Clinical trials: African Americans
Increased Breastfeeding
Texting to Promote Breastfeeding (TOPS)
The purpose of the study is to see if a program of text messages that support and promote breastfeeding for expecting and delivered African-American/Black women (called TEAM2BF), as compared to a national maternal health texting…
- Trial name
- NCT06375655
- Testing
- Team2BF, Bright By Text
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Depression
Preventing Depression in the Children of Depressed African American Mothers
The purpose of the study is to adapt and test the Preventive Intervention Project for urban African American mothers with depression and their children.
- Trial name
- NCT00904917
- Testing
- Prevention Intervention Project, Psychoeducation
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma
Best African American Response to Asthma Drugs
The purpose of this study is to find the best asthma treatment to add for Blacks who have asthma that is not well controlled on a low dose of inhaled steroid.
- Trial name
- BARD (NCT01967173)
- Testing
- Flovent Diskus® 100 mcg, Flovent Diskus® 250 mcg, Flovent Diskus® 500 mcg
- Where
- 28 sites in United States
- Volunteers
- 574 people
- Sponsor
- Milton S. Hershey Medical Center
Colorectal Neoplasms
Internet-Based Motivational Interviewing for Colonoscopy
Compared to other racial groups, African Americans have the highest colorectal cancer (CRC) morbidity and mortality rates. Although colonoscopies can prevent CRC, nearly one third of African Americans have not received a…
- Trial name
- NCT03595904
- Testing
- E-Motivate group, Usual Care Group
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Asthma
physicAl aCtiviTy In minOrity womeN With Asthma Intervention
The ACTION intervention: physicAl aCtiviTy In minOrity womeN with asthma is a 3lifestyle physical activity intervention refined to be applicable for sedentary African American (AA) women with asthma.
- Trial name
- ACTION (NCT03265665)
- Testing
- ACTION Intervention, Enhanced usual care
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Illinois Chicago
HIV
Improving HIV Outcomes Among African American Transgender Women
The investigators will conduct a randomized controlled trial to test the efficacy of the mobile HIV behavioral intervention for African American transgender women (Shine).
- Trial name
- NCT05483686
- Testing
- Shine, Control
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- ISA Associates, Inc.
HIV Infections, Sexually Transmitted Diseases
Efficacy of an Abstinence-Only HIV Risk-Reduction Intervention for Young African-American Adolescents
This study will develop and evaluate the effectiveness of culturally appropriate HIV/sexually transmitted disease risk-reduction interventions in reducing sexual risk behavior among young African-American adolescents.
- Trial name
- NCT00640653
- Testing
- Abstinence-only HIV/STD risk-reduction intervention, Safer-sex-only HIV/STD risk-reduction intervention, Long comprehensive HIV/STD risk-reduction intervention
- Where
- United States
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Vaccination
Girls OnGuard: HPV Vaccination Uptake Among African American Adolescent Females
African American adolescent females seeking treatment for STIs are an underserved population at increased risk for HPV infection. While GARDASIL is an effective preventive vaccine, vaccination rates are low.
- Trial name
- Girls OnGuard (NCT00813319)
- Testing
- Girls OnGuard
- Where
- 2 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Emory University
Hypertension
Efficacy and Safety of Aliskiren Administered in Combination With Amlodipine Versus Amlodipine Alone in African American Patients With Stage 2 Hypertension
The purpose of the study is to evaluate the BP-lowering efficacy of the combination of aliskiren and amlodipine, as initial therapy, compared to amlodipine monotherapy in African American patients with Stage II hypertension.
- Trial name
- AACESS (NCT00853957)
- Testing
- Aliskiren/Amlodipine, Amlodipine
- Where
- 9 sites in United States
- Volunteers
- 443 people
- Sponsor
- Novartis
HIV
Barbershop Talk: HIV Prevention for African American Heterosexual Men
This program utilizes a community-engaged research approach to implementing and evaluating a program that seeks to reduce sexual risk behavior among Black adult heterosexual men.
