Clinical trials: Adult Periodontitis
Chronic Periodontitis
Comparison of PRP & DFDBA vs. DFDBA in Intrabony Periodontal Defects
The purpose of this clinical trial is to compare the results in subjects with periodontitis using subjects own blood - Platelet-rich plasma (PRP) combined with bone graft material, namely, Demineralized Freeze - Dried Bone…
- Trial name
- NCT05886699
- Testing
- PRP combined with DFDBA, DFDBA
- Where
- India
- Volunteers
- 13 people
- Sponsor
- Government Dental College and Hospital, India
Chronic Periodontitis
Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis
This study was carried out in the Department of Periodontology and source of patient was be from the outpatient section of Tatyasaheb Kore Dental College \& Research Centre, New Pargaon.
- Trial name
- NCT03516370
- Testing
- Saccharomyces Boulardii 250 MG
- Where
- India
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Atherosclerosis, Chronic Periodontitis
Determining the Relationship Between the Atherosclerosis and Periodontopathogenic Microorganisms
Determine the relationship between the systemic indications of atherosclerosis by means of the change in the ratio of periodontopathogenic microorganisms following periodontal treatment of individuals who have been diagnosed with…
- Trial name
- NCT02977351
- Testing
- Non-surgical periodontal treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Periodontitis, Chronic, Periodontal Diseases
Effects of Antimicrobial Photodynamic Therapy on Regeneration of Class II Furcation Lesions
The aim of this study is to evaluate the additional effect of antimicrobial photodynamic therapy regeneration treatment of mandibular furcation lesions when associated to bovine bone and porcine collagen membrane.
- Conditions
- Periodontitis, Chronic, Periodontal Diseases, Periodontal Bone Loss
- Trial name
- NCT03264118
- Testing
- Scaling and root planing, Toluidine Blue O
- Where
- 2 sites in Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo
Generalized Chronic Periodontitis
Erbium Chromium: YSGG Laser Effect on Surgical Treatment of Chronic Periodontitis
Microbiological and Clinical assessment of Er,Cr:YSGG laser in conjunction to open flap debridement (OFD) in treatment of chronic periodontitis through real time PCR assay for quantification of total bacterial load.
- Trial name
- NCT03810560
- Testing
- laser device Er,Cr:YSGG laser
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- alaa
Chronic Periodontitis, Intrabony Periodontal Defect
Comparative Study of APRF/CGF Technology in GTR
Guided tissue regeneration(GTR) uses membranous materials to shield gingival epithelial cells and connective tissue cells which grow more rapidly, creating an effective closed space and time for periodontal ligament cells with…
- Trial name
- NCT04953260
- Testing
- APRF, CGF
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Periodontitis
Diode Laser Therapy As An Adjunct To Scaling And Root Planing
Laser therapy has been proposed as a novel treatment option in controlling subgingival microorganisms. This randomized controlled clinical trial evaluates the effect of 980nm diode laser as an adjunct to scaling and root planing…
- Trial name
- NCT03028727
- Testing
- Ultrasonic Scaling and root planing, 980 nm diode laser irradiation
- Volunteers
- 40 people
- Sponsor
- KLE Society's Institute of Dental Sciences
Chronic Periodontitis, Aggressive Periodontitis
IL-34 Levels in Various Types of Periodontitis
The objective of this study is to 1) identification of the impact of IL-34 on the pathogenesis of periodontal disease and determine whether any relationship among the existing levels of Gingival crevicular fluid (GCF) Interleukin…
- Trial name
- NCT04223869
- Testing
- non-surgical periodontal treatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Diabetes Mellitus, Type 2, Periodontitis, Adult
Evaluation of Chlorhexidine Gel Associated with Photodynamic Therapy in the Treatment of Chronic Periodontitis in Type 2 Diabetics
The objective of this clinical trial is to evaluate chlorhexidine gel associated with photodynamic therapy in the treatment of chronic periodontitis in Type 2 diabetics The main questions it aims to answer are: To evaluate if the…
- Conditions
- Diabetes Mellitus, Type 2, Periodontitis, Adult, Periodontitis
- Trial name
- NCT06469294
- Testing
- Control (C) - Saline Gel, Test (t) - Photodynamic therapy and 2% chlorexidine and 0,005% methylene blue
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Periodontal Diseases
Melatonin as an Adjunctive Therapy for Chronic Periodontitis.
Background: Melatonin is an endogenous indoleamine synthesized mainly by pineal gland and showed anti-inflammatory and antioxidant properties.
- Trial name
- NCT03368430
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Mansoura University
Periodontitis, Type2 Diabetes
Effect of Aspirin Vs Omega 3 Fatty Acid After Scaling and Root Planing in Type II Diabetic Patients With Chronic Periodontitis
The main aim and objective of this study is to compare the effectiveness of low dose aspirin vs omega 3 fatty acids as adjuvants to non-surgical periodontal therapy and also to evaluate the levels of pentraxin 3 and glycosylated…
- Trial name
- EAOFASRPDMCP (NCT03599401)
- Testing
- Scaling and root planing
- Where
- India
- Volunteers
- 42 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Periodontitis
Study of Scaling and Root Planing With PerioWave Versus Scaling and Root Planing Alone in Chronic Periodontitis
This study is to determine whether scaling and root planing (SRP) followed by photodynamic disinfection results in improved outcomes that persist over time in adults with chronic periodontitis when compared with subjects with SRP…
- Trial name
- NCT00297531
- Testing
- PerioWave, Scaling and Root Planing
- Where
- 4 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Ondine Research Laboratories
Generalized Moderate Chronic Periodontitis, Generalized Severe Chronic Periodontitis
Treatment of Periodontitis With Er:YAG Laser
The purpose of this research project is to gain information on the best and most comfortable way to treat the periodontal disease.
- Conditions
- Generalized Moderate Chronic Periodontitis, Generalized Severe Chronic Periodontitis, Periodontal Diseases
- Trial name
- NCT03628872
- Testing
- Scaling and root planing, Er:YAG Laser, Hand instruments
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Columbia University
Chronic Periodontitis
1.2% Atorvastatin and 1.2% Simvastatin in Treatment of Chronic Periodontitis
Background: Statins are the recently evolved agents that aid in periodontal regeneration and ultimately attaining periodontal health.
- Trial name
- NCT02060032
- Testing
- 1.2% Atorvastatin local drug delivery, 1.2% simvastatin local drug delivery
- Volunteers
- 96 people
- Sponsor
- Government Dental College and Research Institute, Bangalore
Chronic Periodontitis, Smoking
Adjunct Photodynamic Therapy in Chronic Periodontitis Among Cigarette-smokers.
This study evaluates the efficacy of scaling and root planing with and without adjunct antimicrobial photodynamic therapy (aPDT) in the treatment of chronic periodontitis (CP) among cigarette-smokers and never-smokers.
- Trial name
- NCT03308019
- Testing
- Photodynamic therapy, Scaling and root planing (SRP)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- King Saud University
Chronic Periodontitis
Complex Phytoadaptogenes in Chronic Periodontitis Treatment.
A randomized controlled clinical trial was done to assess the periodontal status of the individuals baseline followed by by including chronotherapy with complex phytoadaptogens (CFA) into the non-surgical periodontal treatment…
- Trial name
- NCT04623164
- Testing
- Cocktail from complex phytoadaptogens (CFA), Standard non-surgical periodontal treatment (NSPT)
- Where
- Russia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vladikavkaz Scientific Center of the Russian Academy of Sciences
Chronic Periodontitis
Omega-3 Fatty Acids in Chronic Periodontitis.
Omega 3 fatty acids is one such dietary supplement, known to modulate the host response in chronic conditions like cardiovascular diseases, rheumatoid arthritis, ischemic cerebrovascular diseases, osteoporosis by producing…
- Trial name
- omega3 (NCT01997853)
- Testing
- Omega 3 fatty acid
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontitis, Diabetes Mellitus
Comparing the Efficacy of Metronidazole and Minocycline Gels for the Treatment of Diabetic Periodontitis Patients
This clinical study randomized 380 diabetic chronic periodontitis patients into 4 groups: scaling and root planning alone (group I), scaling and root planning plus metronidazole gel (group II), scaling and root planning plus…
- Trial name
- NCT06027151
- Testing
- 1ml of 1% metronidazole gel, 1ml of 2% minocycline gel, 1ml of combination of 1% metronidazole gel and 2% minocycline
- Where
- Pakistan
- Volunteers
- 380 people
- Sponsor
- Riphah International University
Chronic Periodontitis
Locally Delivered Atorvastatin & Rosuvastatin for Treatment of Furcation Defects in Chronic Periodontitis
Statins are one of the lipid lowering drugs that help in reducing cholesterol levels in the body by specifically inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase; which is a rate limiting enzyme for cholesterol…
- Trial name
- NCT02800902
- Testing
- Rosuvastatin, Atorvastatin
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Periodontitis
The Efficacy and Safety of PerioChip Plus (Flurbiprofen/Chlorhexidine) Formulation in the Therapy of Adult Periodontitis
The purpose of this study is to determine the effect of the placement of a PerioChip Plus (flurbiprofen/chlorhexidine - FBP/CHX) formulation versus PerioChip (chlorhexidine) formulation versus Flurbiprofen Chip formulation versus…
- Trial name
- NCT00425451
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Dexcel Pharma Technologies Ltd.