Clinical trials: Age Related Cataract
Cataract Senile
Study to Optimize the IOL Constant of a New Multifocal Intraocular Lens
Prospective, non-comparative, multicenter study on medical device with 6 months follow-up.
- Trial name
- HECATE A (NCT05201027)
- Testing
- trifocal intraocular lens
- Where
- El Salvador
- Volunteers
- 52 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Taurine Eye Drops May Prevent the Progression of Cataract
The aim of the current intervention study is to determine the effectiveness of taurine containing eye drops (available under brand name VIZILOTON) to prevent the progression of grade I and II senile cataract.
- Trial name
- NCT06639711
- Testing
- Taurine
- Where
- Iraq
- Volunteers
- 50 people
- Sponsor
- University Of Anbar
Age-Related Macular Degeneration
Five-year Incidence of Age-related Macular Degeneration in the Central Region of Portugal
To assess the five-year incidence of AMD in a population from the central region of Portugal, previously phenotypically characterized.
- Trial name
- AMDIncidencePT (NCT02748824)
- Where
- Portugal
- Volunteers
- 5,996 people, healthy volunteers welcome
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Cataract, Age-Related
Comparison of Optical Quality With Different Placement of Refractive Multifocal Intraocular Lens
The study aims to compare postoperative optical quality between two different implanting position of a rotationally asymmetric MIOL [SBL-3 Lenstec; +3.00 diopters (D)], angle kappa based implantation and 0 to 180 degree…
- Trial name
- NCT03674840
- Testing
- angle kappa based SBL-3 implantation, 0 to 180 degree SBL-3 implantation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Age Related Cataracts
The Safety and Efficacy Study of Ethylenediaminetetraacetic Acid (EDTA) Ophthalmic Solution in Patients With Loss of Contrast Sensitivity Due to Age-Related, Low-Grade Nuclear Cataract
The study objectives were: To evaluate the efficacy of EDTA 1.3% and 2.6% ophthalmic solution (C-KAD) in improving visual function as assessed by contrast sensitivity; To evaluate the safety and tolerability of two doses of EDTA…
- Trial name
- NCT06365762
- Testing
- EDTA Ophthalmic Solution 2.6%, EDTA Ophthalmic Solution 1.3%
- Where
- 6 sites in United States
- Volunteers
- 111 people
- Sponsor
- Livionex Inc.
Cataract, Sleep
The Effect of Cataract Surgery on Sleep Quality
A cataract is a clouding of the crystalline lens inside the eye, which leads to a decrease in vision. It is the most prevalent, treatable cause of visual impairment and blindness in the world.
- Trial name
- NCT02593669
- Testing
- Phacomulsification lens removal cataract surgery with neutral Intraocular lens(IOL) implantation, Phacomulsification lens removal cataract surgery with blue-blocking Intraocular lens(IOL) implantation, Subconjunctival dexamethasone and general anesthesia
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Sun Yat-sen University
Age-related Cataract
Effectiveness of Using Interactive Consulting System to Enhance Informed Choice
To compare the performance of an interactive chatbot versus senior ophthalmologists for enhancing informed decisions made by cataract patients.
- Trial name
- NCT04246346
- Testing
- An interactive chatbot for patient decision aid, Senior ophthalmologists
- Where
- China
- Volunteers
- 660 people
- Sponsor
- Sun Yat-sen University
Senile Cataract
Phacoemulsification in Patients With Corneal Opacities
In this retrospective case series, the feasibility of performing phacoemulsification using slit illumination in eyes with corneal opacity was assessed.
- Trial name
- NCT05014269
- Testing
- Phacoemulsification in eyes with corneal opacities
- Volunteers
- 10 people
- Sponsor
- Assiut University
Cataract, Age-related Cataract
Optometric Follow-up After Cataract Surgery
This study will investigate the effectiveness of an optometric follow up of cataract surgery versus an ophthalmic surgeon follow up. It will investigate patient satisfaction,safety and cost.
- Trial name
- NCT04163926
- Testing
- Intervention Group cataract follow up, Usual Care consultant follow up
- Sponsor
- Queen's University, Belfast
Cataract, Posterior Capsule Opacification
Two Different Cataract Surgical Procedures to Prevent Posterior Capsule Opacification
In this study, the investigators introduce a new "capsule-reserved" cataract surgical procedure in which anterior lens capsule is reserved and attached onto posterior lens capsule in the purpose of preventing posterior capsule…
- Trial name
- NCT02445274
- Testing
- Anterior lens capsule was reserved
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Sun Yat-sen University
Low Vision, Age Related Macular Degeneration
Early Feasibility Study Using IOPCL MAG to Improve Near Vision in ARMD Subjects
This early feasibility study aims to improve near vision in subjects 55 years or older who have a clinical diagnosis of Age-Related Macular Degeneration.
