Clinical trials: Adolescent Depression
Depression, Drug Use
Families With Pride ("Familias Con Orgullo").
This study will evaluate the effects of a parenting intervention for Hispanic sexual minority youth in preventing/reducing drug use and depressive symptoms.
- Trial name
- NCT06057337
- Testing
- Families with Pride ("Familias con Orgullo")
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- University of Miami
Generalized Anxiety Disorder, Social Phobia
Effectiveness of Six Sessions CBT for Adolescents With Emotional Problems in Community Clinics
Background: There is need for more effectiveness studies concerning treatment of emotional symptom problems indicating anxiety and depression in adolescents.
- Conditions
- Generalized Anxiety Disorder, Social Phobia, Agoraphobia, Depression
- Trial name
- SMART (NCT02150265)
- Testing
- SMART manual cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 163 people
- Sponsor
- University of Tromso
Depression
Reaching Out to Adolescents With Depression
Major Depression is one of the most common mental health disorders in adolescence and is associated with significant impairments in development and functioning.
- Trial name
- ROAD (NCT01140464)
- Testing
- Collaborative care, Enhanced Usual Care
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Depression, Bullying
Intervention Based on Implicit Theories of Personality: Effects on Depression and Bullying
This study evaluates the efficacy of an intervention based on the Implicit Theories of Personality (ITP) in Spanish adolescents.
- Trial name
- ITP (NCT03481699)
- Testing
- Incremental theory of personality, Educational Intervention
- Volunteers
- 882 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Major Depressive Disorder (MDD), Probiotic Intervention
Sertraline Combined With Multi-Strain Probiotics for Adolescent Depression
The objective of this clinical trial is to evaluate the efficacy and safety of sertraline combined with multi-strain probiotics in adolescents aged 12-18 with major depressive disorder.
- Trial name
- NCT07645157
- Testing
- Sertraline
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Anxiety, Depression
Using Neuroimaging to Understand Children's Mental Health and Treatment Outcomes
The study will compare the impact of Child STEPs versus usual school-based therapy on neural and companion behavioral measures of self-regulation.
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03112265
- Testing
- Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System, Treatment as usual
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Harvard University
Depression
EEG-Triggered rTMS and Group Therapy for Adolescents With Depression and Self-Harm
This randomized controlled trial aims to evaluate the efficacy of real-time EEG-triggered repetitive transcranial magnetic stimulation (rTMS) combined with group therapy versus rTMS alone in adolescents (aged 12-18 years)…
- Trial name
- NCT07047534
- Testing
- Real-time EEG-triggered Repetitive Transcranial Magnetic Stimulation (rTMS), Group Therapy
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The First Hospital of Hebei Medical University
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety, Depressive Symptoms
A Single-Session Intervention for Adolescents and Young Adults With Internalizing Problems
With the increasing number of adolescents and young adults (AYA) experiencing depression and anxiety, paired with the lack of time, access, and funding towards social services, AYA need a mental health intervention that is…
- Trial name
- NCT05826392
- Testing
- Adolescent/Young Adult Self-Administered Web-Based Single-Session Intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Depression in Adolescence
Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function
This research will use biobehavioral approaches to generate understanding about the linkages between sleep duration and timing, stressful life events, and depressive symptoms in adolescents, with a long-term aim of developing…
- Trial name
- MoDA (NCT05691439)
- Testing
- Sleep extension and advance, Regular sleep duration and timing
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Oregon
Depression
Effect of Coping With Stress Program to Depression, Anxiety, Brain Functions in Adolescent at High-Risk for Depression
Depression is one of the leading diseases that cause disability, disease burden and threaten public health all over the world. In addition to the economic burdens brought on by depression, it also leads to many individual…
- Trial name
- NCT03779477
- Testing
- Coping with Stress Course
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Dokuz Eylul University
Depression
The Relationships of Cyber-bullying and Bullying With Mental Health Among Taiwanese Adolescents
Background and significance: Though the problem of bullying among adolescents is evidently increasing and of a serious social concern, it is often undetected until serious outcomes have surfaced.
- Trial name
- NCT02860832
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Depressive Disorder, Depression
Evaluation of the Naturalistic User Experience of the Website "Ich Bin Alles"
Using a multi-method approach, the aim of this study is to investigate the naturalistic user experience and acceptance of the German website "ich bin alles".
- Conditions
- Depressive Disorder, Depression, Depression in Children, Depression in Adolescence
- Trial name
- NCT06668701
- Testing
- "ich bin alles"
- Where
- Germany
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Anxiety, Traumatic Stress
Personalizing Mental Health Treatment for Youth and Families
Incompatibility between evidence-based treatments (EBTs) and the cultural values, practices, and minoritized experiences of Latine youth and families contributes to racial-ethnic disparities in mental health treatment engagement…
- Conditions
- Anxiety, Traumatic Stress, Disruptive Behavior, Depression
- Trial name
- NCT07425366
- Testing
- Culturally Responsive Assessment, Formulation, and Treatment Tool (CRAFTT), Cultural Formulation Interview, Modular Approach to Therapy for Children
- Volunteers
- 64 people
- Sponsor
- University of Oregon
Depression in Adolescence
Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents With Depression
Despite the prevalence and significant public health concern over depression among adolescents, up to 40% of depressed adolescents do not respond to first-line antidepressants (herein termed treatment non-response, TNR).
- Trial name
- TIGER (NCT05329441)
- Testing
- Trier Social Stress Test (TSST)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of California, Los Angeles
Major Depressive Disorder
Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder
The primary hypothesis is that compared to placebo, 10g of daily creatine monohydrate for eight weeks will be associated with significant increases in frontal lobe phosphocreatine and beta-nucleoside triphosphate (β-NTP)…
- Trial name
- NCT02134808
- Testing
- Creatine
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Perry Renshaw
Depression, Depressive Disorder
Evaluation of the Naturalistic User Experience of the Website "ich Bin Alles @Schule" (i Am Everything @school)
The aim of this study is to investigate the naturalistic user experience and acceptance of the German website "ich bin alles @Schule".
- Conditions
- Depression, Depressive Disorder, Depression in Children, Depression in Adolescence
- Trial name
- NCT06668688
- Testing
- "ich bin alles @Schule" (i am everything @school; www.schule.ich-bin-alles.de)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Depression, Depressive Disorder
Web-based Self-help Intervention for Adolescents With Acute or Remitted Major Depressive Disorder
This study aims to evaluate the feasibility and effectiveness of a web-based self-help intervention in adolescents with acute or remitted major depressive disorder.
- Conditions
- Depression, Depressive Disorder, Depressive Symptoms, Depressive Disorder, Major
- Trial name
- NCT04994470
- Testing
- Two-week web-based self-help intervention based on principles of positive psychology, Two-week web-based text messages containing fun facts
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Depression, Subclinical Depressive Symptoms
Cognitive Training Video Game to Target Subclinical Depressive Symptoms in Youth
The purpose of the study is to determine how cognitive control training (CCT) changes behavior in youth with subclinical depressive symptoms.
- Trial name
- NCT05697627
- Testing
- Computerized cognitive training (CCT) using EndeavorRx
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Michigan
Posttraumatic Stress Disorder, Depression
Controlled Trial of Early Intervention With Children and Adolescents Exposed to Nonrelational Traumatic Events
Background: International studies have shown that a substantial number of children and adolescents are exposed to potentially traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT02299583
- Testing
- Preventive intervention trauma-informed early intervention
- Where
- Denmark
- Volunteers
- 684 people
- Sponsor
- Carolina Magdalene Maier