Clinical trials: Aesthetics
Abdominoplasty
In-vivo Analysis of a Fractional CO2 Laser System (eMatrixCO2) Intended for Treatment of Soft Tissue
This study will: Evaluate the in vivo effects of treatment with eMatrixCO2 and to determine the dynamics of their development over time following treatment.
- Trial name
- eMatrixCO2 (NCT01026662)
- Testing
- Ablation and skin resurfacing, eMatrixCO2
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Hirsutism, Hypertrichosis
Enhanced Safety Laser Hair Removal System
The purpose of this study is to determine whether a new laser system provides better safety and efficacy in hair removal than existing lasers.
- Trial name
- NCT00441948
- Testing
- Peterio
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Scilex Ltd.
Dental Caries
Trial of a New NuSmile ZR Esthetic Primary Molar Crown
The hypothesis to be tested is that NuSmile ZR esthetic primary molar crowns perform similarly to an established Stainless Steel primary molar crown (3M ESPE) for restoration of primary molar teeth.
- Trial name
- NCT01919515
- Testing
- ZR Crown, Stainless Steel Crown
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- NuSmile, Ltd.
Appearance of Facial Wrinkles, Aesthetic
Evaluation of a Non-cross-linked Hyaluronic Acid Medical Device ("Electri" and "XELA REDERM") for Improving Facial Skin Appearance
The goal of this clinical investigation is to learn whether injectable implants based on non-cross-linked hyaluronic acid (Electri and XELA REDERM) improve the aesthetic appearance of facial skin in adult women.
- Conditions
- Appearance of Facial Wrinkles, Aesthetic, Hydration, Facial Skin Wrinkles
- Trial name
- RegHyal-01 (NCT06984432)
- Testing
- XELA REDERM (non-cross-linked hyaluronic acid 1.1%, 1.8%, or 2.2%), Electri (non-cross-linked hyaluronic acid 0.55%)
- Where
- 4 sites in Poland, Ukraine
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Institute Hyalual GmbH
Post Procedural Erythema
Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures
Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.
- Trial name
- NCT06477172
- Where
- 42 sites in United States, Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Acorn Biolabs Inc.
Nasolabial Folds
Safety and Effectiveness of Sculptra Aesthetic for Correction of Nasolabial Folds.
This study has been designed to evaluate the safety of Sculptra Aesthetic as a single regimen for correction of Nasolabial Fold (NLF) contour deficiencies after changes in reconstitution and injection procedures compared to the…
- Trial name
- NCT03780244
- Testing
- Sculptra Aesthetic 8ml, Sculptra Aesthetic 5ml
- Where
- 5 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Aging
Subjects' Satisfaction on Pan Facial Aesthetic Enhancement After Treatment With Azzalure® and the Restylane® Range
The aim of this study is to assess subjects' satisfaction linked to the pan facial management of rejuvenation with injections of Azzalure® and Restylane® fillers. This will be an open, multi-centre study.
- Trial name
- FIRST (NCT01529203)
- Testing
- Botulinum Toxin Type A (Azzalure), Restylane ranges
- Where
- 5 sites in France, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Galderma R&D
Dental Implants
Five Year Survival Study Evaluating the Genesis Dental Implant System
The purpose of this research study is to document the use if the Keystone Dental Genesis Dental Implant System in standard clinical use and to provide 5 year survival data.
- Trial name
- Genesis Dental (NCT01573026)
- Where
- 8 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Keystone Dental, Inc.
Hirsutism, Hypertrichosis
Enhanced Safety Aesthetic Laser System
The purpose of this study is to determine whether a new laser system provides better safety and efficacy than existing lasers in popular cosmetic procedures such as hair removal, treatment of cosmetically disturbing vascular…
- Conditions
- Hirsutism, Hypertrichosis, Telangiectases, Rhytides
- Trial name
- NCT00495443
- Testing
- Peterio
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Scilex Ltd.
Aesthetic Dermatology
Safety and Effectiveness Clinical Evaluation of Injectable Medical Devices Viscol
Evaluation of safety and performance of HA based injectable device for skin quality improvement
- Trial name
- NCT06142643
- Testing
- Dermal Filler Device
- Where
- Switzerland
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kylane Laboratoires
Perioral Lines
A Study to Assess Adverse Events and Effectiveness of Intradermally Injected JUVÉDERM® VOLITE™ Gel Filler in Adult Participants in China With Fine Lines Around the Mouth
Facial fine lines and wrinkles are caused by skin thinning, loss of moisture, and loss of elasticity due to factors such as age, ultraviolet (UV) radiation, and environmental exposures.
- Trial name
- NCT05454033
- Testing
- JUVÉDERM® VOLITE™, Control
- Where
- 11 sites in China
- Volunteers
- 198 people
- Sponsor
- AbbVie
Facial Subcutaneous Fullness, Subcutaneous Fat Accumulation
Efficacy and Safety of High-Dose Oral 35 kDa Hyaluronan for Aesthetic Improvement
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of high-dose oral 70 kDa hyaluronan (HA35) for aesthetic improvement.
- Conditions
- Facial Subcutaneous Fullness, Subcutaneous Fat Accumulation, Facial Inflammatory Erythema, Dull Skin
- Trial name
- HA35-ORAL (NCT07583108)
- Testing
- High-Dose Oral 35 kDa Hyaluronan (HA35)
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nakhia Impex LLC
Volume Deficiency in the Mid-Face, Aging
Study of a Novel Hyaluronic Acid Based Gel for Volume Deficiency in the Mid-face (FaceHyal)
The primary objective of the study is to demonstrate the superiority of IPN-21-SENSE versus no treatment at 24 weeks after baseline for the creation or restoration of volume deficit in the mid-face.
- Conditions
- Volume Deficiency in the Mid-Face, Aging, Aesthetics
- Trial name
- FaceHyal (NCT05747456)
- Testing
- IPN-21-SENSE
- Where
- France
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Abdominoplasty, Medical Aesthetics
Histology of SMA-001 in the Abdomen
Silk Medical Aesthetics' Inc. device, SMA-001, is currently under development as a dermal filler to fill wrinkles and folds. This study is designed to collect short-term visual, photographic, and histological and safety data on…
- Trial name
- NCT04085822
- Testing
- SMA-001
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Silk Medical Aesthetics, Inc.
Healthy
Safety and Efficacy of Topical Cream for Post-inflammatory Hyperpigmentation Skin Among Malaysians
This study was conducted to determine safety and efficacy of topically applied cream containing combination of niacinamide, arbutin, Scutellaria Baicalensis Root Extract, Centella Asiatica Extract and Camellia Sinensis Leaf…
- Trial name
- NCT05986123
- Testing
- Topical cream Z for PIH
- Where
- Malaysia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- USMARI Research & Innovation Centre
Skin Wrinkling
Autologous Platelet Rich Plasma Combined to Hyaluronic Acid Obtained With Regen-Kit BCT-HA in Aesthetic Medicine
The aim of this prospective study is to assess the efficacy of autologous Platelet Rich Plasma combined with Hyaluronic Acid prepared with RegenKit-BCT HA Cellular Matrix on skin rejuvenation.
- Trial name
- NCT02832583
- Testing
- Regenkit BCT-HA Cellular Matrix
- Volunteers
- 31 people
- Sponsor
- Regen Lab SA
Cellulite Reduction, Circumference Reduction
Clinical Study to Evaluate the Safety and Efficacy of the Vela100
This study is intended to test the safety of the Vela100 device when used for treatment for cellulite and circumference temporary reduction.
- Trial name
- NCT01026441
- Testing
- Vela100 (Aesthetic)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Physiologic Venous Dilation, Air Travel
Prospective Comparative Cohort Study of Premium Versus Economy Cabin Travel and Popliteal Vein Diameter After Long-Haul Flight After an Aesthetic Surgery
This prospective cohort study will compare popliteal vein diameter changes in international travelers who independently fly to Bogota in premium business/first class or economy class.
- Trial name
- NCT07810179
- Testing
- Premium Cabin Air Travel Exposure, Economy Cabin Air Travel Exposure, Standardized Bilateral Popliteal Vein Ultrasound
- Where
- Colombia
- Volunteers
- 200 people
- Sponsor
- Research Inc
Analgesia
Efficacy and Safety of Lidocaine and Tetracaine Cream for Facial Laser Aesthetics in Chinese Adults
Lattice laser is a new medical cosmetic technology, which is a kind of noninvasive and invasive technology. Compared with traditional laser therapy, lattice laser has a wider range of clinical use, and can be used to treat skin…
- Trial name
- NCT05793892
- Testing
- Lidocaine tetracaine cream
- Where
- 11 sites in China
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Cutia Therapeutics（Wuxi）Co.,Ltd
Physiologic Venous Dilation, Air Travel
Randomized Assessor-Masked Trial of Moderate Graduated Compression Stockings for Popliteal Vein Dilation During Long-Haul Economy-Class Air Travel After Aesthetic Surgery
This randomized assessor-masked trial will evaluate whether knee-high moderate graduated compression stockings reduce popliteal vein dilation during long-haul economy-class air travel to Bogota.
- Trial name
- NCT07810192
- Testing
- Enoxaparine, Knee-High Graduated Compression Stockings, Standardized Bilateral Popliteal Vein Ultrasound
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Research Inc