Clinical trials: Aged, 80 and Over
Community-acquired Pneumonia, Healthcare-associated Pneumonia
Impact of a Multidimensional Intervention in Elderly Patients With Pneumonia
The hypothesis of this study is that long-term outcome in elderly patients admitted with the diagnosis of community-acquired pneumonia (CAP) or healthcare-associated pneumonia (HCAP) would improve with a multidimensional…
- Trial name
- IMIEPAP (NCT01285869)
- Testing
- Multidimensional intervention
- Where
- Spain
- Volunteers
- 314 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Accidental Falls
Multifactorial Falls Prevention Program - Brazil
This study is a clinical trial designed to evaluate the effectiveness of a multifactorial falls prevention program in reducing the rate of falls.
- Trial name
- NCT01698580
- Testing
- On-site exercise, home-based exercise, Educational and behavioural
- Where
- Brazil
- Volunteers
- 612 people
- Sponsor
- University of Sao Paulo
Aged, 80 and Over, Critical Care
Prognostic Score in the Very Old ICU Patients
The two main aims of the study: 1. To investigate the relation of Frailty, Activity of daily life (ADL), Cognitive functions and Co-morbidity on survival at 30 days (and 6 months in a substudy) 2.
- Trial name
- VIP2 (NCT03370692)
- Testing
- Cognitive assesment, Frailty assessment
- Where
- Norway
- Volunteers
- 3,900 people
- Sponsor
- University of Bergen
Atrial Fibrillation
New Oral Direct Anticoagulants in Patients 80 Years Old and Over : a Population Pharmacokinetics Study
Several new oral direct anticoagulants have been recently marketed. However, only a few, limited, studies have provided data about the pharmacology of new oral direct anticoagulants in older persons.
- Trial name
- ADAGE (NCT02464488)
- Testing
- Plasma drug concentrations
- Where
- 2 sites in France
- Volunteers
- 232 people
- Sponsor
- Hôpital Charles Foix
Neuromuscular Blockade, Intubation Complication
A Comparison of Rocuronium 0.6 mg/kg and Remifentanil 2 µg/kg in Elderly Patients Over 80 Years
The number of elderly patients above 80 years is increasing and a large proportion of these patients will require surgery and anesthesia.
- Conditions
- Neuromuscular Blockade, Intubation Complication, Anesthesia
- Trial name
- NCT04287426
- Testing
- Rocuronium 0.6 mg/kg, Remifentanil 2 µg/kg
- Where
- 2 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Musculoskeletal Pain, Musculoskeletal Pain Disorder
Exergaming Experience of Older People With Chronic Musculoskeletal Pain
Chronic musculoskeletal pain is debilitating and can lower the quality of life in older people. Therapeutic benefits have been reported from exergaming used as an intervention for rehabilitation or alternative to exercise.
- Trial name
- NCT04029285
- Testing
- Exergaming
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Teesside University
Dementia, Cognition Disorders in Old Age
Neuropsychological Assessment Of The Oldest-Old Population.(NEUROPSIC-GR)
Neuropsychological tests currently considered to evaluate the cognitive performance of the oldest-old population (more than 80 years) are not adapted to this group population.
- Trial name
- NEUROPSIC-GR (NCT05481749)
- Where
- 6 sites in Spain
- Volunteers
- 113 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Malnutrition
Effects of Nutritional Supplementation and Dietary Advice in Elderly Patients After Hospital Discharge.
The purpose of this study is to evaluate the effects of nutritional therapy in elderly malnourished patients. The hypothesises are that nutritional supplementation and dietary advice alone or in combination affects mortality…
- Trial name
- NCT01057914
- Testing
- Nutritional supplementation with a liquid formula, Dietary advice, Combination of supplement and dietary advice
- Where
- 5 sites in Sweden
- Volunteers
- 671 people
- Sponsor
- Uppsala University
Non Previously Treated CD20+ Diffuse Large B-cell Lymphoma
Study of Mini-Chop Plus Ofatumumab To Treat Cd 20+ Diffuse Large B-Cell Lymphoma In Patients Aged Over 80 Years
This study is a multicentric, phase II, open-label, non-randomized trial evaluating the efficacy of O-miniCHOP in patients aged over 80 years with non previously treated CD20+ diffuse large B-cell lymphoma (age-adjusted IPI=0…
- Trial name
- NCT01195714
- Testing
- Ofatumumab
- Where
- 84 sites in Belgium, France
- Volunteers
- 120 people
- Sponsor
- The Lymphoma Academic Research Organisation
Pressure Ulcers, Venous Ulcers
Use of Fish Skin Extracellular Matrix (ECM) to Facilitate Chronic Wound Healing
The clinical study is designed to assess the effectiveness, safety and non-immunogenicity of fish skin wound dressing extracellular matrix (ECM) in treating chronic wounds.
- Conditions
- Pressure Ulcers, Venous Ulcers, Diabetic Ulcers, Chronic Ulcer of Foot
- Trial name
- NCT01348581
- Testing
- Marigen Wound Dressing
- Where
- Iceland
- Volunteers
- 37 people
- Sponsor
- Kerecis Ltd.
Confusion, Inflammation
Confusion in the Elderly After Colon Surgery
A study will be conducted to determine if there is any cognitive benefit in elderly patients having open versus minimally invasive colon cancer surgery.
- Conditions
- Confusion, Inflammation, Acute Phase Reaction, Surgery
- Trial name
- NCT01623297
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- New York Hospital Queens
Sarcopenia, Aging
Reducing Falls With Progressive Resistance Training for the Oldest Old Adults With Reduced Muscle Strength
This study will investigate the effects of 12 months of high-intensity progressive resistance training compared with a control group on fall-rate in older adults with reduced muscle strength.
- Trial name
- ReFit (NCT05691166)
- Testing
- High-intensity progressive resistance training, Written physical activity guidance
- Where
- Norway
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Depression
Preventing the Return of Depression in Elderly Patients
The purpose of this study is to compare the effectiveness of two doses of nortriptyline in elderly patients whose depression returned after stopping treatment. Nortriptyline is an antidepressant.
- Trial name
- NCT00000377
- Testing
- Nortriptyline
- Sponsor
- University of Pittsburgh
Sedentary
Effects of Two Physical Exercise Protocols on Cognition and Physical Performances in Elderly Over 80 Years
The purpose of this study is to compare the effects of different trainings on cognition and physical performances in elderly over 80 years.
- Trial name
- NCT01983397
- Testing
- Multicomponent training, Resistance training
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Neurocognitive Disorders, Dementia
The Impact of Dementia and Neurocognitive Disorders on Hypertension Treatment in the Elderly
Neurocognitive disorders and hypertension occur commonly with aging. While, by definition, older adults are at high cardiovascular risk, there is no guideline exist currently on blood pressure management of elderly hypertension.
- Conditions
- Neurocognitive Disorders, Dementia, Hypertension, Aged, 80 and Over
- Trial name
- TAHOC (NCT05845736)
- Testing
- Antihypertensive Agents
- Where
- France
- Volunteers
- 353 people
- Sponsor
- Central Hospital, Nancy, France
Anesthesia
Oldest-old Patients Anesthesia in Orthopedic Surgeries
Average life span, life expectancy, and the number of older people, aged 65 years and over, have increased during the last decades.
- Trial name
- NCT06522178
- Testing
- Patient' ages
- Where
- Turkey (Türkiye)
- Volunteers
- 1,356 people
- Sponsor
- Istanbul Medeniyet University
Volunteers
Effects of Mode of Contraction on Neuromuscular Fatigue
Aging is associated with multiple deteriorations of the neuromuscular system. Given the increase in life expectancy, the investigators can now distinguish old adults (>60 years old) who conserve their neuromuscular capacities…
- Trial name
- DYN-AGING (NCT04516538)
- Testing
- Mini Mental State Examination, 6 Minutes Walk Test, Timed up and go
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hip Fractures, Albumin
Evaluation of Relationship Between Preoperative Fibrinogen/Albumin Ratio and Morbidity After Hip Fracture Operations
Due to the aging of populations, hip fracture operations are increasing from year to year. This operations have many complications also high morbidity and the mortality.
- Conditions
- Hip Fractures, Albumin, Fibrinogen, Scoring Systems
- Trial name
- NCT05272072
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Istanbul University
Postoperative Complication
Keratinocyte Skin Cancer Surgery in the Elderly, Aged 80 Years and Over, is Effective and Safe
As a result of a longer life expectancy and a change in UV exposure, physicians will be facing a growing number of elderly patients with keratinocyte cancer (KC) in fair-skinned populations.
- Trial name
- NCT06665581
- Where
- 2 sites in Switzerland
- Volunteers
- 345 people
- Sponsor
- Juerg Hafner
Adults, Middle Age
Effect of GEMS-H on Locomotor Function in Adults
The purpose of this study is to investigate the effect of training with the Gait Enhancing and Motivating System-Hip (GEMS-H) vs. training without the GEMS-H on locomotor function in adults.
- Conditions
- Adults, Middle Age, Aged, Aged, 80 and Over
- Trial name
- NCT03962517
- Testing
- with Gait Enhancing and Motivating System-Hip (GEMS-H), without Gait Enhancing and Motivating System-Hip (GEMS-H)
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Samsung Electronics