Clinical trials: Adverse Drug Interaction
- Condition Adverse Drug Interaction
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Adult, Drug Interactions
Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants
The primary purpose of the study is to characterize the safety profile of lorlatinib in the presence of a moderate CYP3A4/5 inducer, modafinil.
- Conditions
- Adult, Drug Interactions, Healthy Volunteers, Humans
- Trial name
- NCT03961997
- Testing
- Lorlatinib 50 mg, Lorlatinib 75 mg, Lorlatinib 100 mg
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Volunteer
A Study to Assess Adverse Events and How Single and Multiple Ascending Doses of ABBV-903 Move Through the Body in Healthy Adults
The purpose of this study is to evaluate adverse events and tolerability of single and multiple doses of ABBV-903, and to assess how the drug moves through the body in healthy adult volunteers.
- Trial name
- NCT05691699
- Testing
- ABBV-903, Itraconazole
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- AbbVie