intervention designed for legal medical marijuana-using parents to enhance parenting behaviors that limit youth exposure…
- Trial name
- CAP (NCT04923230)
- Testing
- Cannabis Actions and Practices Resource for Parents
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Cannabis Use
Feasibility and Acceptability of the Cannabis Awareness and Prevention Toolkit
The Stanford Smart Talk Cannabis Awareness and Prevention Curriculum includes 5 lessons, each providing activities, online quiz games, and worksheets in addition to presentations, resources, and other materials aimed at…
- Trial name
- NCT05521321
- Testing
- Stanford Smart Talk Cannabis Awareness and Prevention curriculum
- Where
- United States
- Volunteers
- 658 people, healthy volunteers welcome
- Sponsor
- Stanford University
Alcohol Drinking, Marijuana
Brief Interventions With Text Messaging to Reduce Adolescent Alcohol and Marijuana Use
This study tests the feasibility of an intervention to prevent risky alcohol or marijuana use that adds a 4-week course of tailored text messaging to a brief motivational intervention for 13-18-year-old adolescents.
- Trial name
- STAR (NCT03401333)
- Testing
- Text Messaging and Brief Negotiation Interview
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Drinking, Cigarette Smoking
Brief Voluntary Alcohol and Drug Intervention for Middle School Youth
We are currently working in 16 middle schools across Los Angeles, Santa Monica and Torrance to test out a voluntary after school program called Project CHOICE, which focuses on helping students decrease their alcohol and drug…
- Conditions
- Alcohol Drinking, Cigarette Smoking, Marijuana Smoking
- Trial name
- CHOICE (NCT01081119)
- Testing
- Project CHOICE
- Where
- United States
- Volunteers
- 6,455 people
- Sponsor
- RAND
Alcohol Drinking, Marijuana Smoking
Motivation and Skills for Delta-9-tetrahydrocannabinol/Ethanol (THC/ETOH+) Teens in Jail
This study will focus on treating substance abusing incarcerated teens using individually administered Motivational Interviewing (MI) followed by group Cognitive Behavior Therapy (CBT).
- Trial name
- SMART (NCT00506753)
- Testing
- MI/CBT, RT/SU
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Cannabis Use, THC
Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults
The goal of this interventional study is to determine the impact of high potency THC product use on cognitive function of young adults aged 21-25.
- Conditions
- Cannabis Use, THC, Marijuana Use, Cognitive Impairment
- Trial name
- THC-YA (NCT06077292)
- Testing
- 15% THC Potency Reduction, 35% THC Potency Reduction
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cannabis Use
Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder
This project seeks to learn more about the effects of cannabis use on the endocannabinoid system and endogenous opioid systems in adolescents to address a fundamental gap in knowledge and identify biomarkers that may help…
- Trial name
- NCT05396638
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Adolescent Cannabis Use Disorder
Biofeedback for Adolescent Cannabis Use Disorder
The aims of this study are: 1) to estimate the effect size of HRV biofeedback for stress in adolescents undergoing cognitive behavioral therapy (CBT) for cannabis use disorder (primary outcome: Perceived Stress Scale) and 2) to…
- Trial name
- NCT02059083
- Testing
- Heart rate variability biofeedback, CBT
- Sponsor
- Denver Health and Hospital Authority
Drug Use
Gender-Responsive Drug Use Treatment for Juvenile Justice Girls
Girls in the juvenile justice system have unique developmental pathways to drug use and co-occurring risk (e.g., HIV/STI) behaviors that have typically not been considered or tested in order to identify evidence-based…
- Trial name
- NCT02293057
- Testing
- VOICES Group, Girl Health Group
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Substance Use, Substance-Related Disorders
Clinician Practice Companion to Address Youth Substance Use
Substance use, including the use of opioids, cannabis, and other drugs, is common among adolescents and young adults, and overdose has become a leading cause of death among youth in Canada and the United States.
- Conditions
- Substance Use, Substance-Related Disorders, Adolescent Substance Use, Cannabis Use
- Trial name
- NCT07725289
- Testing
- Practice Companion
- Where
- 5 sites in United States, Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cannabis Use Disorder
Assessment of the Effectiveness of an Integrative Therapy for Cannabis Misuse in Adolescents
The primary objective of this study is to evaluate an Integrative Therapy for Adolescent Cannabis Use (TIMCA), integrating elements of Motivational Interviewing (MI), Cognitive Behavioral Therapies (CBT) and an Attachment-Based…
- Trial name
- TIMCA (NCT05765409)
- Testing
- TIMCA, Treatment as Usual
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier St Anne
AOD Use, Abuse, and Dependence, Depression
Treatment for Teens With Alcohol Abuse and Depression
The investigators will recruit adolescents with alcohol or cannabis abuse and clinically significant depression. All participants will receive 12 sessions of an evidence-based treatment for alcohol abuse, Motivation Enhancement…
- Trial name
- T-TAAD (NCT02227589)
- Testing
- MET/CBT-12, CBT-D, D-TAU
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- Duke University
Substance-related Disorders, Alcohol-Related Disorders
LaunchPad: Supporting Healthy Decisions and Preventing Drug Use After High School
LaunchPad is an online substance use prevention program for high school seniors. The program is designed to help seniors develop skills and make informed decisions as they transition from high school to young adulthood.
- Conditions
- Substance-related Disorders, Alcohol-Related Disorders, Tobacco Use Disorder, Marijuana Use
- Trial name
- NCT07655609
- Testing
- Introduction, Norms re: Protective Behavior Strategies (PBS), Life Skills
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Prevention Strategies, LLC
Marijuana Abuse
Efficacy of Contingency Management in the Treatment of Adolescents With Cannabis Use Disorders
Cannabis use among Spanish adolescents has been increasing in the last decade. It has been related to poor school achievement, delinquency, substance use and psychiatric disorders.
- Trial name
- NCT00878852
- Testing
- Standard treatment, Standard Treatment Plus Contingency Management Program
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Clinic of Barcelona
Bipolar Disorder, Cannabis-Related Disorder
Efficacy Study of Quetiapine Plus Topiramate for Reducing Cannabis Consumption and Bipolar Mania
The objectives of this study are to determine whether this treatment may be useful for reducing cannabis consumption; reducing symptoms of bipolar mania; and weight mitigation therapy for individuals on psychopharmacotherapy.
- Trial name
- NCT00393978
- Testing
- Quetiapine and Topiramate
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Cincinnati
Mental Illness, Schizophrenia
Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use
Severe mental illness (SMI) refers to the most burdensome psychiatric conditions. The need to pre-empt the onset of SMI is pressing because once SMI develops, quality of life is poor and available treatments have limited…
- Conditions
- Mental Illness, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- IMAGINE (NCT03601026)
- Testing
- Genetic counselling
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Nova Scotia Health Authority
Marijuana Abuse
A Real-time, Contextual Intervention Using Mobile Technology to Reduce Marijuana Use in Youth
The purpose of this study is to further develop and test the Momentary Self-Monitoring and Feedback + Motivational Enhancement Therapy (MOMENT) intervention, a real-time, contextual intervention to reduce marijuana use among…
- Trial name
- MOMENT (NCT01762696)
- Testing
- MET, MOMENT
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Boston Children's Hospital
Substance Abuse, Juvenile Delinquency
The Community Youth Development Study: A Test of Communities That Care
The Community Youth Development Study is an experimental test of the Communities That Care (CTC) prevention planning system. It has been designed to find out if communities that were trained to use the CTC system improved public…
- Conditions
- Substance Abuse, Juvenile Delinquency, Sexual Behavior, Criminal Behavior
- Trial name
- CYDS IV (NCT01088542)
- Testing
- Communities That Care
- Where
- United States
- Volunteers
- 52,323 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV/AIDS
Project RAP: Family-based HIV Prevention in the Juvenile Drug Court
The purpose of this project is to compare the effect of a family-based HIV prevention program to the effect of an adolescent-only health promotion program on adolescent HIV risk and marijuana use among adolescents enrolled in the…
- Trial name
- Project RAP (NCT01403298)
- Testing
- Family-Based HIV prevention, Adolescent Only Health Promotion
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dual Diagnosis, Risk Youth
Virtual Reality (VR-GINSO) as an Complement to Intervention for Alcohol and Cannabis Use in Youth in Residential Care
The goal of this RCT is to evaluate the effects of a virtual reality intervention on self-efficacy regarding alcohol and cannabis use among at-risk youth in various residential mental health treatment centers who have…
- Conditions
- Dual Diagnosis, Risk Youth, Antisocial Behavior
- Trial name
- VR-GINSO (NCT07834606)
- Testing
- Virtual Reality, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad Francisco de Vitoria