Clinical trials: Adverse Childhood Experiences
Adverse Childhood Experiences, Developmental Risk
Growing Up in Multifactorial Risk Conditions
The perinatal period brings significant physiological and emotional changes in mothers, linked to pregnancy, childbirth, and caring for a newborn.
- Conditions
- Adverse Childhood Experiences, Developmental Risk, Psychomotor Development Disorders, Neurodevelopmental Disorders
- Trial name
- CORE (NCT07477899)
- Testing
- Home visiting programme
- Where
- Italy
- Volunteers
- 352 people
- Sponsor
- IRCCS Eugenio Medea
Stress, Psychological Stress
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
The aim of the Everyday Moments of Mindfulness (EMMI) study is to test whether brief mindfulness-based practices will improve daily psychological stress responses in women (age 30-60) who report a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMI (NCT04606199)
- Testing
- Mindfulness-based intervention, up to 5 minutes 0-3 times/day
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stress, Emotional, Stress-related Mental Disorders
Effects of Parent-Adolescent Joint Interventions for Adolescents With Adverse Childhood Experiences
The study aims to examine the effectiveness of joint parent-adolescent intervention in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as measured by the…
- Conditions
- Stress, Emotional, Stress-related Mental Disorders, Adverse Childhood Experiences
- Trial name
- EASY-PEP (NCT06619821)
- Testing
- Emotiaonl skill enhancement, PCE promotion, Psychoeducation
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Adverse Childhood Experiences
Increasing Use of Earned Income Tax Credit (EITC) in New Mexico
Purpose of the Proposed Project. The literature makes clear that poverty and financial hardship and lack of social support are significant risk factors that create a household environment conducive to Adverse Childhood…
- Trial name
- NCT04961177
- Testing
- EITC & ACEs Training, EITC Outreach & Screening, Assistance with EITC
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of New Mexico
Adverse Childhood Experiences
Journey of Hope in Appalachia: Supporting Resilience in the Region's Youth
Rural youth have heightened exposure to adverse childhood experiences (ACES) such as poverty, social isolation, chronic hunger, and drug use in the home.
- Trial name
- JOHA (NCT04096937)
- Testing
- Focus groups
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gia Mudd
Healthy
Oxytocin Administration and Emotion Recognition Abilities in Adults Reporting Adverse Childhood Experiences
This study evaluates whether intranasal administration of a single dose of oxytocin improves the ability to recognize emotional states.
- Trial name
- NCT03335085
- Testing
- Oxytocin
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Fibrinogen Abnormality, Telomere Length, Mean Leukocyte
Pediatric ACEs Screening and Resiliency Study
Stressful and traumatic experiences in childhood (Adverse Childhood Events, or ACEs) have been associated with poor health outcomes that extend into adulthood.
- Conditions
- Fibrinogen Abnormality, Telomere Length, Mean Leukocyte, Atopic, Acute Infection
- Trial name
- PEARLS (NCT04182906)
- Testing
- Care Coordination, Resiliency Clinic, Usual Care
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Adverse Childhood Experiences
Building Resilient Families
Prior research suggests that it is possible to improve health outcomes in children with ACEs through multi-component interventions.
- Trial name
- NCT05388864
- Testing
- Three-Tier Model
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Adverse Childhood Experiences
Family Resilience Initiative Research Program
University Le Bonheur Pediatric Specialists (ULPS) and Le Bonheur Community Health and Well-Being, Maternal Child Department, have started the Family Resilience Initiative (FRI) in the ULPS General Pediatrics Clinic.
- Trial name
- NCT04018404
- Testing
- FRI CLINICAL PROGRAM
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Le Bonheur Children's Hospital
Adverse Childhood Experiences
Implementation of Adverse Childhood Experiences (ACEs) Policy
Adverse Childhood Experiences (ACEs) are pervasive among children with 45% experiencing at least one ACE and 10% experiencing three or more, placing them at high risk for toxic stress and symptomatology.
- Trial name
- NCT04916587
- Testing
- Implementation Strategy of ACEs Screenings, Usual Care
- Where
- United States
- Volunteers
- 7,645 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Overweight, Obesity
Relationship of Adverse Childhood Experiences to Overweight and Obesity
The purpose of this study is to determine if there is an association between a variety of adverse childhood experiences and overweight and obesity.
- Trial name
- NCT00632346
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Chronic Pain, Adverse Childhood Experiences
Traumatic Events in Childhood, Attachment, Pain Perception, Epigenetic Marks, Quality of Life and Resilience.
In the present research study, aiming to explore the links between several psychological factors and chronic pain, the research seeks to develop an inclusive framework to investigate the role of adverse childhood experiences…
- Conditions
- Chronic Pain, Adverse Childhood Experiences, Attachment Styles, Chronic Stress
- Trial name
- NCT06077097
- Testing
- Biological samples
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University of Lorraine
Autism Spectrum Disorder, Adverse Childhood Experiences
Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition
Using a metabolomics approach in combination with eye-tracking data, this research study proposes to gather evidence from two interrelated body systems (gut and brain) in order to assess how the microbiome is involved in stress…
- Conditions
- Autism Spectrum Disorder, Adverse Childhood Experiences, Stress Reaction
- Trial name
- NCT06269614
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Trauma and Stress-related Disorders, Food Insecurity
MISAPSY: Childhood Maltreatment, Food Insecurity, Psychological Distress and Professional Integration Among Socioeconomically Disadvantaged Young Adults
The MISAPSY study (Childhood Maltreatment, Food Insecurity, Psychological Distress and Professional Integration Among Socioeconomically Disadvantaged Young Adults) aims to model the complex interrelations between child…
- Conditions
- Trauma and Stress-related Disorders, Food Insecurity, Child Maltreatment, Psychological Distress
- Trial name
- PRESPA (NCT07427524)
- Testing
- Food Assistance, Psychological Follow-Up
- Where
- 6 sites in France
- Volunteers
- 70 people
- Sponsor
- University of Lorraine
Early Life Adversity, Caregiver Stress
The Resilience Clinic Evaluation
Early life adversity can affect children's physical and mental health. The Resilience Clinic is a support program for young children and their caregivers who have been exposed to significant adversity, aiming to prevent the…
- Trial name
- NCT05690256
- Testing
- Resilience Clinic, Enhanced primary care
- Where
- 4 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Immunity, Cytokine Levels
Analysis of Psychoneuroimmunological Parameters of Health in Specific Population Groups in Slovakia
This study aims to investigate the links between psychological and biological immunity from the perspective of psychology, epidemiology, and immunology in a general population study sample as well as in a specific group of people…
- Conditions
- Immunity, Cytokine Levels, Psychological Adaptation, Resilience
- Trial name
- APNIP (NCT07070180)
- Where
- 3 sites in Slovakia
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Comenius University
Psychological Distress, Adverse Childhood Experience
EMI for Reducing Psychological Distress in Young Adults With Multiple ACEs: A RCT Study
This study is a two-arm randomized controlled trial designed to evaluate the effectiveness of an ecological momentary intervention (EMI) in reducing psychological distress among young adults with multiple adverse childhood…
- Trial name
- NCT07885579
- Testing
- EMI
- Volunteers
- 100 people
- Sponsor
- Peking University
Emotion Regulation, Adverse Childhood Experience
Paired Emotion Reading Improves Emotion Regulation in Rural Children With ACE
The goal of this study is to explore the feasibility and effectiveness of the online Paired Emotion Reading Intervention (PERI) on the emotion regulation of rural children with adverse childhood experiences (ACE), as compared…
- Trial name
- NCT06505629
- Testing
- the online Paired Emotion Reading Intervention (PERI), the online Paired General Reading Intervention (PGRI)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University
Adverse Childhood Experiences
The ACCEPT Study: Improving the Process of Disclosing Adverse Childhood Experiences in Community Mental Health
Experiences of abuse, neglect, domestic violence, severe bullying and community violence in childhood are very common among people who use mental health services.
- Trial name
- NCT06477380
- Testing
- ACCEPT intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King's College London
Adverse Childhood Experiences, Mindfulness
Approaches That Support Mental Health in Post-secondary Students With Adverse Childhood Experiences
The objective of this study is to understand the prevalence of adverse childhood experiences (ACE) in students and to determine whether Mindfulness based stress resilience training (MBSR) is effective for promoting mental health…
- Conditions
- Adverse Childhood Experiences, Mindfulness, Students
- Trial name
- ACE (NCT03836456)
- Testing
- Mindfulness-based Stress Resilience Training, Health Enhancement Program
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dalhousie University