Clinical trials: Adult Periodontitis
Chronic Periodontitis
Effect of Probiotic Inersan and Doxycycline in Chronic Periodontitis
Periodontitis is a multifactorial disease that can lead to the destruction of supporting tissues of the teeth resulting in pocket formation, recession or both.
- Trial name
- NCT02174757
- Testing
- Inersan, Doxycycline
- Where
- India
- Volunteers
- 30 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Periodontitis
Regular Home Use of Dual-light Photodynamic Therapy in the Management of Chronic Periodontitis
The study is a single site, randomized clinical trial designed to determine the efficacy of the Lumoral treatment in periodontitis patients.
- Trial name
- HOPE-CP (NCT05278416)
- Testing
- Lumoral treatment -device and Lumorinse tablets
- Where
- Finland
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Koite Health Oy
Periodontal Pocket, Periodontitis
Multicenter Study on the Use of a Collagen-based Hydrogel for the Treatment of 153 Periodontal Pockets in 38 Adults With Generalized Stage III Periodontitis
This is a prospective, observational, multicenter study designed to evaluate the real-world efficacy and safety of H42®, a collagen hydrogel, in the treatment of periodontal pockets.
- Trial name
- NCT07592377
- Testing
- H42® Collagen Hydrogel for the non-surgical treatment of periodontal pockets
- Where
- 2 sites in Italy
- Volunteers
- 38 people
- Sponsor
- Bioteck S.p.A.
Periodontal Diseases, Chronic Periodontitis
Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome
The purpose of this study was to demonstrate in patients with generalized chronic periodontitis that switching from cigarette smoking to using IQOS improves the response to periodontal therapy and the overall oral health status…
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Pocket, Tooth Mobility
- Trial name
- NCT03364751
- Testing
- IQOS, Cigarette
- Where
- 26 sites in Japan
- Volunteers
- 179 people
- Sponsor
- Philip Morris Products S.A.
Periodontitis
Study of Scaling and Root Planing With PerioWave Versus Scaling and Root Planing Alone in Chronic Periodontitis
This study is to determine whether scaling and root planing (SRP) followed by photodynamic disinfection results in improved outcomes that persist over time in adults with chronic periodontitis when compared with subjects with SRP…
- Trial name
- NCT00297531
- Testing
- PerioWave, Scaling and Root Planing
- Where
- 4 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Ondine Research Laboratories
Periodontitis
The Efficacy and Safety of PerioChip Plus (Flurbiprofen/Chlorhexidine) Formulation in the Therapy of Adult Periodontitis
The purpose of this study is to determine the effect of the placement of a PerioChip Plus (flurbiprofen/chlorhexidine - FBP/CHX) formulation versus PerioChip (chlorhexidine) formulation versus Flurbiprofen Chip formulation versus…
- Trial name
- NCT00425451
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Dexcel Pharma Technologies Ltd.
Chronic Periodontitis
Efficacy and Safety of a Commercially Available Injectable Hyaluronic Acid Dental Filler for Periodontal Pockets
This is a controlled, randomized, single-blinded, multicenter, prospective clinical study. In addition to the standard periodontal treatment procedure on all teeth that need to be treated, the 4 teeth with the deepest pockets…
- Trial name
- NCT02391974
- Testing
- PERIOSYAL FILL
- Where
- 3 sites in Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Moderate to Severe Chronic Periodontitis
Evaluation of the KLOX BioPhotonic OraLum Gel With a LED Curing Lamp in Moderate to Severe Chronic Periodontitis
Multicenter, prospective, interventional open case series study using a randomized split-mouth design in moderate to severe chronic periodontitis patients having half-mouth treated with the KLOX BioPhotonic OraLum gel with a LED…
- Trial name
- NCT02325570
- Testing
- KLOX BioPhotonic OraLum Gel, Scaling and Root Planing (SRP)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- KLOX Technologies Inc.
Periodontitis
Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis
The purpose of this study is to measure the antimicrobial effects of Arestin in subjects with moderate to advanced periodontal disease
- Trial name
- NCT00371332
- Testing
- Minocycline HCL Microspheres
- Where
- 5 sites in United States
- Volunteers
- 128 people
- Sponsor
- OraPharma
Chronic Periodontitis
Efficacy of a Probiotic Lozenges in Chronic Periodontitis Patients.
Periodontal disease is an infectious disease resulting in inflammation within supporting tissues of the teeth, progressive attachment loss, and bone loss.
