Clinical trials: Adult Periodontitis
Chronic Periodontitis
Efficacy of Herbal Dentifrice in Treatment of Chronic Periodontitis
The study will be a single center, longitudinal prospective, triple blind (investigators, patients and statistician), randomized design.
- Trial name
- NCT06043687
- Testing
- Dentifrice Paste
- Where
- India
- Volunteers
- 75 people
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Chronic Periodontitis, Diabetes Mellitus
Effects of Adjunct Photodynamic Therapy in the Treatment of Type 2 Diabetic Patients With Chronic Periodontitis
Periodontal Diseases are considered the sixth complication of Diabetes Mellitus (DM). This close relationship between both diseases is characterized by mutual influence.
- Trial name
- NCT02627534
- Testing
- Ultrasonic debridement, Antimicrobial photodynamic therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Chronic Periodontitis
Evaluation of Amnion Chorion Membrane and Demineralized Bone Matrix Putty Allograft in Periodontal Intrabony Defects
A clinical and radiographic evaluation of 2 regenerative techniques, bioresorbable membrane and bone allograft for management of periodontal intrabony defects.
- Trial name
- NCT02679209
- Testing
- Demineralized bone matrix in putty form, Amnion chorion membrane
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Periodontitis
Clinical and Radiographic Evaluation of Doxycycline and Atorvastatin Loaded Chitosan Nanoparticles as an Adjunctive to Scaling and Root Planning in the Management of Chronic Periodontitis. A Randomized Controlled Clinical Trial.
Chronic periodontitis is one of the most prevalent inflammatory diseases affecting the tooth-supporting structures and is characterized by progressive clinical attachment loss and alveolar bone resorption resulting from a complex…
- Trial name
- NCT07634341
- Testing
- Doxycycline and Atorvastatin loaded Chitosan nanoparticles local drug
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Fayoum University
Moderate to Severe Chronic Periodontitis
Evaluation of the KLOX BioPhotonic OraLum Gel With a LED Curing Lamp in Moderate to Severe Chronic Periodontitis
Multicenter, prospective, interventional open case series study using a randomized split-mouth design in moderate to severe chronic periodontitis patients having half-mouth treated with the KLOX BioPhotonic OraLum gel with a LED…
- Trial name
- NCT02325570
- Testing
- KLOX BioPhotonic OraLum Gel, Scaling and Root Planing (SRP)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- KLOX Technologies Inc.
Chronic Periodontitis
CBD Effects on Periodontal Health of Patients With Chronic Periodontitis
The suppression of chronic periodontitis after application of dental gel and toothpaste containing cannabidiol (CBD) will be evaluated.
- Trial name
- Stoma-CBD (NCT05498012)
- Testing
- Cannabidiol dental gel, Cannabidiol toothpaste
- Where
- Czechia
- Volunteers
- 90 people
- Sponsor
- Palacky University
Periodontitis
The Effect of Daily Dietary Intake of Dried Juice Concentrates of Fruit, Vegetables and Berries Upon Outcomes of Chronic Periodontitis
The objective of this study is to determine whether enhanced micronutrient intake in the form of fruit, vegetable and berry juice powder (FVB) concentrate, improves clinical outcomes in chronic periodontitis patients prior to…
- Trial name
- ENURGISE (NCT01229631)
- Testing
- Juice plus+
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 108 people
- Sponsor
- Birmingham Community Healthcare NHS
Halitosis
Effect of Probiotic Lozenges on Halitosis in Patients With Chronic Periodontitis
The purpose of this study is to determine whether Lactobacillus reuteri-containing lozenges (Prodentis) are effective in treatment of halitosis in patients with chronic periodontitis.
- Trial name
- NCT02789436
- Testing
- L. reuteri Prodentis® lozenges
- Where
- Croatia
- Volunteers
- 30 people
- Sponsor
- University of Zagreb
Periodontitis, Adult
Cleansing Efficacy of Waist-shaped Interdental Brushes.
The aim of the present randomized and single-blinded cross-over study was to compare the cleansing efficacy of waist-shaped interdental brushes with that of cylindric interdental brushes in interproximal sites.
- Trial name
- Waist-shaped (NCT03851757)
- Testing
- waist-shaped interdental brush, cylindric interdental brush
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University Innsbruck
Chronic Periodontitis, Type 2 Diabetes Mellitus
Chronic Periodontitis Microbiota in Type 2 Diabetes Mellitus Patients
This study is a retrospective comparative evaluation of six main periodontal pathogens and total bacterial load in chronic periodontitis patients affected or not by type 2 diabetes mellitus by polymerase chain reaction analysis.
- Trial name
- NCT03786133
- Testing
- Analysis of microbiological tests
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Bologna
Periodontal Diseases
LED Light As An Adjunct Treatment Modality of Periodontal Diseases
By promoting the cellular activities, it has been shown that the low-level laser therapy (LLLT) is able to accelerate the wound healing, reduce gingival inflammation, relief the discomfort, and serve as an adjunct to the…
- Trial name
- NCT03557814
- Testing
- LED appliance during mechanical debridement, LED appliance after mechanical debridement, Mechanical debridement alone
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Periapical Periodontitis
Adrenomedullin Upregulation in Apical Periodontitis
The aim of the present study was to investigate the relationship between Apical periodontitis (AP) severity and inflammatory markers (IL-12, TNF-alpha), and Mid-Regional Pro Adrenomedullin (MR-proADM) in patients with AP.
- Trial name
- NCT05297747
- Testing
- Apical periodontitis, Chronic periodontitis
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Chronic Periodontitis
Grape Seeds Extract Gel as an Adjunct for the Treatment of Chronic Periodontitis
The aim of this study was to formulate a mucoadhesive gel of grapes seed extract (GSE) followed by short-term clinical study for the effectiveness of this gel onto the pocket depth (PD), plaque index (PI), gingival index (GI)…
- Trial name
- NCT02767115
- Testing
- 2% GSE mucoadhesive gel, GSE free mucoadhesive gel
- Where
- Saudi Arabia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Chronic Periodontitis
Full-mouth Treatment Approaches in Severe Chronic Periodontitis.
This study aimed to compare the effects of full-mouth disinfection (FMD) and full-mouth ultrasonic debridement (FMUD) on clinical, microbiologic and biochemical parameters with conventional quadrant-wise scaling and root planning…
- Trial name
- NCT04038801
- Testing
- Quadrant-wise scaling and root planning (Q-SRP), Full-mouth ultrasonic debridement (FMUD), Full-mouth disinfection (FMD)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Periodontitis
Prevalence Of Periodontitis Stage III & IV
The study is a cross-sectional survey investigating the prevalence of Periodontitis stage III \& IV in Egyptian dental patients attending the oral diagnosis clinic at faculty of Dentistry, Cairo University
- Trial name
- NCT03779763
- Where
- Egypt
- Volunteers
- 750 people
- Sponsor
- Cairo University
Periodontitis
Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis
The purpose of this study is to measure the antimicrobial effects of Arestin in subjects with moderate to advanced periodontal disease
- Trial name
- NCT00371332
- Testing
- Minocycline HCL Microspheres
- Where
- 5 sites in United States
- Volunteers
- 128 people
- Sponsor
- OraPharma
Dental Implantation, Missing Teeth
The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness
Scientists do research to answer important questions which might help change or improve the way we do things in the future. The investigators know that using Enamel Matrix Derivatives results in thicker gum tissues around teeth.
- Conditions
- Dental Implantation, Missing Teeth, Periodontitis, Adult, Mucositis
- Trial name
- NCT07053969
- Testing
- Enamel Matrix Derivative
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Carotid Stenosis, Mild Cognitive Impairment
Dental Carotid Cognitive Study
Periodontal Disease (PD) is present in 60+% of adults >65 years and is associated with tobacco smoking, diabetes, and atherosclerosis that worsen inflammation, comorbidities common in older people with mild to moderate cognitive…
- Conditions
- Carotid Stenosis, Mild Cognitive Impairment, Periodontitis
- Trial name
- NCT03755362
- Testing
- Standard Treatment, Intensive Treatment
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Maryland, Baltimore
Adult Periodontitis
Clinical Trials of Regeneration for Periodontal Tissue
Adult periodontitis is a chronic infective disease affecting the periodontium. Periodontitis induce the destruction of attachment apparatus of teeth, resulting in periodontal pocket formation and teeth loss.
- Trial name
- NCT00221130
- Testing
- surgical operation of cell transplantation
- Where
- Japan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Chronic Periodontitis
Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.
This research aims to evaluate the effectiveness of intentional replantation (IR) as a treatment for single-rooted teeth diagnosed as hopeless due to true periodontic lesions.
- Trial name
- NCT06893107
- Testing
- Intentional Replantation
- Where
- United Arab Emirates
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Fujairah