Clinical trials: Adult ICU Patients
Gastric Emptying, Enteral Nutrition (Food for Special Medical Purposes)
Cold vs Warm Enteral Feeding and Gastric Emptying in Adult ICU Patients
In critically ill patients receiving enteral nutrition in the intensive care unit, the functional capacity of the gastrointestinal system can be significantly influenced by the mode of nutritional support.
- Trial name
- NCT07415616
- Testing
- enteral nutrition
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Burns, Pain
Music Therapy and Pain Management in Burn Patients.
This is a randomized clinical trial studying the effectiveness of music therapy (i.e. MAR - Music-Assisted Relaxation) on pain intensity in burn patients hospitalized at the Adults Intensive Care Unit of the University Hospital…
- Trial name
- NCT04571255
- Testing
- Music-Assisted Relaxation
- Where
- Colombia
- Volunteers
- 82 people
- Sponsor
- Fundación Santa Fe de Bogota
Pneumonia
Study to Demonstrate the Clinical Efficacy of Levofloxacin in the Treatment of Pneumonia
Primary Objective: The primary objective of the study is to demonstrate the non-inferiority in clinical efficacy at the test of cure (TOC) visit planned 5-7 days after treatment completion of levofloxacin 750 mg once daily (od)…
- Trial name
- NCT00253955
- Testing
- Levofloxacin, Piperacillin/Tazobactam
- Where
- 17 sites in Austria, Belgium and 15 more
- Volunteers
- 460 people
- Sponsor
- Sanofi
Respiratory Distress Syndrome, Adult
STUDY OF ELECTRICAL STIMULATION IN PULMONARY FUNCTION IN INTENSIVE CARE UNIT
Introduction: The Mechanical Ventilation (MV), a support method used in Intensive Care Units (ICU), reaches approximately 90% of critical patients whose withdrawal process represents 40% of the total time of their use.
- Trial name
- NCT03712215
- Testing
- Rehabilitation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Metodista de Piracicaba
Red Blood Cell Transfusions, Sex Differences
Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes
Red blood cell (RBC) transfusions are selected based upon matching donor and recipient blood group: donor and recipient sex are not considered when selecting blood for transfusion.
- Conditions
- Red Blood Cell Transfusions, Sex Differences, Health Services, Critically Ill Intensive Care Unit Patients
- Trial name
- SexMATTERS RCT (NCT06840756)
- Testing
- Sex-mismatched red blood cell transfusions, Sex-matched red blood cell transfusions
- Where
- 8 sites in Canada
- Volunteers
- 11,082 people
- Sponsor
- Michelle Zeller
Acute Kidney Injury
Renal Angina Index for Predicting Acute Kidney Injury in Adult ICU Patients
Acute kidney injury (AKI) is a frequent complication of critical illness and is associated with increased morbidity and mortality.
- Trial name
- NCT07863505
- Testing
- Renal Angina Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Izmir Katip Celebi University
Mechanical Ventilation Complication, Ventilator Induced Lung Injury
Mechanical Power and Mortality in Mechanically Ventilated Adults
This prospective observational cohort study aims to investigate the relationship between mechanical power during the first 72 hours of invasive mechanical ventilation and 28-day mortality in mechanically ventilated adult patients…
- Conditions
- Mechanical Ventilation Complication, Ventilator Induced Lung Injury, ARDS, ICU Mortality (Survival Rate)
- Trial name
- NCT07836153
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Zagazig University
Adult, Acute Respiratory Failure Admitted in ICU
Early Non Invasive Ventilation in Immuno-compromized Patients With Acute Respiratory Failure.
Assess the superiority of early non invasive ventilation in comparison to Oxygen therapy only, for immuno-compromized patients with acute respiratory failure
- Conditions
- Adult, Acute Respiratory Failure Admitted in ICU, Immuno Compromized
- Trial name
- IVNICTUS (NCT01915719)
- Testing
- Early non invasive ventilation, Oxygen therapy only
- Where
- France
- Volunteers
- 374 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
All Adult Patients Admitted to theHMPIT ICU for Management of Head Trauma
Quality of Life in Traumatic Brain Injury Patients
The aim of this study is to describe the quality of life of CT patients in our study, at least 6 months after the occurrence of the trauma. This assessment is related to the patient's degree of sequelae, using the GOSE scale.
- Trial name
- NCT05993312
- Testing
- quality of life
- Where
- 2 sites in Tunisia
- Volunteers
- 100 people
- Sponsor
- General Administration of Military Health, Tunisia
Adult ICU Patients
Metabolic Trajectories and Protein Intake in Long-Stay Ventilated Intensive Care Unit (ICU) Patients
Survival of critically ill patients has improved, resulting in a growing population of chronically critically ill (CCI) individuals with prolonged organ dysfunction, mechanical ventilation, and high morbidity.
