Clinical trials: Adolescent Depression
Adolescent Behavior, Adolescent - Emotional Problem
Teachers Leading the Front Lines - Adolescent
Purpose: The purpose of this research is to pilot test a novel, alternative, potentially sustainable system of teacher-delivered, task-shifted adolescent mental health care.
- Conditions
- Adolescent Behavior, Adolescent - Emotional Problem, Mental Health Issue, Psychosocial Functioning
- Trial name
- TeaLeaf-A (NCT06248203)
- Testing
- Tealeaf-Mansik Swasta (Tealeaf) as adapted for Adolescents, Enhanced Usual Care (EUC)
- Where
- India
- Volunteers
- 216 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder (MDD), Adolescent Depression
Predictors of rTMS and Group Therapy Efficacy in Adolescent Depression
This study aims to identify baseline predictors of treatment efficacy in adolescents with Major Depressive Disorder (MDD) undergoing a combined intervention of repetitive transcranial magnetic stimulation (rTMS) and group…
- Trial name
- NCT07283419
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Group Cognitive Behavioral Therapy (CBT)
- Where
- China
- Volunteers
- 163 people
- Sponsor
- The First Hospital of Hebei Medical University
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
Anxiety, Depression
Sexual and Gender Minority Youth (SGMY) and Online Interventions to Increase Help-seeking for Anxiety and/or Depression
the investigators will use 4 technology based tools (combinations of youtube videos, links to online resources, tiktok videos, and other media) in a study of 96 Sexual and Gender Minority Youth (SGMY) to determine the…
- Conditions
- Anxiety, Depression, Adolescent Behavior, Sexual and Gender Minorities
- Trial name
- NCT06083987
- Testing
- Intersectionality and Identity, Confidentiality, Educating Your Community
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Type2 Diabetes, Type 2 Diabetes Mellitus
Depression & Insulin Sensitivity in Adolescents
There has been a rise in type 2 diabetes (T2D) rates in adolescents, disproportionately in girls from disadvantaged racial/ethnic groups.
- Conditions
- Type2 Diabetes, Type 2 Diabetes Mellitus, Insulin Sensitivity, Insulin Resistance
- Trial name
- NCT03263351
- Testing
- Cognitive-behavioral therapy group, Health education group
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Colorado State University
Adolescent Suicide, Adolescent Depression
Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine
The purpose of this study is to determine if intravenous ketamine reduces suicidal thinking compared to an active placebo (midazolam) in adolescents who have treatment resistant depression and a recent history of a suicide event…
- Trial name
- NCT04613453
- Testing
- Ketamine Infusion, Midazolam Infusion
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Yale University
Depression, Adolescent Depression
"Culturally Adapted CBT for Depression in Arab and Asian Adolescents in the UAE (CA-CBT)"
This study evaluated the effectiveness of a culturally adapted form of Cognitive Behavioural Therapy (CA-CBT) for reducing depression among Arab and Asian adolescents in the United Arab Emirates (UAE).
- Conditions
- Depression, Adolescent Depression, Mental Health, Psychological Stress
- Trial name
- CA-CBT (NCT07109973)
- Testing
- Culturally Adapted Cognitive Behavioural Therapy (CA-CBT), Treatment-as-Usual (TAU)
- Where
- United Arab Emirates
- Volunteers
- 175 people
- Sponsor
- Bath Spa University Academic Centre RAK
Adolescent Depression
A Hybrid Psychological Intervention for Depression in Adolescents
This multi-center, randomized controlled trial was conducted to evaluate the efficacy and long-term effects of a novel hybrid psychological intervention, which combines Resilience Theory with the Satir Model, for adolescents…
- Trial name
- NCT07104851
- Testing
- Resilience-Satir Hybrid Intervention, Treatment as Usual (TAU)
- Where
- China
- Volunteers
- 420 people
- Sponsor
- The First Hospital of Hebei Medical University
Adolescent Depression
Resilience and Satir Model Training for Adolescent Depression
This randomized controlled trial aims to assess the effectiveness of an intervention combining resilience theory with Satir model nursing skills training compared to routine nursing care for adolescents with depression.
- Trial name
- NCT07063485
- Testing
- Resilience Theory and Satir Model Nursing Skills Training, Routine Nursing Intervention
- Where
- China
- Volunteers
- 182 people
- Sponsor
- The First Hospital of Hebei Medical University
Insomnia, Depression
Digital Mood-enhanced CBT-I to Improve Depressive Symptoms in Adolescents
Emerging encouraging evidence showed that sleep focused treatment can simultaneously improve sleep and depression in adult with comorbid conditions.
- Conditions
- Insomnia, Depression, Adolescent
- Trial name
- NCT06358898
- Testing
- Standard dCBT-I, Modified Mood enhanced CBT-I (M-dCBT-I)
- Where
- Hong Kong
- Volunteers
- 343 people
- Sponsor
- Chinese University of Hong Kong
Depression, Cancer
Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit
The investigators developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression.
- Conditions
- Depression, Cancer, Adolescent, Young Adult
- Trial name
- ASCENT (NCT06420193)
- Testing
- AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- East Carolina University
Suicide Attempt, Depression
Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain
What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain.
- Conditions
- Suicide Attempt, Depression, Adolescent Mental Health, Self-Harm
- Trial name
- NCT06996054
- Testing
- Multifaceted School-Based Mental Health and Suicide Prevention Program
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Non-suicidal Self-injury (NSSI), Adolescent
Clinical and Psychosocial Characteristics of Adolescent Patients With Non-Suicidal Self-Injury
The overall objective of this study is to explore the social and clinical psychological characteristics of adolescents with depression accompanied or not accompanied by non-suicidal self-harm. This is an observational study.
- Conditions
- Non-suicidal Self-injury (NSSI), Adolescent, Depression
- Trial name
- NCT06885749
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Adolescent, Depression - Major Depressive Disorder
Efficacy and Mechanism of Transcranial Temporal Interference Stimulation (tTIS) in the Treatment of Adolescent Depression
This trial is a single-center, single-blind, randomized, sham-stimulation controlled clinical trial. The primary objective of the trial is to detect the targeted effect of tTIS on the nucleus accumbens of adolescent depression…
- Trial name
- NCT06902064
- Testing
- Transcranial temporal interference stimulation
- Volunteers
- 30 people
- Sponsor
- Xijing Hospital
Depression - Major Depressive Disorder, Adolescent
Mood And Kids diEt (MAKE-It) Pilot Trial
This study is being done to examine the feasibility, including recruitment, retention and acceptability of a randomized controlled trial of a personalized dietary intervention in adolescents with depression.
- Trial name
- MAKE-IT pRCT (NCT06716034)
- Testing
- Personalized Nutrition Plan and Support
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Suicide Awareness, Suicidal Ideation
"Youth Aware of Mental Health" in Galicia
The goal of this interventional study is to assess the effectiveness of the universal suicide prevention program "Youth Aware of Mental Health" in 3rd-year secondary education students in Galicia.
- Conditions
- Suicide Awareness, Suicidal Ideation, Suicide, Attempted, Depressive Symptoms
- Trial name
- YAM (NCT06251037)
- Testing
- Youth Aware of Mental Health in Galicia
- Where
- 68 sites in Spain
- Volunteers
- 4,453 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Depression, Adolescent - Emotional Problem
RCT of a Brief Video Intervention Targeting Peer Inclusion to Reduce Depression-related Stigma in Adolescents
The goal of this study is to test the efficacy of a brief video intervention emphasizing peer inclusion on depression-related stigma and stigma outcomes (e.g., help seeking attitudes, secrecy) among adolescents 14-18.
- Conditions
- Depression, Adolescent - Emotional Problem, Stigma, Social, Help-Seeking Behavior
- Trial name
- NCT06360107
- Testing
- brief video
- Where
- United States
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Assessment of Depression, Anxiety and ADHD Among Children and Adolescents With Congenital Heart Disease
Assessment of Depression, Anxiety and ADHD Among Children and Adolescents With Congenital Heart Disease.
Congenital heart disease (CHD) is the most common birth defect, affecting ∼1% of all live births.The spectrum of CHD is wide, ranging from simple (not requiring immediate or possibly any surgical intervention) to severe or…
- Trial name
- Psychiatricy (NCT06836076)
- Volunteers
- 50 people
- Sponsor
- Assiut University
Depression, Adolescent Behavior
Evaluation of an Asynchronous Remote Communities Approach to Behavioral Activation for Depressed Adolescents
The goal of this clinical trial is to learn if a digital health intervention, called "ActivaTeen," improves depression treatment for teenagers with depression.
- Trial name
- NCT06786247
- Testing
- ActivaTeen, Behavioral Activation
- Volunteers
- 70 people
- Sponsor
- University of Washington
Obesity and Obesity-related Medical Conditions, Menstrual Pain
Quality of Life Variations Among Adolescent Females Following Virtual Reality Games Approach
to compare the effects of virtual reality games, aerobic exercise, and dietary modifications on Quality of Life among adolescent females.
- Conditions
- Obesity and Obesity-related Medical Conditions, Menstrual Pain, Adolescent Obesity, Body Fat Composition
- Trial name
- NCT06604429
- Testing
- Aerobic exercise, Diet Advice, Virtual reality exercise
- Where
- 3 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Mina Atef Georgui Elias