- Trial name
- NCT02121665
- Testing
- Probiotic (Inersan)
- Where
- India
- Volunteers
- 42 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Chronic Periodontitis
A Study to Evaluate the Efficacy and Safety of ALH-L1005 in Patients With Chronic Periodontitis
The main objective of this study is to evaluate efficacy and safety of ALH-L1005 in patients with chronic periodontitis
- Trial name
- NCT04503746
- Testing
- ALH-L1005 600mg/day, ALH-L1005 1,200mg/day
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- AngioLab, Inc.
Chronic Periodontitis
Perio. Maint. With Diode LBR
The primary aim of this pilot study is to determine whether the test methods described feasibly achieve the goal defined for a future clinical study.
- Trial name
- NCT05276817
- Testing
- Epic Diode, HP
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Biolase Inc
Periodontitis
PerioWave Re-Treatment Protocol Compared to Scaling and Root Planing (SRP) and a Single Treatment With PerioWave
This is a pivotal, prospective, randomized, blinded, multicenter study to evaluate two treatments of photodynamic disinfection in adults with chronic periodontal disease.
- Trial name
- NCT00336661
- Testing
- PerioWave
- Where
- 2 sites in China
- Volunteers
- 105 people
- Sponsor
- Ondine Research Laboratories
Periodontitis
Long-term Safety of Minocycline in Patients With Gum Disease
This study will look at the safety of using the study medicine for a long time. It will see if the germs get used to the medicine, making it not work as well, if it's used by people with gum disease for a long time.
- Trial name
- NCT00668746
- Testing
- Minocycline HCl microspheres
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- OraPharma
Generalized Adult Periodontitis
The Efficacy and Safety of 2.5 mg Chlorhexidine Gluconate Chip (PerioChip®) in Frequent Treatment Versus Routine Treatment in Therapy of Adult Chronic Periodontitis
The purpose of this study is to assess the efficacy and the safety of Chlorhexidine Gluconate Chip (PerioChip®) in frequent treatment versus routine treatment in therapy of adult chronic periodontitis.
- Trial name
- NCT01249846
- Testing
- PerioChip ®
- Where
- Israel
- Sponsor
- Dexcel Pharma Technologies Ltd.
Periodontitis
Study of Scaling and Root Planing (SRP) With PerioWave vs. SRP Alone in Chronic Periodontitis
This study is to determine whether scaling and root planning (SRP) followed by photodynamic disinfection results in improved outcomes that persist over time in adults with chronic periodontitis when compared with subjects with…
- Trial name
- NCT00297518
- Testing
- PerioWave, Scaling and Root Planing
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Ondine Research Laboratories
Chronic Periodontitis
Efficacy of a Probiotic Lozenge (Inersan) in Patients With Chronic Periodontitis
Periodontal disease is a major cause of tooth loss in humans and is one of the most prevalent diseases associated with bone loss.
- Trial name
- NCT01870362
- Testing
- Probiotic (Inersan)
- Where
- India
- Volunteers
- 28 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Periodontal Diseases, Periodontitis
Home Use of Dual-light Photodynamic Therapy for Chronic Periodontitis
This early-stage research is designed to determine the efficacy of the Lumoral method in chronic periodontitis patients. Improved supragingival plaque control can help to also sustain the subgingival plaque management in the long…
- Conditions
- Periodontal Diseases, Periodontitis, Plaque, Dental, Plaque Induced Gingivitis
- Trial name
- NCT05425784
- Testing
- Lumoral treatment, Standard oral hygiene self care
- Where
- 3 sites in Finland
- Volunteers
- 41 people
- Sponsor
- Koite Health Oy
Periodontitis
The Efficacy and Safety of Flurbiprofen Chip Versus Chlorhexidine Chip (Periochip®) in Therapy of Adult Chronic Periodontitis
The purpose of the study is to assess efficacy and safety of Flurbiprofen Chip versus Chlorhexidine chip (Periochip®) in therapy of adult chronic periodontitis.
- Trial name
- NCT01040286
- Testing
- Flurbiprofen, Chlorhexidine
- Where
- Israel
- Sponsor
- Dexcel Pharma Technologies Ltd.
Periodontitis
SRP in Combination With PERIOWAVE in Comparison to SRP Alone in Chronic Periodontitis
This study is to determine whether scaling and root planning (SRP) followed by photodynamic disinfection results in improved outcomes that persist over time in adults with chronic periodontitis when compared with subjects with…
- Trial name
- NCT00296881
- Testing
- PERIOWAVE
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Ondine Research Laboratories