- Trial name
- NCT04984590
- Testing
- IOPCL AMD MAG
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- OnPoint Vision Inc
Age Related Cataract, Pain Management During Cataract Surgery
Iris Vascular Area Density-Based Preoperative Pain-Risk Screening and Intervention in Second-Eye Cataract Surgery
This clinical trial aims to evaluate the effectiveness of pranoprofen or prednisolone acetate eye drops for pain management in patients undergoing second-eye surgery for age-related cataracts.
- Trial name
- NCT07291089
- Testing
- Pranoprofen eye drops, Prednisolone acetate eye drops, Sodium hyaluronate eye drops
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Cataract Senile
Anterior Chamber Illumination in Cataract Surgery for Eyes With Poor Red Reflex
With a poor red reflex, it is difficult to see the anterior capsule and continuous curvilinear capsulorhexis (CCC) margin, sometimes resulting in decentered CCC or radial tearing of the anterior capsule.
- Trial name
- NCT04220138
- Testing
- Anterior chamber illumination in cataract surgery
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- University of Alexandria
Cataract Senile
Cataract Surgery In Patients With Advanced Age
This study evaluates and compares clinical outcomes of < 85 and ≥ 85 year old patients who underwent cataract surgeries.
- Trial name
- NCT04140383
- Testing
- Cataract Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people
- Sponsor
- Sakarya University
Glaucoma, Cataract Senile
Effect of Presbyopic Correction Lens on Humphrey Visual Field Testing in Patients With Multifocal Intraocular Lens
Purpose of this study was to evaluate the effect of presbyopic correction lens on Humphrey visual field (HVF) testing in patients with 2 models of multifocal intraocular lens (MIOL) both with and without glaucoma.
- Trial name
- NCT05220007
- Testing
- Humphrey visual field testing
- Where
- Thailand
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Intraocular Pressure, Cataracts Senile
Intraocular Pressure Variation by Pneumatic Tonometer Before and After Phacoemulsification
The objective of this study is to evaluate the IOP variation before and 30 days after performing phacoemulsification through pneumatic tonometry, in addition to evaluating the factors possibly related to this variation.
- Trial name
- IPOFACO (NCT03016507)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- VER Excelência em Oftalmologia
Cataract Senile
Prospective Evaluation of an Hydrophilic Acrylic Intraocular Lens
Evaluation of the clinical safety and effectiveness of an hydrophilic acrylic intraocular lens
- Trial name
- UVEA 809 (NCT04907500)
- Testing
- Intraocular lens
- Where
- Romania
- Volunteers
- 387 people
- Sponsor
- Carl Zeiss Meditec AG
Nuclear Cataract
Dose-Ranging Study of an Ophthalamic Solution in Patients With Loss of Visual Function Due to Age-Related Nuclear Cataract
This study will evaluate the safety and efficacy of three doses of C-KAD Ophthalmic Solution in patients with loss of visual function due to age-related nuclear cataract
- Trial name
- NCT00825721
- Testing
- LiquiTears, C-KAD Ophthalmic Solution
- Where
- Nepal
- Volunteers
- 81 people
- Sponsor
- Chakshu Research, Inc.
Age-related Macular Degeneration, Cataract
Age-Related Eye Disease Study 2 (AREDS2)
Oral supplementation with the Age-Related Eye Disease Study (AREDS) formulation (antioxidant vitamins C and E, beta carotene, and zinc) has been shown to reduce the risk of progression to advanced age-related macular degeneration…
- Trial name
- AREDS2 (NCT00345176)
- Testing
- Lutein/zeaxanthin, DHA/EPA, Lutein/zeaxanthin and DHA/EPA
- Where
- 91 sites in United States
- Volunteers
- 4,203 people
- Sponsor
- National Eye Institute (NEI)
Cataract
The Pathogenesis of Human Senile Cataract
To study the pathological mechanism of cataract by genomics, transcriptomics, and proteomics.
- Trial name
- NCT03907358
- Testing
- phacoemulsification
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine