Clinical trials: Age Related Hearing Loss
Age-related Hearing Impairment 1, Personal Communication
Baltimore HEARS: Hearing Health Equity Through Accessible Research & Solutions
Age-related hearing loss is highly prevalent and hearing health care is underutilized. The primary objective of the proposed randomized controlled trial is to investigate the efficacy of a community health worker (CHW)-delivered…
- Trial name
- HEARS (NCT03442296)
- Testing
- Baltimore HEARS
- Where
- 2 sites in United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Presbycusis
Longitudinal Outcomes of Hearing Aids
Age-related hearing loss is a substantial national problem due to its high prevalence and significant psychosocial consequences.
- Trial name
- NCT04030299
- Testing
- Over-the-counter fitting
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Yu-Hsiang Wu
Aging, Age Related Hearing Loss
Cognitive Training to Improve Mobility in Middle-aged and Older Adults
The proposed study is designed to evaluate the effect of at-home executive function training on cognition and mobility in older adults with age-related hearing loss (ARHL), older adults with normal hearing, and middle-aged adults.
- Trial name
- HnW (NCT05418998)
- Testing
- Executive function (EF) training
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Hearing Loss, Age-Related, Hearing Aids
Communication Training in Hearing Aid Users
The objective of the current research project is to investigate the effectiveness of communication training in first-time hearing aid users with mild to moderate hearing loss delivered in-person in groups or individually.
- Conditions
- Hearing Loss, Age-Related, Hearing Aids, Sensorineural Hearing Loss, Speech Intelligibility
- Trial name
- NCT07798453
- Testing
- Cognitive screening, Audiological Assessment, Questionnaires
- Where
- Belgium
- Volunteers
- 57 people
- Sponsor
- University Ghent
Hearing Loss, Age-Related
Hearing for Communication and Resident Engagement
Amplification is a well-established, evidence-based front-line treatment for those with impaired communication secondary to Age Related Hearing Loss (ARHL).
- Trial name
- HearCARE (NCT04575051)
- Testing
- Consult Model, Engage Model
- Where
- United States
- Volunteers
- 684 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
HIV Seropositivity
Assessment of Age-related Hearing Loss in HIV-1 Patients
The ageing process is known to be accelerated in HIV-infected patients, compared to the general population. Normal age-related hearing loss (presbyacusia) is a frequent phenomenon, affecting more than 70% of people above 65…
- Trial name
- HELO (NCT02154971)
- Where
- France
- Volunteers
- 206 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Presbycusis, Hearing Loss, Sensorineural
FX-322 in Adults With Age-Related Sensorineural Hearing Loss
This is a Phase 1b, prospective, randomized, double-blind, placebo-controlled, single-dose, multicenter, safety study of FX-322, administered by intratympanic injection, in adults with age-related sensorineural hearing loss.
- Conditions
- Presbycusis, Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
- Trial name
- NCT04601909
- Testing
- FX-322
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Frequency Therapeutics
Age-related Hearing Loss, Cognitive Decline
Study of Cognitive Reserve Disorder Affecting Depression in Aged Related Hearing Loss Via Rest State EEG
In this study, patients with aged-related hearing loss with depression and without depression were evaluated by audiometry (pure tone audiometry and speech audiometry), cognitive function assessment (MMSE scale for simple mental…
- Conditions
- Age-related Hearing Loss, Cognitive Decline, Depression
- Trial name
- NCT05892731
- Testing
- with depression, without depression
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Central Auditory Processing Disorder, Hearing Impaired (Partially)
A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
The goal of this clinical trial is to determine the efficacy of Clemastine Fumarate in the presence of engineered sound to treat age-related central auditory processing disorder (CAPD).
- Conditions
- Central Auditory Processing Disorder, Hearing Impaired (Partially), Hearing, Hearing Abnormality
- Trial name
- CAPD-LOOT (NCT07304024)
- Testing
- Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Colorado, Denver
Presbycusis, Bilateral, Alzheimer Disease 2 Due to Apoe4 Isoform
Hearing Aid and Individuals With Cognitive Disorders
This is a pilot study with the aim of evaluating the feasibility of the procedures of a future clinical trial that will help determine the impacts of hearing aid interventions on older patients with Alzheimer's Disease and…
- Conditions
- Presbycusis, Bilateral, Alzheimer Disease 2 Due to Apoe4 Isoform, Mild Cognitive Impairment
- Trial name
- NCT04049643
- Testing
- Audiologist-based fitting, Service-only Fitting, Device-only fitting
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Yu-Hsiang Wu
Presbycusis
Improving Speech in Noise Perception for Individuals With Age-related Hearing Loss
Hearing loss, especially for speech perception in the presence of noise, may lead older individuals to withdraw from social situations.
