Clinical trials: Adolescent Depression
Depression
Clinical Study of Cang Ai Volatile Oil (CAVO) on Mild to Moderate Depression in Children and Adolescents
A randomized controlled trial was conducted to observe the improvement of mild to moderate depressive symptoms in children and adolescents with the aromatic herbal compound Cang Ai Volatile Oil (CAVO) and to evaluate the…
- Trial name
- NCT05789186
- Testing
- CAVO aromatherapy patch at 3% concentration+Fluoxetine hydrochloride mimetic, Fluoxetine hydrochloride tablet+CAVO aromatherapy patch at 0.1% concentration, Fluoxetine hydrochloride mimetic+CAVO aromatherapy patch at 0.1% concentration
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Chen Qian
Major Depressive Disorder
Efficacy and Safety of Bupropion Hydrobromide in Adolescents and Children With Major Depressive Disorder
Double-Blind, Placebo-Controlled, Multicenter Study of Efficacy and Safety
- Trial name
- NCT02129751
- Testing
- bupropion hydrobromide
- Volunteers
- 246 people
- Sponsor
- Bausch Health Americas, Inc.
Anxiety Disorders, Depressive Disorder
Brief Transdiagnostic Group CBT for Adolescents With Internalizing Problems: A Randomized Waitlist Controlled Trial
The investigators will evaluate a brief group-based cognitive-behavioral treatment program for adolescents aged 13-17 years with internalizing problems.
- Conditions
- Anxiety Disorders, Depressive Disorder, Anxiety, Depression
- Trial name
- NCT04716777
- Testing
- Brief Transdiagnostic group-based Cognitive-Behavioral Treatment
- Where
- Iceland
- Volunteers
- 50 people
- Sponsor
- University of Iceland
Depression, Parent-Child Relations
Parent Encouragement And Coaching of Happiness in Youth
The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response to reward. The main questions it aims to answer are: Aim 1.
- Trial name
- PEACHY (NCT06725160)
- Testing
- Parent Coaching, Active Control
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Concussion, Brain, TBI
Collaborative Care Model for the Treatment of Persistent Symptoms After Concussion Among Youth
SPECIFIC AIMS While post-concussive symptoms following sports-related concussion are typically transient and resolve spontaneously within two weeks of concussive injury, 14% or more of youth who sustain concussion experience…
- Conditions
- Concussion, Brain, TBI, Depression, Anxiety
- Trial name
- NCT03034720
- Testing
- Collaborative Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Seattle Children's Hospital
Depressive Disorder, Major Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR) In The Treatment Of Child and Adolescent Outpatients With Major Depressive Disorder
The primary purpose of this study is to evaluate the long-term safety and tolerability of Desvenlafaxine Succinate Sustained-Release (DVS SR) in child and adolescent outpatients with major depressive disorder.
- Trial name
- NCT00669110
- Testing
- Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR)
- Where
- 9 sites in United States
- Volunteers
- 40 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Depressive Symptom
Digital Cognitive Behavioral Therapy for Chinese Adolescents With Depressive Symptoms（CADS-D )
CADS-D aimes to evaluate the effectiveness and feasibility of a newly DCBT program for Chinese adolescents with depressive symptoms.
- Trial name
- CADS-D (NCT07163013)
- Testing
- Digital cognitive behavioral therapy(DCBT), Regular mental health curriculum
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Adolescent - Emotional Problem, Depression
Randomized, School-based Effectiveness Trial of the Adolescent Depression Awareness Program
The primary goal of the proposed research is to assess the effectiveness of the Adolescent Depression Awareness Program (ADAP), a school-based depression education program, in increasing depression literacy and treatment seeking…
- Conditions
- Adolescent - Emotional Problem, Depression, Prevention Harmful Effects
- Trial name
- ADAP (NCT02099305)
- Testing
- Adolescent Depression Awareness Program (ADAP)
- Where
- 2 sites in United States
- Volunteers
- 17,000 people
- Sponsor
- Johns Hopkins University
Depression
Depression Prevention Initiative - A Study of Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) in School Settings
This study is a randomized controlled trial comparing Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) to group counseling (GC) for the prevention of depression in adolescents.
- Trial name
- NCT01201382
- Testing
- IPT-AST, Group Counseling
- Where
- 2 sites in United States
- Volunteers
- 185 people
- Sponsor
- Children's Hospital of Philadelphia
Anxiety Disorder, Depressive Disorder
Internet Transdiagnostic-CBT for Anxiety and Depression in Adolescents
This study represents the first research program to assess the efficacy of transdiagnostic cognitive behavior therapy (T-CBT) delivered via internet for anxiety and depression in adolescents.
- Conditions
- Anxiety Disorder, Depressive Disorder, Emotional Disorder
- Trial name
- NCT04182061
- Testing
- The AMTE protocol
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad Nacional de Educación a Distancia
Depression
Effects of Aerobic Exercise Intensity on Clinical & Neural Outcomes in Depressed Youth
This study will assess the effects of moderate vs. high intensity aerobic exercise, performed 3 times a week for 12 weeks under supervised conditions, on symptoms of depression, cognitive functioning and brain function in…
- Trial name
- NCT04110041
- Testing
- Aerobic Exercise
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Royal's Institute of Mental Health Research
Major Depression
Discontinuation Study Of Citalopram (Antidepressant) in Depressed Adolescents
The purpose of the study is to evaluate whether it is advantageous for adolescents who have recovered from depression after a 6 to 12 week course of antidepressant treatment to stay on the treatment a further 6 months or is it…
- Trial name
- NCT00249886
- Testing
- Citalopram
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Depression
Cognitive-Behavioral Therapy With Exercise Training in Adolescent Females With Elevated Depression Symptoms
PURPOSE: To Study the Effect of Cognitive-behavioral therapy combined with exercise training in adolescent females with elevated depression symptoms BACKGROUND: Teenagers are more likely than any other age group to experience…
- Trial name
- NCT06281288
- Testing
- Cognitive-Behavioral Therapy, Exercise Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Doaa Tammam Atia
Mood Disorders in Children and Adolescents
Integrated Treatment for Youth With Mood Disorders
In an effort to understand the effects of evidence-based interventions on children and adolescents, the aims of this study are to: 1.
- Trial name
- NCT03800303
- Testing
- Family-based treatment
- Where
- 3 sites in United States
- Volunteers
- 84 people
- Sponsor
- Mayo Clinic
Anxiety Symptoms, Depressive Symptoms
Project COPE-Spain (Coping Options for Parent Empowerment)
The goal of this study trial is to establish the preliminary clinical utility of the COPE program (Coping Options for Parent Empowerment) adapted for caregivers of adolescents in the Spanish context.
- Conditions
- Anxiety Symptoms, Depressive Symptoms, Parental Stress
- Trial name
- COPE-ES (NCT07006220)
- Testing
- COPE Program
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad Nacional de Educación a Distancia
AOD Use, Abuse, and Dependence, Depression
Treatment for Teens With Alcohol Abuse and Depression
The investigators will recruit adolescents with alcohol or cannabis abuse and clinically significant depression. All participants will receive 12 sessions of an evidence-based treatment for alcohol abuse, Motivation Enhancement…
- Trial name
- T-TAAD (NCT02227589)
- Testing
- MET/CBT-12, CBT-D, D-TAU
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- Duke University
Depressive Symptoms, Trauma, Psychological
Improving Mental Health and School Performance in Urban Eighth Graders
This study assesses: (1) the impact of the Relax, Be Aware, Do a Personal Rating (RAP) Club, a school-based prevention program for urban eighth graders, on students' emotional functioning and education outcomes; (2) potential…
- Conditions
- Depressive Symptoms, Trauma, Psychological, Disruptive Behavior
- Trial name
- NCT03906682
- Testing
- RAP Club, Healthy Topics
- Where
- United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health