Clinical trials: Adolescent Depression
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Anxiety, Depression
Attention Bias Modification Training for Young People
Attention bias modification training (ABMT) is a computer-based attention training programme designed to modify the way a person's attention is directed to mild threats in the environment.
- Trial name
- NCT02270671
- Testing
- ABMT
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Involutional Depression, Anxiety Disorders
MRI Study of Brain Activity and Risk for Depression in Adolescents
Anxiety in children of parents with major depressive disorder (MDD) poses a particularly high risk for later-life MDD. In adults, MDD involves dysfunction in prefrontal brain regions that regulate attention to emotional stimuli.
- Trial name
- NCT00047944
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Suicidal Ideation
BRITEPath, Component 3 of iCHART (Integrated Care to Help At-Risk Teens)
BRITEPath (BP) aims to support co-located mental health clinicians in the development of a high quality, effective, and personalized safety plan for referred patients who screen positive for depression and/or suicidal ideation.
- Trial name
- NCT04000399
- Testing
- BRITEPath
- Where
- 6 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Pittsburgh
Depression, Anxiety
Game-Based Digital Intervention for Depression in Adolescents
The goal of this clinical trial is to evaluate the effectiveness of digital interventions in treating depression and anxiety in adolescents.
- Trial name
- NCT06778785
- Testing
- Digital Intervention, Health Education, Personalization Algorithm
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Depression, Eating Disorders
Implementation of Project YES in Ambulatory Adolescent & Young Adult Medicine
This study tests a suite of single-session intervention (SSI) targeting risk factors for depression and eating disorders among adolescents and young adults.
- Conditions
- Depression, Eating Disorders, Anxiety
- Trial name
- NCT06359951
- Testing
- Project YES
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Major Depressive Disorder, Dysthymic Disorder
Cognitive Behavioral Therapy for Early-Onset Depression
Depression is a debilitating illness affecting large numbers of young people. In this study, children and adolescents ages 10 to 17 meeting criteria for clinical depression will participate in a 15-session group therapy…
- Trial name
- NCT00096642
- Testing
- Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Adolescent Depression
Repetitive Transcranial Stimulation (rTMS) for Resistant Depression in Adolescents
The investigators hypothesis that repetitive transcranial Stimulation (rTMS) is a safe and effective add-on therapy for resistent depression in adolescent patients.
- Trial name
- NCT01170520
- Testing
- repetitive transcranial Stimulation
- Where
- 2 sites in Israel
- Volunteers
- 24 people
- Sponsor
- Shalvata Mental Health Center
Depression
Addressing Mental Health in African American Job Training Adolescents and Young Adults
This project's focus is twofold-to change the culture of an employment training program for adolescents and young adults (Youth Opportunities, or "YO") to more fully address the many mental health issues faced by its participants…
- Trial name
- NCT00979524
- Testing
- Comprehensive Mental Health Services and Supports
- Where
- United States
- Volunteers
- 782 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Nursing
Mandala Activity and Adolescents With Cancer
Aim: The aim of this study is to determine the effect of mandala activity on adolescents receiving cancer treatment on psychological symptoms and anxiety/depression level.
- Trial name
- NCT04297982
- Testing
- Mandala Activity, Routine nursing care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Depression, Anxiety
Clinical and Cost Effectiveness of Brief Cognitive-Behavioral Therapy (CBT) for Pediatric Internalizing Disorders
This project assesses the clinical and cost effectiveness of brief cognitive-behavioral therapy (CBT) for depressed (ages 11-17) and anxious (ages 8-17) youths seen for services in pediatric primary care.
- Trial name
- NCT00669526
- Testing
- BCBT, SMHC referral
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Robert Wood Johnson Foundation
Depression, Anhedonia
Imagine a Brighter Future: An Intervention to Improve Positive Emotions in Young People
Depression is a common mental health problem that often begins during adolescence. Onset during adolescence can be disruptive to schoolwork and social relationships and if left untreated can lead to recurrence during adulthood…
- Trial name
- IMAGINE-P (NCT05507385)
- Testing
- IMAGINE-POSITIVE, Control
- Where
- United Kingdom
- Sponsor
- King's College London
Sleep, Depression
Behavioral and Sleep Hygiene Education With Mindfulness Intervention to Improve Sleep Regularity in Adolescents
Sleep plays a fundamental role in both mental- and physical-health, with good sleep health including adequate duration and quality, appropriate timing, regularity, and absence of sleep disorders.
- Conditions
- Sleep, Depression, Anxiety, Chronotype
- Trial name
- NCT06028997
- Testing
- Behavioral and Sleep Hygiene Education with Mindfulness Intervention
- Where
- 2 sites in Iceland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Solveig Magnusdottir
Anhedonia, Depression and Suicide Ideation
Get ActivE Study for At-risk Youth
The study will adapt and deploy a digital Behavioral Activation app with mobile sensing, supported by health coaches, that encourages youth to engage in positive activities.
- Trial name
- GetActivE (NCT06829953)
- Testing
- GET ActivE, Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Pittsburgh
Depressive Disorder, Major
Aerobic Group Exercise for Adolescents With Depression
The aim is to evaluate aerobic group exercise versus leisure group activities in adolescents with mild to moderate depression. Primary outcome is Children's Depression Rating Scale - Revised (CDRS-R).
- Trial name
- NCT04695145
- Testing
- Aerobic exercise in group, Group sessions with leisure activities
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Lund University Hospital
Depressive Disorder, Anxiety Disorders
Research of Unified Protocol for the Treatment of Common Mental Disorders in Adolescents in Hong Kong
The Unified Protocol (UP) is an emotion-focused, cognitive-behavioural intervention that is developed to target core temperamental characteristics underlying anxiety and depressive disorders.
- Trial name
- NCT04091139
- Testing
- Unified protocol for adolescents (UP-A), Treatment as usual (TAU)
- Where
- Hong Kong
- Volunteers
- 27 people
- Sponsor
- Chinese University of Hong Kong
Postpartum Depression
Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers
The Specific Aim of this study is to conduct a randomized controlled trial to evaluate whether Project REACH (an interpersonal psychotherapy-based intervention) compared with a didactic attention-control program reduces the risk…
- Trial name
- REACH 2 (NCT01482832)
- Testing
- Interpersonal therapy-based treatment
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Depression, Unipolar, Eveningness
Effects of CBT and BLT in Youth With Unipolar Depression and Evening Chronotype
The goal of this prospective randomised controlled trial is to examine the effects of cognitive behavioural therapy and bright light therapy in youths with unipolar depression and evening chronotype.
- Trial name
- DELAY (NCT06092411)
- Testing
- Cognitive Behavioural Therapy for Depression, Bright Light Therapy
- Where
- Hong Kong
- Volunteers
- 162 people
- Sponsor
- The University of Hong Kong
Tourette Syndrome in Adolescence, Social Adjustment
Board Game Project for Adolescents with Tourette Syndrome
The study aims to investigate the effectiveness of using a board game to improve adolescents' tics, mental health, and interpersonal interactions.
- Conditions
- Tourette Syndrome in Adolescence, Social Adjustment, Psychosocial Functioning
- Trial name
- NCT05566236
- Testing
- board game
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Depressive Disorder, Anxiety Disorders
Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression
Psychological therapies for depression have demonstrated efficacy, but outcomes are still unsatisfactory, especially in cases with high comorbidity.
- Trial name
- NCT01829100
- Testing
- Group Behavioral Activation Therapy (GBAT)
- Where
- United States
- Volunteers
- 895 people, healthy volunteers welcome
- Sponsor
- Rutgers University