Clinical trials: Adverse Childhood Experience
Chronic Pain, Central Sensitisation
Childhood Adversity, Inflammatory Reactivity and Persistent Pain
The goal of this observational study is to investigate how adverse experiences during childhood are linked to people experiencing persistent pain and fatigue in adulthood. The questions the investigators aim to answer are: 1.
- Conditions
- Chronic Pain, Central Sensitisation, Immune Response, Adverse Childhood Experiences
- Trial name
- CAIR (NCT06127693)
- Testing
- Tetravalent Influenza Vaccine, High-frequency electrical stimulation
- Where
- South Africa
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Stress, Childhood Obesity
Healing Experiences of Adversity Among Latinos (HEALthy4You)
Healing Experiences of Adversity Among Latinos (HEALthy4You) is a project funded by the California Initiative for the Advancement of Precision Medicine ("Advancing a Precision Population Health Approach to ACEs to Reduce Health…
- Trial name
- NCT05676281
- Testing
- Healthy Together (Control), Healthy Together + Promotora Support, Healthy Together + Parenting Training
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alcohol Use Disorder, Trauma, Psychological
Adverse Childhood Experiences in Alcohol Use Disorder
Adverse childhood experiences (ACE) and their relation to the development of an alcohol use disorder (AUD) will be measured with functional magnetic resonance imaging (fMRI).
- Trial name
- NCT05048758
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Stress, Psychological, Stress, Emotional
Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale
Childhood adversity in the form of maltreatment and household dysfunction is the most important risk factor for psychopathology as well as a major risk factor for a host of medical disorders.
- Trial name
- MACEStress (NCT06152549)
- Testing
- Maltreatment and Abuse Chronology of Exposure Scale as a stress challenge, Standardized Maths and Verbal Questions such as the ones used in SATs, Chronology of Perceived Discrimination Scale (CPDS)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Adverse Childhood Experiences, Domestic Violence
The Impact of an Adapted Version of the Strengthening Families Program on IPV Among Caregivers and ACEs Among Children
Adverse childhood experiences (ACEs) are unfortunately common and the known outcomes are concerning. However, very little is currently known about programs that may prevent ACEs among children, such as witnessing intimate partner…
- Trial name
- NCT05129501
- Testing
- Experimental
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Psychological Distress, Adverse Childhood Experience
EMI for Reducing Psychological Distress in Young Adults With Multiple ACEs: A RCT Study
This study is a two-arm randomized controlled trial designed to evaluate the effectiveness of an ecological momentary intervention (EMI) in reducing psychological distress among young adults with multiple adverse childhood…
- Trial name
- NCT07885579
- Testing
- EMI
- Volunteers
- 100 people
- Sponsor
- Peking University
Mental Health Issue, Adverse Childhood Experience
Chinese Community Sample of Hierarchical Model of Psychopathology
By validating Hierarchy Model of psychopathology(HiTOP) in Chinese community samples, this study aims for illumating the problem of diagnostic heterogeneity and high comorbidity within existing psychiatric classification systems…
- Trial name
- NCT06105970
- Testing
- No intervention
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Depression in Adolescence, Adverse Childhood Experiences
Shaping Actions and Responses to Emotions
The primary objective of this research is to examine two brief interventions for depression, Behavioral Activation (BA), and Problem Solving Therapy (PST), to investigate whether exposure to adverse childhood experiences…
- Trial name
- ShARE (NCT04719949)
- Testing
- Behavioral Activation (BA) Therapy, Problem Solving Therapy (PST)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Pittsburgh
Life Change Events, Loneliness
Me and the Others: Expectations and Evaluation of Social Relationships
Chronic and pervasive loneliness has been identified as an important factor in the relationship between adverse childhood experiences (ACE) (e.g. abuse and neglect) and mental disorders.
- Trial name
- NCT03764566
- Testing
- Questionnaires
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim