Clinical trials: Adolescent Suicide
Suicide, Attempted, Suicide, Ideation
Teen Brain Training (TBT)
A non invasive treatment study including participants at risk for suicide attempts and undergoing neurofeedback training. Neurofeedback is controlling your brain activity in real time inside the scanner.
- Conditions
- Suicide, Attempted, Suicide, Ideation, Depression
- Trial name
- NCT06183580
- Testing
- neurofeedback training involving dACC, neurofeedback training involving amygdala
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Suicide, Attempted, Suicidal Ideation
Mobile Technology for Reducing and Preventing Adolescent Suicide
This single-group open-label trial will evaluate the feasibility and preliminary efficacy of a suicide prevention mobile application when used as an adjunct to usual care in adolescents.
- Trial name
- NCT04896593
- Testing
- Smartphone App
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Hartford Hospital
Depression, Suicidal Ideation
BRITEPath, Component 3 of iCHART (Integrated Care to Help At-Risk Teens)
BRITEPath (BP) aims to support co-located mental health clinicians in the development of a high quality, effective, and personalized safety plan for referred patients who screen positive for depression and/or suicidal ideation.
- Trial name
- NCT04000399
- Testing
- BRITEPath
- Where
- 6 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Pittsburgh
Depression, Suicidal Ideation
Screening Wizard, Component 1 of iCHART (Integrated Care to Help At-Risk Teens)-Feasibility/Pilot Phase
Screening Wizard (SW). Primary Care Providers (PCPs) are often uncertain about how to best refer adolescents who screen positive for depression or suicidality.
- Trial name
- NCT03985813
- Testing
- Screening Wizard
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- University of Pittsburgh
Depression, Suicidal Ideation
Text2Connect, Component 2 of iCHART (Integrated Care to Help At-Risk Teens)
This study proposes to develop and examine a personalized, text-based intervention designed to improve engagement with mental health (MH) treatment.
- Trial name
- T2C (NCT03982043)
- Testing
- Text2Connect
- Where
- 4 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Pittsburgh
Covid19, Mental Health
Mental Health Among Patients, Providers, and Staff During the COVID-19 Era
The Mental Health Among Patients, Providers, and Staff (MHAPPS) Study is designed to study how the COVID-19 pandemic has affected mental health and wellbeing, and how to support mental health while minimizing the burden on the…
- Trial name
- MHAPPS (NCT04700137)
- Testing
- Caring Contacts Plus Introductory Phone Call (CC+), Caring Contacts without an introductory phone call (CC)
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Suicide
Promoting Community Conversations About Research to End Native Youth Suicide in Rural Alaska
This intervention study measures the outcomes of the PC CARES (Promoting Community Conversations about Research to End Suicide) project implemented in remote rural Alaskan villages.
- Trial name
- PC CARES (NCT03661255)
- Testing
- PC CARES
- Where
- United States
- Volunteers
- 1,427 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Suicidal Ideation
Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents
To address the unmet need of optimizing the treatment and management for adolescent suicidality, the investigators propose to evaluate the effectiveness and safety of telehealth services compared to inpatient and OCIC for…
- Trial name
- Pre-START (NCT04625686)
- Testing
- Mental Health Treatment
- Where
- 4 sites in United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Suicide, Attempted, Suicide and Depression
Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents
This project aims to examine the signal of efficacy of ketamine, a rapidly acting medication shown to decrease suicidality in adults in as short as hours or days, as opposed to weeks.
- Conditions
- Suicide, Attempted, Suicide and Depression, Suicide Threat
- Trial name
- TASK (NCT04592809)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicidal Ideation, Suicide, Attempted
Skills to Enhance Positive Affect in Suicidal Adolescents
The prevalence of suicidal behaviors in adolescents remains unacceptably high and is a significant public health concern. The investigators propose a new treatment approach in which skills to increase positive emotions are taught…
- Trial name
- STEP (NCT02130583)
- Testing
- Positive Affect Skills Training, Treatment as Usual
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Brown University
Adolescent Suicide, Adolescent Depression
Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine
The purpose of this study is to determine if intravenous ketamine reduces suicidal thinking compared to an active placebo (midazolam) in adolescents who have treatment resistant depression and a recent history of a suicide event…
- Trial name
- NCT04613453
- Testing
- Ketamine Infusion, Midazolam Infusion
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Yale University
Major Depressive Disorder, Major Depressive Episode
Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder
The primary goal of the proposed study is to compare the effectiveness of universal school based screening for adolescent major depressive disorder to the current school process of targeted screening based on concerning behavior.
- Trial name
- NCT03716869
- Testing
- Universal Screening Arm
- Where
- United States
- Volunteers
- 12,909 people
- Sponsor
- Milton S. Hershey Medical Center
Substance Misuse, Suicide
A Digital Game Targeting Suicide Prevention in Adolescents Who Report Substance Misuse
The primary aim of this study is to design and develop a digital game that models the process of a safety planning intervention.
- Trial name
- NCT05517382
- Testing
- supportED, Control
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Yale University
Suicide
Coping Long Term With Attempted Suicide - Adolescents
This study is to develop an adjunctive intervention for acutely suicidal adolescents who have been admitted to a psychiatric inpatient unit.
- Trial name
- CLASP-A (NCT01748760)
- Testing
- CLASP-A intervention, Treatment as Usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brown University
Bipolar Disorder, Major Depressive Disorder
Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms
The purpose of this study is to advance a non-pharmacologic suicide preventive intervention with wide dissemination potential as an innovative high-yield solution to reduce suicide rates.
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Mood Disorders, Suicide
- Trial name
- NCT05317481
- Testing
- BE-SMART-DR, psychoeducational control comparator condition (CC)
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Yale University
Suicide, Engagement, Patient
The BH-Works Suicide Prevention Program for Sexual and Gender Minority Youth
Youth suicide is a serious public health concern. Compared to their heterosexual and cisgender peers, sexual and gender minority (SGM) adolescents report higher rates of suicidal ideation and suicide attempts.
- Trial name
- NCT05922670
- Testing
- The Behavioral Health-Works Suicide Prevention Program for Sexual and Gender Minority Youth
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- Virginia Polytechnic Institute and State University
Self-Harm, Depression
Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
To measure NAC-induced changes to concentrations of glutathione (GSH) in the anterior cingulate cortex (ACC) as measured by magnetic resonance spectroscopy (MRS) in 36 adolescents and young adults with NSSI (12 in each group…
- Conditions
- Self-Harm, Depression, Suicide
- Trial name
- NCT04005053
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Suicidal Ideation, Suicide, Attempted
Safety Planning in Juvenile Justice for Suicidal Youth
This study will examine the feasibility and acceptability of a program designed to conduct safety planning with youth in the juvenile justice system who are at risk for a suicide attempt and/or self-injury and to increase the…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self-injury
- Trial name
- Safety (NCT03655470)
- Testing
- Safety Planning, Standard care
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Brown University
Nonsuicidal Self Injury, Self Hatred
Single-Session Intervention Targeting Self-Injurious Behavior in Adolescents
Participants (aged 13-16) will be randomized to: (1) an online, active control group program encouraging feelings disclosure (i.e.
- Conditions
- Nonsuicidal Self Injury, Self Hatred, Suicidal Thoughts, Suicide Attempts
- Trial name
- Project SAVE (NCT04498143)
- Testing
- Project SAVE ("Stop Adolescent Violence Everywhere") SSI, Active Comparator: Supportive Therapy ("Share Your Feelings") SSI
- Where
- United States
- Volunteers
- 565 people, healthy volunteers welcome
- Sponsor
- University of Denver