Clinical trials: Adolescent Obesity
Obesity, Adolescent
Myokines Role During Obesity
We showed, for the first time, that Z-score increase during obesity was dependent on sex, severity of obesity and age but also on the bone site.
- Trial name
- Bonamy (NCT02973867)
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Pediatric Obesity
Exercise Intensity and Appetite in Adolescents
Acute exercise has been shown to affect subsequent energy intake in obese adolescents. Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the individual maximal capacities) can reduce energy…
- Trial name
- NCT02484612
- Testing
- acute exercise
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université Blaise Pascal, Clermont-Ferrand
Physical Activity, Sedentary Behaviors
School Intervention Program to Promote Healthy Lifestyle Among Male Adolescent Students in King Faisal Residential City, Jeddah, Western Region, 2014-15
Through a cluster randomized control trial, 148 male adolescents' students were randomly assigned into either intervention group who received an educational program for two months (n=79), or control groups (n=69) who didn't…
- Conditions
- Physical Activity, Sedentary Behaviors, Dietary Habits, Obesity
- Trial name
- NCT03885700
- Testing
- Educational program for 2 months
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- King Abdullah International Medical Research Center
Obesity
Sleep Timing and Insulin Resistance in Adolescents With Obesity
This study examines the relationship between sleep timing and insulin resistance in adolescents with obesity. The investigators also aim to develop a physiologically-based mathematical model of adolescent sleep/wake and circadian…
- Trial name
- NCT02585830
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity, Weight Gain
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
The goal of the study is to assess how tirzepatide impacts bodyweight and cardiovascular risk factors when used in conjunction with healthy nutrition and physical activity in adolescents with obesity and multiple weight related…
- Trial name
- NCT06439277
- Testing
- Tirzepatide
- Where
- 69 sites in United States, Argentina and 10 more
- Volunteers
- 300 people
- Sponsor
- Eli Lilly and Company
Obesity, Diabetes
Preventing Diabetes in Latino Youth
Obesity and type 2 diabetes are critical public health issues in youth. This study will test the effects and estimate the cost-effectiveness of a culturally-grounded community-based lifestyle intervention on type 2 diabetes risk…
- Trial name
- NCT02615353
- Testing
- Intensive Lifestyle Intervention, Usual Care Control
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Arizona State University
Insulin Resistance, Obesity
The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity, Preference and Brain Response in Adolescents
The purpose of this study is to investigate the effects of dietary exposure to artificial sweeteners on taste sensitivity, preference and brain response in adolescents using fMRI, psychophysical measures, and questionnaires.
- Trial name
- NCT02499705
- Testing
- Sucralose, Sucrose, Sucralose + maltodextrin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity, Morbid
4XL Study - Obesity Surgery in Adolescence
The purpose of this study on adolescents between 13 and 18 years of age with morbid obesity is to determine whether surgical treatment gives more health benefits than standard conservative treatment, and if laparoscopic gastric…
- Trial name
- 4XL (NCT00923819)
- Testing
- Laparoscopic gastric bypass, Standard conservative treatment
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset i Vestfold HF
Non-Alcoholic Fatty Liver Disease, Childhood Obesity
Clinical Epidemiology of NAFLD in Children and Adolescents
Background: Non-alcoholic fatty liver disease (NAFLD) is rapidly increasing alongside overweight and obesity, not only in adults but also in children and adolescents.
- Trial name
- LiverKids (NCT05526274)
- Testing
- Vibration-Controlled Transient Elastography (VCTE) with Controlled Attenuation Parameter (CAP)
- Where
- Spain
- Volunteers
- 2,866 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Vitamin D Deficiency, Obesity
Vitamin D Deficiency in Obese Adolescent Girls and Influence of Vitamin D on Insulin Secretion and Sensitivity
Sub-clinical vitamin D deficiency is a commonly unrecognized disorder in obese adolescents. The investigators hypothesize vitamin D deficiency will be highly prevalent in obese adolescents and those who are vitamin D deficient…
- Conditions
- Vitamin D Deficiency, Obesity, Insulin Resistance
- Trial name
- NCT00850694
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- University of Alabama at Birmingham
Hypertension in Adolescence, Adolescent Overweight
Hypertension in High School Students
Hypertension and obesity in the young population are major risk factors for renal and cardiovascular events, which could arise in adulthood.
- Trial name
- HYGEF (NCT06049641)
- Where
- Italy
- Volunteers
- 2,638 people, healthy volunteers welcome
- Sponsor
- Ospedale San Raffaele
Overweight and Obesity
Investigation of Peak Expiratory Flow and Physically Fitness in Obese and Overweight Adolescents
Due to the increasing prevalence of childhood obesity and overweight, health problems may begin to appear at an early age. The aim of this study is to examine physical activity level, core performance, anthropometric measurements…
- Trial name
- NCT05470556
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biruni University
Obesity, Childhood
Group Telehealth Weight Management Visits for Adolescents With Obesity
Summary Description The goal of this intervention study is to test how well does a weight management curriculum work in virtual group-based medical visits (telehealth) for the treatment of adolescents with obesity.
- Trial name
- NCT03508622
- Testing
- Telehealth group sessions, Empower clinic
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Children's Hospital Los Angeles
Obesity, Status Post Sleeve Gastrectomy
Liraglutide (Saxenda(R)) in Adolescents With Obesity After Sleeve Gastrectomy
Background: Metabolic Bariatric Surgery, including a surgery called vertical sleeve gastrectomy, is the most effective weight loss treatment for severe obesity.
- Trial name
- NCT04883346
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Obese Adolescents
Comparison Between Gastric Band, Laparoscopic Sleeve Gastrectomy, Gastric Bypass Surgeries
Determine the short and long term safety and efficacy of the Gastric bypass , laparoscopic sleeve gastrectomy, and Gastric banding (LAGB) on severely obese adolescents.
- Trial name
- NCT02004561
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Pediatric Obesity, Sleep Apnea, Obstructive
Exercise and Venous Compression on Upper Airway Resistance in Obese Teenagers With OSA
The purpose of this study is to assess the effects of physical exercise, associated or not with venous compression of the leg, on obstructive sleep apnea (OSA) severity and upper airway resistance in obese teenagers.
- Trial name
- OBESOMAC (NCT02588469)
- Testing
- Interventional group, Control group
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Childhood Obesity
Translational Investigation of Growth and Everyday Routines in Kids
The purpose of this study is to determine the effect of severe obesity on physical activity, sedentary behavior and cardiometabolic risk factors during childhood and adolescence and whether these associations are modified by…
- Trial name
- TIGER Kids (NCT02784509)
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Sedentary Lifestyle, Metabolic Disturbance
Sedentary Behavior and Health Outcomes Study
This study is a randomized crossover trial to compare the effectiveness of interrupting SB on glucose homeostasis in the lab and free-living settings.
- Conditions
- Sedentary Lifestyle, Metabolic Disturbance, Pediatric Obesity, Physical Activity
- Trial name
- SBHO (NCT03153930)
- Testing
- Walking breaks, Sitting only
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity, Adolescent, Pre Diabetes
Effect of NNS on Metformin/GDF15, Pilot
Metformin use for diabetes has the benefit of causing weight loss in some. The investigators in a preclinical trial, demonstrated that mice consuming non-nutritive sweetened (NNS) drinks had worse glucose improvements and weight…
- Trial name
- NCT05400863
- Testing
- avoid sugary and NNS drinks plus start Metformin, avoid sugary drinks (allowed water and drinks sweetened with NNS) plus start Metformin
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Morbid Obesity
Bariatric Surgery Outcomes
The UCLA Metabolic and Bariatric Surgery Program (adult program) and the UCLA Fit for Healthy Weight Program (adolescent program) are committed to the care of morbidly obese patients. This study is observational.
- Trial name
- NCT01057784
- Testing
- Bariatric surgery.
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles