Clinical trials: Aged, 80 and Over
Accidental Falls
Multifactorial Falls Prevention Program - Brazil
This study is a clinical trial designed to evaluate the effectiveness of a multifactorial falls prevention program in reducing the rate of falls.
- Trial name
- NCT01698580
- Testing
- On-site exercise, home-based exercise, Educational and behavioural
- Where
- Brazil
- Volunteers
- 612 people
- Sponsor
- University of Sao Paulo
Fall, Fall Injury
A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients
Falls in older adults represents a growing public health challenge. The use of certain medication is recognized as an important modifiable risk factor for falls.
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- ADFICE_IT (NCT05449470)
- Testing
- CDSS, Patient Portal
- Where
- 10 sites in Netherlands
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Polypharmacy, Adverse Drug Reaction
Educational Intervention to Reduce Drug-related Hospitalizations in Elderly Primary Health Care Patients
The purpose of this study is to determine whether an educational intervention given towards health care providers working in primary health care centers can reduce inappropriate prescribing in the elderly patient and thus reduce…
- Trial name
- NCT01732302
- Testing
- Educational intervention
- Where
- Sweden
- Volunteers
- 69 people
- Sponsor
- Karolinska Institutet
Hip Fractures, Albumin
Evaluation of Relationship Between Preoperative Fibrinogen/Albumin Ratio and Morbidity After Hip Fracture Operations
Due to the aging of populations, hip fracture operations are increasing from year to year. This operations have many complications also high morbidity and the mortality.
- Conditions
- Hip Fractures, Albumin, Fibrinogen, Scoring Systems
- Trial name
- NCT05272072
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Istanbul University
the Health Status of the Oldest Old
Health Status of the Oldest-old Population
This study aims to investigate the health status of the oldest-old population and to explore the key factors associated with their quality of life The study will select all the elderly aged 85 years and above from Lanqiying…
- Trial name
- NCT04553874
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Peking University
Anesthesia
Oldest-old Patients Anesthesia in Orthopedic Surgeries
Average life span, life expectancy, and the number of older people, aged 65 years and over, have increased during the last decades.
- Trial name
- NCT06522178
- Testing
- Patient' ages
- Where
- Turkey (Türkiye)
- Volunteers
- 1,356 people
- Sponsor
- Istanbul Medeniyet University
Hypothyroidism
REduction of LEvothyroxine in Adults; a SElf Controlled Study
Many older persons use the thyroid hormone levothyroxine which is often continued for life. Scientifically, there is much uncertainty whether simple continuation is the optimal approach.
- Trial name
- RELEASE (NCT05821881)
- Testing
- Discontinuation of levothyroxine treatment
- Where
- Netherlands
- Volunteers
- 513 people
- Sponsor
- Leiden University Medical Center
Sarcopenia, Aging
Reducing Falls With Progressive Resistance Training for the Oldest Old Adults With Reduced Muscle Strength
This study will investigate the effects of 12 months of high-intensity progressive resistance training compared with a control group on fall-rate in older adults with reduced muscle strength.
- Trial name
- ReFit (NCT05691166)
- Testing
- High-intensity progressive resistance training, Written physical activity guidance
- Where
- Norway
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Aortic Stenosis, Coronary Ang
Coronary Artery Disease in Elderly People Referred for TAVI
The investigators prognostic impact of coronary artery disease (CAD) and of percutaneous coronary intervention (PCI) in patients with indication of TAVI is controversial, particularly in elderly population where CAD and aortic…
- Trial name
- CEPTAVI (NCT04930510)
- Where
- France
- Volunteers
- 170 people
- Sponsor
- University Hospital, Montpellier
Intensive Care Units (ICUs), Muscle Atrophy or Weakness
Neuromuscular Electrical Stimulation in Critically Ill Patients Aged 80 and Over
The aim of this clinical trial is to evaluate the effectiveness of Medium-Frequency Neuromuscular Electrical Stimulation, in combination with standard physical therapy, compared to standard physical therapy alone, on muscle mass…
- Conditions
- Intensive Care Units (ICUs), Muscle Atrophy or Weakness, Old and Very Old People
- Trial name
- NMES-ICU80 (NCT07127991)
- Testing
- Medium Frequency Neuromuscular Electrical Stimulation (NMES), Standard physical therapy
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad de La Frontera
Osteoarthritis of the Knee
Structured Non-operative Treatment of Knee Osteoarthritis
The purpose of this study is to test whether an algorithm for systematic non-surgical treatment consisting of corrective insoles, neuromuscular training, weight loss, patient education and pharmacological treatment with…
- Trial name
- NCT01535001
- Testing
- Neuromuscular training (NEMEX-TJR), Information, Paracetamol
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Aged, 80 and Over, Critical Care
Prognostic Score in the Very Old ICU Patients
The two main aims of the study: 1. To investigate the relation of Frailty, Activity of daily life (ADL), Cognitive functions and Co-morbidity on survival at 30 days (and 6 months in a substudy) 2.
- Trial name
- VIP2 (NCT03370692)
- Testing
- Cognitive assesment, Frailty assessment
- Where
- Norway
- Volunteers
- 3,900 people
- Sponsor
- University of Bergen
Depression
Preventing the Return of Depression in Elderly Patients
The purpose of this study is to compare the effectiveness of two doses of nortriptyline in elderly patients whose depression returned after stopping treatment. Nortriptyline is an antidepressant.
- Trial name
- NCT00000377
- Testing
- Nortriptyline
- Sponsor
- University of Pittsburgh
Accidental Falls
The HIP-HOP Flooring Study: Helping Injury Prevention in Hospitalised Older People
In hospitals, older people can fall and hurt themselves. The investigators want to see if a new type of flooring can help stop people hurting themselves as badly, if they accidentally fall.
- Trial name
- NCT00817869
- Testing
- New flooring
- Where
- 8 sites in United Kingdom
- Volunteers
- 571 people
- Sponsor
- University of Portsmouth
Cognition, Dementia
Computerized Cognitive Intervention in the Oldest-Old
Little is known about preventive strategies with immediate public health impact for cognitive functioning in the oldest-old (OO).
- Trial name
- NCT03397498
- Testing
- CogniFit™, Control-games
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Non Previously Treated CD20+ Diffuse Large B-cell Lymphoma
Study of Mini-Chop Plus Ofatumumab To Treat Cd 20+ Diffuse Large B-Cell Lymphoma In Patients Aged Over 80 Years
This study is a multicentric, phase II, open-label, non-randomized trial evaluating the efficacy of O-miniCHOP in patients aged over 80 years with non previously treated CD20+ diffuse large B-cell lymphoma (age-adjusted IPI=0…
- Trial name
- NCT01195714
- Testing
- Ofatumumab
- Where
- 84 sites in Belgium, France
- Volunteers
- 120 people
- Sponsor
- The Lymphoma Academic Research Organisation
Atrial Fibrillation
Benefit/Risk in Real Life of New Oral Anticoagulants and Vitamin K Antagonists in Patients Aged 80 Years and Over
The aim of the study is to compare, in real life, the risk benefit (including both major bleeding and thrombotic events (TE) and death from any cause) associated with direct oral anticoagulants (DOA) and with anti vitamin K (VKA)…
- Trial name
- PRESAGE-ACO (NCT02286414)
- Testing
- Direct oral antocoagulant: dabigatran, rivaroxaban, apixaban, Vitamin K antagonist: warfarin, fluindione, acenocoumarol
- Where
- France
- Volunteers
- 159 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris