Clinical trials: Affective Disorder
Sexual Behavior, Sexually Transmitted Disease (STD)
Cultural Adaptation, Validation, and Evaluation of the Programme for Promotion of Healthy Affective-Sexual Behaviours in Adolescents (IYG)
The investigators are writing to inform participants about a study being carried out by a research group from the University of Granada and the University of Seville, in which the participant's son/daughter is invited to…
- Conditions
- Sexual Behavior, Sexually Transmitted Disease (STD), Condom Use, Adolescent Health
- Trial name
- IYG (NCT07208045)
- Testing
- Es tu juego: decide bien (IYG)
- Where
- Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Seville
Mood Disorders, Schizophrenia Disorders
Psychiatric Disorders in Child and Adolescent Offspring of Parents with Schizophrenia and Bipolar Disorders.
Offspring of parents with bipolar disorder (BD) and schizophrenia (SZ) are vulnerable and at high risk for these disorders. Despite the fact that positive family history of SZ or BD is the strongest predictor for the development…
- Trial name
- NCT06874075
- Volunteers
- 50 people
- Sponsor
- Assiut University
Bipolar Disorder
Brain Small Chain Fatty Acid Metabolism in Bipolar Disorder: Ketones
Small exploratory open-label pilot study to assess supplementation of a ketone ester (Juvenescence) combined with a 'ketogenic-mimicking diet' as a potential therapy for persons with bipolar disorder.
- Trial name
- BIPO (NCT06335875)
- Testing
- Ketone Ester Beverage, Low Glycemic Index Diet
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Moderate Depression, Major Depressive Disorder
pBFS Guided 20min Inter-session Interval rTMS Treatment for MDD
The investigators aim to explore the efficacy and safety of rTMS therapies with different intervals between sessions for treating patients with moderate to severe depression.
- Conditions
- Moderate Depression, Major Depressive Disorder, Severe Depression
- Trial name
- NCT05957341
- Testing
- active rTMS: 20min inter-session interval, active rTMS: 50min inter-session interval
- Volunteers
- 50 people
- Sponsor
- Changping Laboratory
Schizophrenia, Schizo Affective Disorder
The Efficacy of Neural Stimulation in Individuals With Schizophrenia
The purpose of this study is to understand the relationship between psychotic symptoms and social functioning in individuals with schizophrenia spectrum disorders.
- Trial name
- NCT05746494
- Testing
- tDCS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas at Dallas
Treatment Resistant Depression, Transcranial Magnetic Stimulation
rTMS Intervention on Motivational Anhedonia of Treatment Resistant Depression and Brian Network Mechanism
Study of individualized accurate targeting rTMS intervention on motivational anhedonia of treatment resistant depression and brain network mechanism
- Conditions
- Treatment Resistant Depression, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging, Event-Related Potentials
- Trial name
- rTMS (NCT03991572)
- Testing
- repeated transcranial magnetic stimulation with real coil
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Depression
Omacor for Perimenopausal Depression
Recently, antidepressants and other similar acting agents have been explored as a class of medications to treat major depressive disorder (MDD) in the context of perimenopause, as well as the somatic symptoms of perimenopause…
- Trial name
- NCT00517972
- Testing
- Omacor (omega-3-acid ethyl esters)
- Where
- United States
- Sponsor
- University of Arizona
Premenstrual Disorder
Kinesio Taping vs Tele-Pilates for PMS
Premenstrual Syndrome (PMS) has a wide variety of signs and symptoms, including physical, psychological, and behavioral symptoms severe enough to disrupt daily activities.
- Trial name
- premensterual (NCT07063472)
- Testing
- Tele- pilates, Kinesio taping application for the KT group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Bipolar Disorder, Mania
Treatment of Bipolar Mania in Older Adults
This study will compare the benefits and side effects of lithium and divalproex in the treatment of older adults with bipolar mania.
- Trial name
- GERI-BD (NCT00254488)
- Testing
- Lithium (LI), Divalproex (DV)
- Where
- 8 sites in United States, Canada
- Volunteers
- 224 people
- Sponsor
- Weill Medical College of Cornell University
Postpartum Depression
Postpartum Depression and Cesarean Section
The purpose of this retrospective study is to determine if there is an increase in postpartum depression (PPD) among women who undergo an emergency cesarean section as opposed to a planned cesarean section.
- Trial name
- NCT00370903
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Depressive Disorder
Depressed Mood Improvement Through Nicotine Dosing 3
Deficits in cognitive control are core features of late-life depression (LLD), contributing both to emotion dysregulation and problems with inhibiting irrelevant information, conflict detection, and working memory.