- Trial name
- MetaChronic (NCT07268274)
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Universidade do Algarve
Age:18-70 Years, Acute Severe Disease
Metabolomics Dynamics Study for Severe Patient
Acute severe disease is a major public health challenge that often affects young adults.In past decade, there are lot of new techniques have been developed that aim to improve the outcome of acute severe disease, But few of these…
- Conditions
- Age:18-70 Years, Acute Severe Disease, Acute Physiology And Chronic Health Evaluation(APACHE)II>10
- Trial name
- NCT02164786
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sichuan Academy of Medical Sciences
Oncologic Complications and Emergencies, Cancer
Validation of Modified Early Warning Score (MEWS) in Predicting Outcomes in Clinical Oncology Ward Adult Patients
This study is to validate the use of the modified early warning score (MEWS) in an adult oncology ward as a predictor of 7 day mortality or intensive care unit (ICU) admission.
- Conditions
- Oncologic Complications and Emergencies, Cancer, Emergencies
- Trial name
- MEWS (NCT02336828)
- Where
- China
- Volunteers
- 171 people
- Sponsor
- Chinese University of Hong Kong
Solid Tumor, Adult
Impact of ICU on the Quality of Life in Cancer Patients
This is an observational, prospective, monocentric, case-control study. Investigators aim to compare the quality of life and oncological treatment strategy in cancer patients admitted or not in ICU.
- Trial name
- QdV-ONCOREA (NCT04310033)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Infectious Diseases
Safety and Efficacy Study of High Dose Colistin
Colistin is a rapidly acting bactericidal antimicrobial agent that possesses a post antibiotic effect against MDRO Gram-negative bacteria, such as as Pseudomonas aeruginosa, Acinetobacterbaumannii, and Klebsiella pneumonia.
- Trial name
- NCT02162966
- Testing
- High Dose Colistin, Standard Dose Colistin
- Where
- Saudi Arabia
- Volunteers
- 330 people
- Sponsor
- King Saud Medical City
Respiratory Failure, Critical Illness
The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial
This clinical trial aims to assess the efficacy of sedation protocol targeting optimal respiratory drive using P0.1 and arousal level compared with conventional sedation strategy (targeting arousal level alone) in patients…
- Conditions
- Respiratory Failure, Critical Illness, Respiratory Distress Syndrome, Adult, Lung Injury
- Trial name
- NCT06203405
- Testing
- Titrating sedation targeting both optimal P0.1 and appropriate arousal level, Fentanyl, Midazolam
- Where
- Thailand
- Volunteers
- 214 people
- Sponsor
- Siriraj Hospital
Blood Glucose
Clinical Study of the Intravenous Blood Glucose System in Hospitalized Adult Elective or Non-Emergent Surgery and Medical/Surgical Intensive Care Unit Patients
The primary objective of this study is to evaluate the performance and safety of the intravenous blood glucose (IVBG) System relative to point of care (POC) meter performance when each method is compared to the Yellow Springs…
- Trial name
- NCT00906490
- Testing
- Intravenous Blood Glucose monitoring system
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- Edwards Lifesciences
Intensive Care (ICU)
An Investigation of The Relationship Between Muscle Mass, Physiological Parameters, and Blood Gas Levels in Adult Patients Hospitalized in The Intensive Care Unit
This study was designed to investigate the relationship between muscle mass and physiological parameters and blood gas values in adult patients admitted to the intensive care unit.
- Trial name
- NCT07866625
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Anemia
SHIIFT: Small Tubes to Halt Medical ICU/IMU Frequent Transfusions
The purpose of this study is to evaluate the effectiveness of small phlebotomy tubes to reduce RBC transfusions in medical intensive care unit (ICU) and Intermediate care unit (IMU) patients with low hemoglobin compared with…
- Trial name
- NCT05750654
- Testing
- Small Phlebotomy Tube Group, Standard Phlebotomy Tube Group
- Where
- United States
- Volunteers
- 688 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain
Pain Management of Intensive Care Unit Patients
The purpose of this study is to evaluate the effect of an algorithm, where ICU patients pain are assessed systematically with valid pain assessment tools and where pain is treated after pain intensity score.
- Trial name
- NCT01599663
- Testing
- Pain management algorithm
- Where
- Norway
- Volunteers
- 650 people
- Sponsor
- Ostfold Hospital Trust
Sepsis - to Reduce Mortality in the Intensive Care Unit, Burns Involving 20% or More of Body Surface
Evaluating the Accuracy of Multiple Blood Tests to Diagnose Sepsis in Adult Burn Patients
This prospective diagnostic accuracy study evaluates the performance of presepsin and C-reactive protein (CRP) as early biomarkers for suspected sepsis in adult burn patients.
- Trial name
- BioBurnSepsis (NCT07126574)
- Where
- South Korea
- Volunteers
- 165 people
- Sponsor
- Dohern Kym