Clinical trials: Adolescent Substance Use, open to volunteers
Substance Use, Adolescent Behavior
Parent SMART (Substance Misuse in Adolescents in Residential Treatment)
Adolescents in residential substance use treatment have serious substance-related problems and poor outcomes following discharge: follow-up studies indicate that 60% of adolescents treated in residential treatment will relapse…
- Trial name
- NCT05169385
- Testing
- Parent SMART, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 220 people
- Sponsor
- Brown University
Adolescent Drinking, Adolescent Substance Use
Optimizing and Advancing SBIRT in Schools
The goal of this clinical trial is to establish whether brief interventions for alcohol use can be delivered in schools for both indicated prevention and selected prevention, determine if an expanded workforce is an effective…
- Conditions
- Adolescent Drinking, Adolescent Substance Use, Risk Behavior, Health
- Trial name
- OASIS (NCT06206161)
- Testing
- Indicated Prevention, Clinical Staff, Selective Prevention, Expanded Paraprofessional Workforce
- Where
- United States
- Volunteers
- 21,000 people
- Sponsor
- Massachusetts General Hospital
Opioid-use Disorder, Opioid Dependence
Young Houston Emergency Opioid Engagement System
The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral…
- Conditions
- Opioid-use Disorder, Opioid Dependence, Opioid Overdose, Opioid Use
- Trial name
- YHEROES (NCT04811014)
- Testing
- Buprenorphine, Naloxone Drug Combination, Individual Counseling, Peer Recovery Support Services
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Use Behavior, Nicotine Dependence Tobacco Product
§SMOKE Nicotine and Tobacco Youth Cohort
The §SMOKE Cohort Study aims to improve understanding of tobacco and nicotine use among adolescents and young adults in Denmark.
- Conditions
- Tobacco Use Behavior, Nicotine Dependence Tobacco Product, E-Cigarette Use, Smoking ( Cigarette)
- Trial name
- NCT07910331
- Where
- Denmark
- Volunteers
- 10,000 people
- Sponsor
- University of Southern Denmark
Substance Use (Drugs, Alcohol), Tobacco Use
The ICEC Cluster Trial: Integrated Community Engagement Collaborative for Youth Substance Use Prevention in Rural America
This study will evaluate whether the Integrated Community Engagement (ICE) Collaborative can help prevent alcohol, tobacco, and other drug use among youth living in rural communities.
- Conditions
- Substance Use (Drugs, Alcohol), Tobacco Use, Adolescent Substance Use
- Trial name
- NCT07843576
- Testing
- Integrated Community Engagement Collaborative, School-Based Data Collection and Reporting without Network Coordinator Support
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Behavioral Health
Testing the Effectiveness and Implementation of a Meditation App for Youth in the Legal System
The goals of this hybrid type 2 randomized controlled trial (RCT) are to evaluate the effectiveness and individual-level implementation of a 1-month app-based meditation program with youth on probation in Cook County, IL.
- Trial name
- NCT06997120
- Testing
- Bodhi AIM (intervention group), HIB (control group)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Alcohol Problem
Game-Based Intervention to Reduce Alcohol Use Among Youth
This is a randomized controlled trial to learn if the Singularities, a game-based intervention, works to reduce alcohol-related harms among youth.
- Trial name
- NCT07463118
- Testing
- Food4Thought, Singularities
- Where
- United States
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Substance Use Disorders (SUDs)
Recovery Opportunities Through Ongoing Treatment Sustainment
Adolescents in rural communities face limited access to effective substance use services, increasing their risk for opioid and other substance use disorders.
- Trial name
- ROOTS (NCT07746401)
- Testing
- Youth Substance Use Unit
- Volunteers
- 60 people
- Sponsor
- University of Maryland, College Park
Opioid Use Disorder, Pain, Chronic
Adolescent Outcomes of Post-operative Opioid EXposure
The goal of this observational study is to examine the factors associated with the transition from medical exposure to opioids with "signposts" of future opioid use disorder among adolescent surgical patients.
