Clinical trials: Advanced Age
Chronic Diseases in Older Adults, Malnutrition
Elderly Health Profile in a Rural Village of Assiut
This study aims to assess the health, nutrition, functional status, and quality of life of older adults living in Al-Boura village in Assiut, Egypt.
- Conditions
- Chronic Diseases in Older Adults, Malnutrition, Frailty, Functional Decline Geriatric Health
- Trial name
- RURAL-AGE (NCT07263087)
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Assiut University
Rational Drug Use
Rational Drug Use in Elderly People
Irrational drug use, which is an important public health problem worldwide, is common in the elderly. While irrational drug use negatively affects all age groups, it poses a significant threat to the health of the elderly.
- Trial name
- NCT05397847
- Testing
- Education, Rational Drug Use Guide, Medicine Box
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Fall, Gait, Unsteady
The Brain Stimulation and Physical Therapy Study
This pilot work will determine the feasibility of tDCS intervention as an effective adjunct intervention to PT aimed at improving gait, balance, and mobility in older adults at risk of falling.
- Conditions
- Fall, Gait, Unsteady, Aging, Accidental Fall
- Trial name
- NCT04181658
- Testing
- Real tDCS and Physical Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hebrew SeniorLife
Pneumococcal Vaccine Adverse Reaction
Post-marketing Safety Evaluation of Pneumococcal Vaccines Among Children and Elderly Adults.
The purpose of this observational study is to examine the risk of adverse events following vaccination with 10 or 13-valent pneumococcal conjugate vaccine (PCV10 or PCV13) among infants or children age <59 months and 23-valent…
- Trial name
- NCT04551248
- Testing
- 10 or 13-valent pneumococcal conjugate vaccine, 23-valent pneumococcal polysaccharide vaccine, Influenza vaccine
- Where
- South Korea
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Sungkyunkwan University
Depression
Online Peer Networked Collaborative Learning for Managing Depressive Symptoms
The goal of this field trial is to tailor and test a web-based intervention in adults 65 years of age or older. Two versions of the web-based intervention have been created and will be tested--one with an online social network…
- Trial name
- MoodTech (NCT02841787)
- Testing
- iCBT for late life depression
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Northwestern University
Depression, Elderly
Collaborative Care for Depressed Elderly in Korea
Late-life depression is associated with physical limitations, greater functional impairment, increased utilization and cost of health care, and suicide.
- Conditions
- Depression, Elderly, Korean, Collaborative Care
- Trial name
- NCT01626716
- Testing
- care management
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- National Clinical Research Coordination Center, Seoul, Korea
COVID-19, Chronic Bronchitis
Immunogenicity and Safety of a Third Dose and Immune Persistence of BBIBP-Corv Vaccine in Elderly People With Chronic Bronchitis and COPD
Evaluation of immunogenicity, safety and persistence of the subjects aged 60 years and above with chronic bronchitis and chronic obstructive pulmonary disease received the third dose of inactivated COVID-19 vaccine .
- Conditions
- COVID-19, Chronic Bronchitis, COPD
- Trial name
- NCT05104216
- Testing
- Inactivated COVID-19 vaccine
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China National Biotec Group Company Limited
Sarcopenia
Evaluation of Sarcopenia in Elderly at the Emergency Department
The goal of this observational study is to evaluate in elderly patients for the frequency of sarcopenia and its relationship with mortality in a university hospital. The main questions it aims to answer are; 1.
- Trial name
- NCT05567549
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ege University
Cerebral Hypoxia, Postoperative Delirium
Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery
The aim of this study is to distinguish possible differences in frequency of delirium after Volatile Induction and Maintenance of Anesthesia and Total Intravenous Anesthesia in case of undeliberate cerebral desaturation during…
- Trial name
- NCT02133638
- Testing
- Sevoflurane, Propofol
- Where
- Russia
- Volunteers
- 130 people
- Sponsor
- Negovsky Reanimatology Research Institute
Geriatric, Virtual Reality
Effects of Immersive Virtual Reality on Physical Function, Fall-Related Outcomes, Fatigue, and Quality of Life in Older Adults
To investigate the effectiveness of an immersive virtual reality intervention on physical fitness, balance, physical activity level, risk of falling, fear of falling, fatigue, and quality of life in older adults compared to an…
- Trial name
- NCT07007026
- Testing
- Immersive Virtual Reality, Traditional Home-based Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Eastern Mediterranean University
Healthy
Elderly Consumer Survey
This study is a cross-sectional study, aiming to recruit 200 community-dwelling elderly, aged 60 years and above. Recruitments will be made from St. Luke's ElderCare's (SLEC) active aging hubs around Singapore.
- Trial name
- NCT07296978
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Technology
Intestinal Inflammation, Metabolic Disease
The Role of Regular Physical Activity in Enhancing Metabolic Health, Reducing Inflammation, and Improving Gut Function
The goal of this clinical trial is to learn if regular physical activity can improve metabolic health, reduce inflammation, and decrease gut permeability in individuals aged 50 and older.
- Trial name
- NCT06606678
- Testing
- Exercise
- Where
- Poland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Airway Management, Laryngeal Mask Airway Insertion Skill
The Effect of Ultrasonographic Airway Measurements and Anatomical Differences on Laryngeal Mask Placement in Young and Older Adults
This prospective observational study aims to compare ultrasonographic upper-airway measurements and age-related anatomical differences between young adults (18-40 years) and older adults (>65 years), and to evaluate their effects…
- Trial name
- NCT07776847
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people
- Sponsor
- Duzce University
Mental Health (Depression), Mental Health and General Well-being
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
The goal of this clinical trial is to evaluate whether a virtual reality (VR) based social platform can improve mental health and social connection for older adults who receive in-home care.
- Conditions
- Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being
- Trial name
- Thrive at Home (NCT07835568)
- Testing
- Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Aging, Sarcopenia
Effect of Immunocal® With Exercise Versus Casein With Exercise on Aging Processes in Elderly Persons
Aging is typically associated with a decrease in skeletal muscle mass and muscle function, which contributes decisively to disability in old age and to the loss of quality of life.Resistance exercise can increase muscle strength…
- Trial name
- NCT00935610
- Testing
- Immunocal, Casein
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Immunotec Inc.
Aging, Age-related Cognitive Decline
The Effects of Strawberry Supplementation on Memory and Gait Among Over-weight Older Adults
This study is being conducted to assess the effect of dietary strawberry supplementation on cognition and mobility in obese middle-aged and older adults.
- Conditions
- Aging, Age-related Cognitive Decline, Obesity
- Trial name
- NCT03162913
- Testing
- Strawberry
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- USDA Human Nutrition Research Center on Aging
Hip Fracture
Postoperative Blood Transfusion for Frail Elderly With Hip Fracture
Elderly with hip fractures are often frail and discharged from hospital after few days of hospitalisation. Hip fracture surgery is often associated with blood loss, where the patient is at risk of developing anaemia.
- Trial name
- NCT01102010
- Testing
- Blood transfusion
- Where
- Denmark
- Volunteers
- 284 people
- Sponsor
- University of Aarhus
Cholecystectomy, Laparoscopic, Choledocholithiasis
ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly
The goal of this study is to compare safety and efficacy of laparoscopic cholecystectomy versus wait-and-see policy after endoscopic removal of common bile duct stones in elderly.
- Conditions
- Cholecystectomy, Laparoscopic, Choledocholithiasis, Cholelithiasis
- Trial name
- COFFEE (NCT07001423)
- Testing
- Laparoscopic cholecystectomy
- Where
- 12 sites in Finland
- Volunteers
- 400 people
- Sponsor
- Helsinki University Central Hospital
Ischemic Stroke
Serial ECG Versus Holter to Detect Atrial Fibrillation in Elderly Ischemic Stroke Patients
Paroxysmal atrial fibrillation is often undetected because characteristics such as short duration, episodic, and frequently asymptomatic nature make it challenging to diagnose at the bedside, leading to suboptimal secondary…
- Trial name
- NCT02578979
- Testing
- Electrocardiogram, Holter
- Where
- 6 sites in Taiwan
- Volunteers
- 826 people
- Sponsor
- Chang Gung Memorial Hospital
Aging
Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women
The proposed studies will assess 1) the mechanisms for the age-related increase in fatigability during dynamic exercise (Aims 1 and 2) and 2) the effectiveness of high-velocity resistance training coupled with blood flow…
- Trial name
- NCT03888040
- Testing
- Exercise
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Marquette University