Clinical trials: Affective Disorder
Bipolar Disorder
Mental Time Travel and Identity in Bipolar Disorder Patients
Self-defining memories (SDMs) are memories that are still important today to understand who the investigators are and participate to the maintain of personal identity.
- Trial name
- NCT02793518
- Testing
- psychological tests
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Severe Acute Malnutrition, Cognitive Impairment
Intervening to Repair Cognitive and Behavioural Problems in Adults Exposed to Childhood Malnutrition
Globally, in 2011, 52 million children under 5 years old suffered from acute malnutrition, and a further 165 million children showed evidence of chronic undernutrition or stunting.
- Conditions
- Severe Acute Malnutrition, Cognitive Impairment, Emotional Disturbances
- Trial name
- NCT04053218
- Testing
- Exercise plus omega-3 supplement
- Where
- Jamaica
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Major Depressive Disorder, Depression Disorders
Near-infrared Transcranial Laser Therapy in Subjects With Major Depressive Disorder: A Study of Dosing With Laser
Note: This registration is retained as a historical study record. Updated study information and subsequent protocol modifications are available under ClinicalTrials.gov Identifier NCT06934135, which serves as the actively…
- Trial name
- NCT05435820
- Testing
- Near-infrared Transcranial Laser Therapy
- Where
- 3 sites in Peru
- Volunteers
- 50 people
- Sponsor
- Peruvian Clinical Research
Major Depressive Disorder
Impact of Psychomotor Therapy on the Quality of Life in Depression
The effectiveness of psychomotor therapy in improving clinical outcomes or quality of life for individuals with depression is unclear.
- Trial name
- PsyMot-Dep (NCT06234176)
- Testing
- Personalised psychomotor therapy, Usual treatment
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Esquirol
Moderate Depression, Clinical Depression
Task Sharing Counseling Intervention by Community Health Workers for Prenatal Depression in South Africa
The objective of this randomised controlled trial (RCT) is to determine the effectiveness and cost-effectiveness of a task sharing counseling intervention for maternal depression in South Africa(i.e.
- Conditions
- Moderate Depression, Clinical Depression, Postpartum Depression
- Trial name
- AFFIRM-SA (NCT01977326)
- Testing
- basic counselling by lay-health workers, Enhanced usual care
- Where
- 2 sites in South Africa
- Volunteers
- 4,205 people
- Sponsor
- University of Cape Town
Bipolar Disorder, Major Depressive Disorder
Sleep Quality, Cognitive Performance, and Computerized Cognitive Training
Poor sleep quality is common in neuropsychiatric conditions and some of the problems associated with poor sleep at night may be due to medication side effects or reduced efficacy of certain treatments.
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Psychosis
- Trial name
- NCT06328140
- Testing
- Lurasidone, FDA Approved antidepressant treatment
- Where
- United States
- Sponsor
- George West Mental Health Foundation d/b/a Skyland Trail
Unipolar Depression
RCT of Psychoeducational Program of Depression
The purpose of the study is to test the efficacy of a psychoeducational group program on unipolar depression
- Trial name
- NCT00319540
- Testing
- Control with depression course (CWD)
- Where
- Norway
- Volunteers
- 155 people
- Sponsor
- Norwegian Institute of Public Health
Depression
Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers
This study will aim to prevent postpartum depression in pregnant teenagers through an interpersonal therapy-based program.
- Trial name
- NCT00436150
- Testing
- Interpersonal therapy-based treatment, Standard care
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Bipolar Disorder
Using Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Bipolar Depression
The purpose of this study is to evaluate whether repetitive transcranial magnetic stimulation (rTMS) treatment is an effective adjunct treatment to mood stabilizers and Bupropion.
- Trial name
- NCT01583023
- Testing
- Bupropion, Active Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Bipolar Disorder
Olanzapine Versus Comparator in the Treatment of Bipolar Disorder
The purpose of this trial is compare the efficacy of olanzapine and Lithium Carbonate in the treatment of bipolar disorder, manic or mixed episodes, in Chinese patients.
- Trial name
- NCT00485680
- Testing
- Olanzapine Hydrochloride, Lithium Carbonate
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Eli Lilly and Company
Major Depressive Disorder, Psychedelic Experiences
Antidepressant Response of DMT Masked With Propofol
The aim of this study is to elucidate if the anti-depressive effect of N,N-dimethyltryptamine (DMT) is based on a biological mechanisms including neuroplasticity and anti-inflammatory effect or due to the subjective psychedelic…
- Trial name
- DMT4D (NCT06927076)
- Testing
- N,N-Dimethyltryptamine, Propofol, no sedation
- Where
- Switzerland
- Volunteers
- 112 people
- Sponsor
- University Hospital, Basel, Switzerland
Mental Health, Mindfulness
Perspective on Thoughts and Feelings as a Predictor of Psychological Well-being in Daily Life, in a Community Sample
This project examines the psychological construct of decentering - a mindfulness-related construct marked by an observer perspective on one's ongoing mental processes.
- Trial name
- NCT03336710
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Depressive Disorder, Major
Study Of The Effects Of A New Antidepressant Therapy In Patients With Major Depressive Disorder (MDD)
The purpose of this study is to assess the efficacy, safety and tolerability of GW679769 patients with Major depressive Disorder (MDD).
- Trial name
- NCT00413023
- Testing
- GW679769
- Where
- 39 sites in Argentina, Belgium and 9 more
- Volunteers
- 348 people
- Sponsor
- GlaxoSmithKline
Major Depressive Disorder
Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Major Depressive Disorder
The purpose of this study is to evaluate the efficacy, safety, and tolerability of Levomilnacipran ER versus placebo in the treatment of outpatients with major depressive disorder
- Trial name
- NCT01034462
- Testing
- Levomilnacipran ER
- Where
- 23 sites in United States
- Volunteers
- 442 people
- Sponsor
- Forest Laboratories
Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant
NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
Most clinical major depression responds to standard treatments (medication and psychotherapy); however, a significant subset of depressed patients (15-20%) do not respond to these treatments and are referred to as…
- Trial name
- NCT02994433
- Testing
- Nitrous Oxide, MRI
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Psychosis, Schizophrenia
Enhanced Coordinated Specialty Care for Early Psychosis
The goal of this clinical trial is to compare engagement in treatment in coordinated specialty care (CSC) to five extra care elements (CSC 2.0) in first-episode psychosis.
- Conditions
- Psychosis, Schizophrenia, Schizoaffective Disorder, Psychosis Nos/Other
- Trial name
- NCT06071858
- Testing
- Care Coordination, Individual Peer Support, Digital Outreach
- Where
- 5 sites in United States
- Volunteers
- 350 people
- Sponsor
- Mclean Hospital
Depression, Postpartum Depression
Cognitive-Behavioral Therapy (CBT) in Women Discontinuing Antidepressant for Pregnancy
The overarching goal of this study is to adapt a cognitive behavioral prevention of recurrence treatment (CBT-PR) for women with a history of recurrent major depressive disorder who decide to discontinue their maintenance…
- Conditions
- Depression, Postpartum Depression, Antenatal Depression
- Trial name
- NCT01453114
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder (MDD)
Non-invasive Brain Stimulation in Subjects with Major Depressive Disorder
Introduction The study involves the recruitment of outpatients suffering from Major Depressive Disorder (MDD), diagnosed according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5).
- Trial name
- NIBS_tDCS (NCT06714643)
- Testing
- Active tDCS
- Volunteers
- 105 people
- Sponsor
- Carmen Concerto
Major Depressive Disorder (MDD)
Study Of Bupropion SR (323U66) In Patients With Major Depressive Disorder In Japan
This is a study to obtain clinical experience of 323U66 SR for elderly patients with depression in repeat-dose of 323U66 SR up to 300mg/day, and to conduct exploratory investigation on safety, efficacy and pharmacokinetics…
- Trial name
- NCT00330616
- Testing
- 323U66 SR
- Where
- 9 sites in Japan
- Volunteers
- 35 people
- Sponsor
- GlaxoSmithKline
Major Depressive Disorder
Study Evaluating DVS-233 in Adult Outpatients With Major Depressive Disorder
Primary: To compare the antidepressant efficacy and safety of subjects receiving DVS-233 SR versus subjects receiving placebo. Secondary: To assess the response of subjects receiving DVS-233 SR for the clinical global evaluation…
- Trial name
- NCT00063206
- Testing
- DVS-233 SR
- Volunteers
- 247 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
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