- Trial name
- APEX (NCT06350409)
- Where
- 5 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- Sharon Levy
Institutionalization
Life Skills-Based Intervention on Substance Use Intention in Adolescents in Social Care Institutions
Objective: evaluate the impact of a Life Skills Training (LST) intervention on substance use intention by analyzing changes in neuropsychological organization and psychological regulation processes in adolescents living in social…
- Trial name
- CASA-HpV (NCT07492069)
- Testing
- Life Skills Training (LST), Psicoeducation Traditional
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Vaping, E Cig Use
A Hybrid Program to Prevent Substance Use Risk Among Upper Elementary School Students Using a Positive Youth Development Approach
The goal of this randomized controlled trial is to evaluate a psychosocial school-based hybrid intervention which includes traditional classroom sessions and online e-learning modules to reduce risk of vaping and prescription…
- Conditions
- Vaping, E Cig Use, Prescription Drug Misuse
- Trial name
- NCT07162155
- Testing
- School-based Hybrid Intervention to Prevent Vaping and Prescription Drug Misuse
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Christopher Williams
Behavior, Health
Train Your Brain 2.0 - Improving Memory and Decision Making Among Youth
The goal of this clinical trial is to deliver a computer-based working memory training program to improve delay discounting (DD) and prevent substance misuse among at-risk adolescents in a traditionally underserved area.
- Trial name
- NCT06242704
- Testing
- Working Memory Training, Working Memory
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wayne State University
E-cigarette Use, Cigarette Smoking Risk
An Online Intervention to Reduce E-cigarette Use and Cigarette Smoking Risk in Adolescents
The goal of this clinical trial is to learn if a brief digital intervention can reduce e-cigarette use and prevent cigarette smoking initiation in teenagers ages 12-17.
- Trial name
- NCT07624292
- Testing
- Virtual Intervention for Behavioral Empowerment (VIBE)
- Volunteers
- 150 people
- Sponsor
- University of Southern California
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Mental Health Issue, Substance Use Disorders
Comparing the Effect of Adding a Remote Self-reporting Tool for Distress and Fit-for-purpose Mental Health & Addictions Service to Usual Case Management on Dropout Rates in a Vocational Training Program
Youth unemployment is a chronic problem in most societies. Some young adults are neither in employment, education or training (NEET), and are at high risk of chronic unemployment, social disengagement and poor quality of life.
- Conditions
- Mental Health Issue, Substance Use Disorders, Distress, Emotional
- Trial name
- TeachMeToBuild (NCT05626374)
- Testing
- Basic Case Management, Basic Case Management plus Distress Tool, Basic Case Management plus rapid mental health & addictions healthcare access
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Royal Victoria Hospital, Canada
Adverse Childhood Experiences, Family Functioning
The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
The goal of this 2-arm randomized control trial is to determine the impact of a community health worker delivered coaching intervention, GRIT, on preventing the early initiation of regular use of alcohol and cannabis among…
- Trial name
- NCT06821035
- Testing
- Garnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC)
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Depression - Major Depressive Disorder, Bipolar
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health (BLOOM) is a project that aims to overcome age and diagnostic boundaries to generate person-specific longitudinal profiles of mental…
- Conditions
- Depression - Major Depressive Disorder, Bipolar, Psychosis, Eating Disorder NOS
- Trial name
- BLOOM (NCT06978452)
- Where
- Canada
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
E-cigarette Use, Substance Use
The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth
The purpose of this research proposal is to develop and evaluate a culturally grounded, ENDS prevention intervention for rural Hawaiian youth. This will be accomplished through two specific aims.
- Trial name
- NCT06929520
- Testing
- ENDS Prevention Intervention (TBD)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Adolescent Development
Monetary Incentive Delay Task for Probing Reward-related Neural Processes
150 males and 150 females ages 14-17 years-old will be enrolled in an observational, longitudinal study. There are three planned in-person visits: a baseline assessment, an 18-month follow-up, and a 36-month follow-up.
- Trial name
- MID (NCT06369623)
- Testing
- Monetary Incentive Delay Task
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Vaping, Vaping Teens
Behavioral Intervention for Youth to Promote Vaping Cessation
This study will test the hypothesis that the QuitVaping (QV) intervention and additional texting support will improve nicotine abstinence rates in adolescents as compared to Enhanced Usual Care (EUC: education about nicotine…
- Conditions
- Vaping, Vaping Teens, Nicotine Dependence
- Trial name
- VIA (NCT06765291)
- Testing
- QuitVaping, This is Quitting (TIQ)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital