Clinical trials: Adult Periodontitis
Periodontitis
Nagasaki and Tokushima
we analyzed the relationship between oxidative stress, immunoglobulin G antibody titers, cytokines, and periodontitis through community-based study held in the Goto city, Japan.
- Trial name
- NCT01742728
- Where
- Japan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Tokushima
Localized Aggressive Periodontitis, Chronic Periodontitis
Tissue Alterations in Aggressive and Chronic Periodontitis
Present study intended to compare diseased and healthy sites in chronic and aggressive periodontitis with healthy individuals. The investigators suggest that even unaffected healthy sites of both chronic and aggressive…
- Trial name
- NCT03625414
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Chronic Periodontitis
A Clinical Trial of YH14642 in Patients With Chronic Periodontal Disease
This study is designed to evaluate the efficacy and the safety of YH14642 in Korea patients with chronic periodontitis, in order to investigate the recommended therapeutic dose.
- Trial name
- YH14642 (NCT01499225)
- Testing
- YH14642 500mg Tab, INSADOL[Zea mays L. extract] 35mg Tab, DENTISTA[Doxycycline hyclate] 20mg Cap
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- Yuhan Corporation
Periodontal Disease, Halitosis
"Study of Halitosis in Patients With Advanced Chronic Periodontitis"
The objective of this study was to evaluate whether short-term full mouth disinfection protocol could have a greater reduction in the levels of halitosis and volatile sulfur compound or not, when compared to quadrant-wise scaling…
- Conditions
- Periodontal Disease, Halitosis, Periodontitis
- Trial name
- HACP (NCT02368678)
- Testing
- Scaling and Root Planning (SRP), Full Mouth Scaling (FMS)
- Volunteers
- 30 people
- Sponsor
- Federal University of Minas Gerais
Periodontitis, Intrabony Periodontal Defect
MIST Versus M-MIST for the Treatment of Intrabony Defects
This is a 12-month longitudinal, double-blind, parallel-design randomized controlled clinical trial involving surgical therapeutic intervention (Phase 4).
- Conditions
- Periodontitis, Intrabony Periodontal Defect, Periodontitis, Chronic
- Trial name
- NCT06058923
- Testing
- M-MIST, MIST
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Chronic Periodontitis
Effect of Periodontal Treatment on Salivary Biomarkers
The investigators plan to recruit 40 healthy patients referred to the unit of Periodontology, diagnosed with generalized moderate - severe chronic periodontitis.
- Trial name
- NCT02159781
- Testing
- periodontal treatment - scaling and root planning
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Probiotics, Periodontitis
Efficacy of Supplementation With Probiotics as Adjuvant to Mechanical Treatment in Chronic Periodontitis
It aims to demonstrate the superiority of a 6-week supplementation with Lactibiane Buccodental compared to placebo, as adjunctive therapy in chronic periodontitis in patients with generalized chronic periodontitis
- Trial name
- NCT03554187
- Testing
- Ultrasonic periodontal Debridement, with appropriate device, Analyzes of periodontopathogenic bacteria, IL1B test
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- PiLeJe
Chronic Periodontitis
Decontaminant Agent in the Treatment of Chronic Periodontitis
In light of the controversy that are already approved but that however still exists regarding the efficacy and influence of the decontaminant tools for the management of Chronic Periodontitis (cp), the aim of this study was to…
- Trial name
- NCT02657096
- Testing
- Hybenx treatment (device), Scaling and Root Planing (SRP)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Messina
Rheumatoid Arthritis, Chronic Periodontitis
Estimation of Pentraxin3 and PGingivalis Levels in Patients With Knee Joint and Gum Diseases
Periodontitis and Rhematoid arthritis are chronic inflammatory diseases which share common risk factors The purpose of this study is to determine if Pentraxin 3 and Porphyromonas Gingivalis levels play an important role in the…
- Trial name
- EP3PGKG (NCT02503046)
- Testing
- Estimation of Pentraxin3, Estimation of P.Gingivalis levels
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Periodontitis
Photodynamic Therapy Plus Root Debridement in Gum Disease Treatment V2
Gum disease is a common disease, which affects 45% of the UK adult dentate population. It is caused by bacteria in dental plaque, which produces inflammation and a deepening of the natural crevice between the gum and the tooth…
- Trial name
- PDTV2 (NCT03270254)
- Testing
- light activated dye photodynamic therapy (PDT)
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Menopausal Patients, Chronic Periodontitis
Treatment of Periodontitis in Menopausal Patients
The goal of this clinical trial is to compare the effectiveness of polyunsaturated fatty acids (PUFAs) [omega-3] as an adjunctive treatment to scaling and root planing for menopausal women with periodontitis versus scaling and…
- Conditions
- Menopausal Patients, Chronic Periodontitis, Omega 3 Fatty Acids
- Trial name
- NCT06254118
- Testing
- Polyunsaturated Fatty Acids, olive oil
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Hadir F. El-Dessouky
Periodontitis, Adult
Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects
in this clinical trial, patients with periodontal defects will be treated with advanced platelet-rich fibrin in conjunction with open debridement
- Trial name
- NCT05730153
- Testing
- advanced PRF
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Periodontitis, Adult
Efficacy of Proanthocyanidins in Non-Surgical Periodontal Therapy
The aim of the study is to evaluate the efficacy of proanthocyanidins as an adjunctive periodontal therapy in patients with periodontitis. Recently proanthocyanidins were proposed as a viable adjunct to periodontal treatment.
- Trial name
- NCT05015387
- Testing
- Minimally invasive non-surgical therapy, Subgingival application of collagen hydrogels with proanthocyanidins, Collection of saliva samples
- Where
- Lithuania
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Chronic Periodontitis With Infra-bony Defects
Effect of Hyaluronic Acid in the Treatment of Periodontal Pockets
The aim of this study is to evaluate the effect of hyaluronic acid in the surgical treatment of periodontal pockets in people with gum disease. This research consists of clinical and radiographic studies.
- Trial name
- NCT02170857
- Testing
- Hyaluronic Acid
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Chronic Periodontitis
Intervention Study of Two Protocols for Non-surgical Treatment of Chronic Periodontitis
Treatment directed towards the control of periodontal infections is to about 90% non-surgical procedures. There is evidence from a large number of randomized controlled studies that the efficacy in terms of clinical outcomes of a…
- Trial name
- NCT02168621
- Testing
- Full-mouth ultrasonic debridement, Section-wise scaling and root planing
- Where
- Sweden
- Volunteers
- 800 people
- Sponsor
- Göteborg University
Periodontal Disease, Periodontal Bone Loss
Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials.
The present study is an effort to investigate the hypothesis that Platelet Rich Fibrin/Biphasic Calcium Phosphate may play a role in inhibiting osteoclasts differentiation and in bone loss.
- Conditions
- Periodontal Disease, Periodontal Bone Loss, Osteoclastic Bone Loss
- Trial name
- NCT03227367
- Testing
- other : PRF
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Chronic Periodontitis
Effect of Omega 3 on Periodontitis in Postmenopausal Women
The study was aimed to investigating changes in periodontal parameters and superoxide dismutase activity after root surface debridement with and without Omega 3 fatty acids (ω-3 FAs) supplementation in postmenopausal women.
- Trial name
- NCT02764879
- Testing
- Omega 3 fatty acids, scaling and root planing
- Volunteers
- 50 people
- Sponsor
- October 6 University
Periodontis, Aggressive Periodontitis
Single-cell and Spatial Transcriptomic Profiling of Gingival Tissues in Aggressive and Chronic Periodontitis: Deciphering Cellular Heterogeneity and Inflammatory Microenvironment Features
The goal of this observational study is to investigate cellular heterogeneity and inflammatory microenvironment features in gingival tissues from patients with aggressive periodontitis compared to chronic periodontitis and…
- Trial name
- NCT07487272
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Periodontitis
Autologous Alveolar Bone Marrow Mesenchymal Stem Cells for the Reconstruction of Infrabony Periodontal Defects
Systemically healthy periodontitis patients are recruited from new referrals to the Department of Periodontology and Biology of Implants, AUTh.
- Trial name
- PerioRegen (NCT02449005)
- Testing
- BM-MSCs/fibrin glue/collagen fleece, Fibrin glue/collagen fleece, Open flap debridement
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Chronic Periodontitis, Diabetes Type 2
Effect of Periodontal Therapy in the Systemic Status of Individuals With Chronic Periodontitis and Diabetes Type 2
This study will evaluate if periodontal mechanical treatment is capable to alter immunological and genetical parameters related to systemic health in patients with chronic periodontitis ant diabetes type 2.
- Trial name
- NCT02589314
- Testing
- Mechanical periodontal therapy, nonsurgical periodontal therapy
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Brasilia