- Trial name
- NCT01980771
- Testing
- BTWB intervention, Cancer prevention and screening
- Where
- 2 sites in United States
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- State University of New York - Downstate Medical Center
Transplants and Implants
Myfortic or CellCept Gastrointestinal Effects in African American Kidney Recipients
Myfortic (enteric-coated mycophenolate sodium) has been shown to have similar effectiveness to CellCept (mycophenolate mofetil) in preventing rejection in kidney transplant recipients.
- Trial name
- NCT00522548
- Testing
- Enteric coated mycophenolate sodium, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Pennsylvania
Hospice, Caregivers
A Telenovela Intervention for Caregivers of African-American and Hispanic Hospice Patients
This randomized clinical trial (RCT) intends to look at the preliminary efficacy of NOVELA (intervention group) in changing anxiety and self-efficacy compared to usual hospice care (control group).
- Trial name
- NOVELA (NCT06835764)
- Testing
- NOVELA
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Johns Hopkins University
Cardiovascular Diseases, Cognitive Decline
Brain Healthy Soul Food Diet Intervention Among Older African Americans
The primary goal of this project is to evaluate feasibility and acceptability of the MIND+SOUL diet and its implementation. Secondary goals of this project are to evaluate cardiovascular risk profile, nutritional health status…
- Trial name
- MIND+SOUL Diet (NCT05414682)
- Testing
- MIND+SOUL Diet
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Hypertension
Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study
The purpose of this study is to test the effect of oral melatonin supplementation (24 mg per night for 4 weeks) on nighttime blood pressure in African Americans with a history of elevated nighttime blood pressure.
- Trial name
- NCT01114373
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University
Peer Support and Chronic Disease, Obesity
Peer Support Dyads in Churches
The purpose of this study is to explore how working with a partner can influence participation in a church wellness program. There are many different types of church wellness programs.
- Conditions
- Peer Support and Chronic Disease, Obesity, Type II Diabetes, Cardiovascular Disease
- Trial name
- NCT03463941
- Testing
- Peer Support Dyad Intervention
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duke University
Prostate Cancer
Apalutamide and Abiraterone Acetate in African American and Caucasian Men With Metastatic Castrate Resistant Prostate Cancer
The primary goal is to prospectively estimate the median PFS of African American and Caucasian men with mCRPC taking apalutamide, abiraterone acetate, and prednisone.
- Trial name
- PANTHER (NCT03098836)
- Testing
- ARN-509, Abiraterone Acetate, Prednisone
- Where
- 14 sites in United States
- Volunteers
- 93 people
- Sponsor
- Daniel George, MD
Alzheimer Disease, Dementia
Faith-Based Toolbox for African Americans With Dementia
The purpose of this study is to create and test faith-based activities that might be useful for African American adults with moderate and severe dementia and their caregivers.
- Trial name
- NCT04325204
- Testing
- Faith-based Home Activity Toolbox (Faith-HAT)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Emory University
Patient Participation, Pediatric ALL
Inclusion Appeal Videos and Intent to Register for Pediatric Clinical Trials
An informational video about joining a Research Notification Registry is being compared with a version of the video tailored to African/ African American parents, reminding them about the importance of their being included in…
- Trial name
- NCT06138145
- Testing
- Video, Survey
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cancer, Patient Empowerment
Cancer Leadership Training for Clergy Wives and Widows
Multiple cancer health disparities exist for underrepresented minority groups, such as higher late stage diagnoses and greater cancer-related deaths.
- Trial name
- NCT04544241
- Testing
- Cancer Survivorship Leadership Training for Clergy Wives and Widows
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Systemic Lupus Erythematosus
Efficacy and Safety of Belimumab in Black Race Patients With Systemic Lupus Erythematosus (SLE)
The purpose of this study is to evaluate the efficacy, safety, and tolerability of belimumab in adult patients of black race with systemic lupus erythematosus (SLE; lupus).
- Trial name
- EMBRACE (NCT01632241)
- Testing
- Belimumab 10 mg/kg plus standard therapy, Standard therapy
- Where
- 96 sites in United States, Brazil and 4 more
- Volunteers
- 503 people
- Sponsor
- Human Genome Sciences Inc., a GSK Company