- Trial name
- NCT07192757
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alzheimer Disease, Hearing Loss
Early Age-Related Hearing Loss Investigation (EARHLI)
Early Age-Related Hearing Loss Investigation (EARHLI) is a single site study that will randomize late middle age adults to either a hearing intervention (including hearing aids) or a health education intervention.
- Conditions
- Alzheimer Disease, Hearing Loss, Cognitive Impairment
- Trial name
- EARHLI (NCT06174038)
- Testing
- Hearing Intervention, Health Education Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Alzheimer Disease, Presbycusis
Clinical Trial on Alzheimer Disease, Presbycusis and Hearing Aids
This is a 12-months' randomized clinical trial that aims at studying the benefit of bilateral hearing aids in hearing impaired patients suffering from a slight to moderate stage Alzheimer disease.
- Trial name
- NCT00488007
- Testing
- Hearing aids used : PHONAK Savia and Valeo
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
Alzheimer Disease, Presbycusis
Age-related Hearing Loss and Lexical Disorders
In France, Alzheimer's disease accounts for 70 to 80% of the causes of neurocognitive disorders, i.e. 600,000 to 800,000 patients.
- Conditions
- Alzheimer Disease, Presbycusis, Lexical Syntactic Disorder
- Trial name
- LOOP (NCT03638323)
- Testing
- Speech therapy
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Presbycusis, Tinnitus
Effects of Huperzine a on Presbycusis(Δ,kHz, DB,MMSE, AD)
To investigate the effects of huperzine A on tinnitus suppression, hearing and cognitive function protection in patients with presbycusis-related subjective tinnitus and cognitive impairment.
- Conditions
- Presbycusis, Tinnitus, Cognitive Impairment
- Trial name
- NCT03101722
- Testing
- BTHE and Huperzine A, BETH
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhijun Bao
Hearing Loss, Bilateral Sensorineural, Progressive, Hearing Loss, Bilateral (Causes Other Than Tumors)
Hearing Screening in Adults Over 50 Years Old
The goal of this single-arm quasi-experimental study is to evaluate the feasibility, effectiveness, and management of three different hearing screening methods in adults aged 50 years and older in the Czech Republic.
- Conditions
- Hearing Loss, Bilateral Sensorineural, Progressive, Hearing Loss, Bilateral (Causes Other Than Tumors), Hearing Loss, Bilateral or Unilateral, Presbyacusis
- Trial name
- HSA50+ (NCT06894927)
- Testing
- Screening HHIA questionnaire, Whispered voice test, Screening pure tone audiometry
- Where
- 2 sites in Czechia
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University Hospital Hradec Kralove
Hearing Loss, Age-Related
Early Identification of Age-related Hearing Impairment
The need for future hearing rehabilitation is enormous. World Health Organization (WHO 2021) has estimated that by 2050, 2.5 billion people will have some degree of hearing loss, and 1/4 of them will require hearing…
- Trial name
- NCT06418321
- Testing
- Investigational device, Audiometer, Otomicroscopy
- Where
- 2 sites in Finland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Aalto University
Presbycusis, Bilateral
Impact of Hearing Aid Technology on Self-reported Outcomes
The study aims to investigate if the level of hearing aid (HA) technology has an impact on self-reported outcomes in patients with presbycusis in terms of overall IOI-HA scores, Factor 1, Factor 2 scores, SSQ scores, and the SSQ…
- Trial name
- NCT04539847
- Testing
- High-end hearing aid, Basic hearing aid
- Volunteers
- 208 people
- Sponsor
- University of Southern Denmark
Age-related Hearing Loss, Dementia
Management of Age-Related Auditory Decline and Early Warning of Its Co-occurring Dementia
Against the backdrop of global population aging, age-related hearing loss (ARHL) has reached epidemic proportions and is increasingly recognized as an independent risk factor for cognitive decline and other major…
- Trial name
- AHEAD (NCT07608640)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Hearing Loss
Evaluation of Unilateral vs Bilateral Hearing Aids for the Treatment of Age-related Hearing Loss
This study aims to evaluate the benefit of bilateral hearing aid use compared to a unilateral hearing aid. Patients with mild to moderate bilateral hearing loss who are considering the purchase of a commercially available hearing…
- Trial name
- NCT04739436
- Testing
- Hearing amplification
- Where
- 2 sites in United States
- Volunteers
- 278 people
- Sponsor
- Duke University