- Trial name
- DepMIND3 (NCT05746273)
- Testing
- Transdermal Nicotine Patch
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Major Depressive Disorder, Treatment Resistant Depression
Maintenance rTMS for Depression (Maitr-De)
Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising intervention for treatment-resistant depression (TRD), yet substantial uncertainties persist regarding its efficacy as a maintenance treatment.
- Trial name
- Maitr-De (NCT06938841)
- Testing
- Transcranial Magnetic Stimulation (TMS) - Standard maintenance rTMS:, Transcranial Magnetic Stimulation (TMS) - Clustered maintenance rTMS:
- Where
- 3 sites in United States, Australia
- Volunteers
- 75 people
- Sponsor
- University of California, San Diego
Suicidal Ideation, Major Depressive Disorder
Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy
This protocol proposes an initial randomized clinical trial that includes all patients with suicidal ideation (SI) at baseline, and with SI as the primary outcome measure to examine whether Right Unilateral Low-Amplitude Pulse …
- Conditions
- Suicidal Ideation, Major Depressive Disorder, Schizo Affective Disorder, Bipolar Disorder
- Trial name
- LAP-ST vs ECT (NCT06529029)
- Testing
- Sigma-Stim, RUL LAP-ST (Low-Amplitude Pulse Seizure Therapy - Right Unilateral)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michigan State University
Bipolar Depression
Cyclooxygenase-2-Inhibitor Combination Treatment for Bipolar Depression
This project will attempt to enhance and augment the antidepressant efficacy of a commonly used antidepressant in poorly responding bipolar depressed patients.
- Trial name
- NCT01479829
- Testing
- Escitalopram, Celecoxib
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Loyola University
Dyspepsia
Effect of Genetic Association With Functional Dyspepsia and Mood Disorders
Background: Functional dyspepsia (FD) is one of the commonest digestive disorders. The pathophysiology of functional dyspepsia is uncertain. Risk factors include genetics, gender, age, helicobacter pylori infection, etc.
- Trial name
- FDFDR (NCT02282995)
- Where
- Hong Kong
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mental Health Issue, Anxiety Disorders
Arts-based Social Prescribing for Mental Health
This is a parallel-group randomised-controlled trial aiming to assess the effect of exposure to the arts on mental health and wellbeing of community dwelling recipients of mental health care.
- Conditions
- Mental Health Issue, Anxiety Disorders, Affective Disorders, Affective Disorders, Psychotic
- Trial name
- AoP-II (NCT07137572)
- Testing
- Art Prescription
- Where
- Greece
- Volunteers
- 541 people
- Sponsor
- KAVADIA ELENI
Major Depressive Disorder
Feasibility Pilot of Accelerated Stimulation With TMS for Treatment of Major Depressive Disorder (FAST-MDD)
This is a mixed-methods study that includes three steps. The first is a focus group to collect opinions and feedback about implementation of aTMS among clinicians, technicians, nurses, and other clinical staff at the St.
- Trial name
- NCT06961851
- Testing
- aTMS utilizing the MagVenture TMS device
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Depression, Depressive Disorder
Research Evaluating the Value of Augmenting Medication With Psychotherapy
This 24-week study, with a 12-month follow up period, will compare the effectiveness of antidepressant medication alone to the combination of psychotherapy and antidepressant medication in patients with chronic depression.
- Trial name
- REVAMP (NCT00057551)
- Testing
- Brief Supportive Psychotherapy, CBASP, Medication Only
- Where
- 8 sites in United States
- Volunteers
- 491 people
- Sponsor
- Weill Medical College of Cornell University
Major Depressive Disorder
A Study to Evaluate BMS-986511 in Adults With Major Depressive Disorder
A Study to Evaluate BMS-986511 in Adults with Major Depressive Disorder
- Trial name
- NCT07772531
- Testing
- BMS-986511
- Where
- 27 sites in United States, Czechia
- Volunteers
- 200 people
- Sponsor
- Bristol-Myers Squibb
Mood Disorder, Neurobehavioral Manifestation
Adolescence, Puberty, and Emotion Regulation
The purpose of this study is to use brain imaging technology to compare how the brains of adolescents and adults are activated during tasks that involve emotional responses.
- Conditions
- Mood Disorder, Neurobehavioral Manifestation, Healthy
- Trial name
- NCT00016731
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Mental Health (NIMH)
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