Clinical trials: Aged
Picky Eating
PEaters Choice™: Nutrition Intervention Module for Picky Eaters
Picky eaters (PE) are defined as individuals with a lack of diversity in food intake and fear of trying new foods which generally leads to malnutrition. Globally, between 20% to 55% of children worldwide are being reported as PE.
- Trial name
- PEaters (NCT05445193)
- Testing
- PEaters Choice Module
- Where
- Malaysia
- Volunteers
- 154 people
- Sponsor
- National University of Malaysia
Evaluation of Corneal Endothelium in Elderly Diabetic Patient
Evaluation of Corneal Endothelium by Specular Microscope in Elderly Diabetic Patients
A low endothelial count with endothelial pump dysfunction can contribute to corneal stromal hydration and loss of vision that can only be reversed by corneal transplantation,so this research proposed to detect any corneal…
- Trial name
- NCT06196333
- Testing
- Non-contact specular microscopy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cannabis Use, Old Age
Health Condition of Cannabis Consumers in the Canadian Population
This study evaluates the health condition and its evolution with time of Cannabis consumers in the Canadian population.
- Conditions
- Cannabis Use, Old Age, Health Risk
- Trial name
- NCT03987347
- Testing
- Observational
- Where
- Canada
- Sponsor
- Jewish General Hospital
Polytrauma, Traumatic Brain Injury
Age, Traumatic Brain Injury and Injury Severity as Independent Risk Factors for In-Hospital Mortality in Polytrauma Patients.
In this study patients who were admitted to our hospital with critical injuries were enrolled retrospectively from January 2012 to December 2015.
- Trial name
- NCT04335838
- Testing
- retrospective analysis
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Translation, Cultural Adaptation and Turkish Validation
Translation, Cross-Cultural Adaptation and Turkish Validation of the 25-Question Geriatric Locomotive Function Scale
25-question Geriatric Locomotive Function Scale (GLFS-25) is a patient-reported outcome measure consisting of 25 questions that evaluates locomotive functions and locomotive syndrome risk in elderly individuals.
- Trial name
- NCT05214755
- Where
- Turkey (Türkiye)
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
CHILDREN BORN VERY PRETERM AT SCHOOL-AGE
QUALITY OF LIFE OF CHILDREN BORN VERY PRETERM AT SCHOOL-AGE
AIMS The aims were 1) to describe the quality of life (QoL) of a cohort of children born very preterm (<28 weeks of gestation) aged 7 to 9 years; 2) to compare children's QoL to the QoL reported by a French general population of…
- Trial name
- NCT01675726
- Testing
- questionary on quality of life
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Telemedicine, Elderly
Effectiveness of Mobile Health on Frailty, Muscle Strength and Health Literacy of the Elderly
This study explores the effect of mobile health combined with multi-course intervention on frailty, muscle strength, health literacy and nutrition knowledge among the elderly in the community.
- Conditions
- Telemedicine, Elderly, Health Literacy
- Trial name
- NCT05483478
- Testing
- mobile health combined Multi-course Program
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Landseed Hospital
Colo-rectal Cancer
Prehabilitation in Geriatric Patients With Colorectal Neoplasia
This an interventional, non-pharmacologic study. Prehabilitation is a multidisciplinary preoperative intervention aimed at preventing or reducing functional decline related to surgery and improving perioperative outcomes.
- Trial name
- PIGEON (NCT05851235)
- Testing
- Prehabilitation course
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Gastric Cancer
A Single-arm, Phase II Exploratory Study of Sintilimab in Combination With Chemoradiotherapy in Elderly Patients With Locally Advanced Gastric Cancer
This trial is a prospective, single-arm, single-centre, phase II clinical study to explore the efficacy and safety of sintilimab in combination with chemoradiation in subjects over 75 years of age with advanced gastric cancer.
- Trial name
- NCT06555471
- Testing
- Sintilimab, S-1, Capecitabine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Major Depression
Predictors of the Outcome of Late Life Depression
Predictors of response to pharmacological treatment of major depressive disorder will be investigated. One hundred and twenty patients will be included in a naturalistic clinical trial.
- Trial name
- NCT02441387
- Testing
- Antidepressant, Psychoeducation, Treatment as usual (only pharmacological treatment).
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Elevated Blood Lead Levels
Effect of Lactobacillus Plantarum DSM 33464 on Blood Lead Levels in Young Women of Child-bearing Age
We hypothesize that Lactobacillus Plantarum DSM 33464 reduce lead levels. Approximately 200 women 18 to 40 will be screened for blood lead levels.
- Trial name
- NCT05507021
- Testing
- Lactobacillus plantarum DSM 33464, MegaMetalliQ
- Where
- Mexico
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI)
CPAP Randomized Controlled Trial
The overall goal of this randomized controlled trial is to test the hypothesis that in older adults with mild cognitive impairment (MCI) and previously untreated obstructive sleep apnea (OSA), 4 months of web-based sleep…
- Conditions
- Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI), Cognitive Decline Prevention in Pre-frail Older Adults
- Trial name
- NCT06773416
- Testing
- CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health, Delayed CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health
- Where
- Canada
- Volunteers
- 206 people
- Sponsor
- Sunnybrook Health Sciences Centre
Neurocognitive Disorders
Personalized Interventions Via Health Portraits in Mild Behavioral Impairment
The incidence of MBI and the probability of progression to dementia are high. Early detection and intervention have important clinical significance to reduce the occurrence of dementia, delay the progression of dementia and…
- Trial name
- NCT06416514
- Testing
- Personalized intervention
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujian Provincial Hospital
Sleep Initiation and Maintenance Disorders
Efficacy Study of EVT 201 in the Treatment of Elderly Patients With Daytime Sleepiness
The purpose of this study is to determine whether a compound known as EVT 201 is effective in treating elderly patients diagnosed with primary insomnia who also have moderate daytime sleepiness.
- Trial name
- NCT00401284
- Testing
- EVT 201
- Where
- 22 sites in United States
- Volunteers
- 135 people
- Sponsor
- Evotec Neurosciences GmbH
Total Hip Arthroplasty, Wear
Age Dependency of Biological Reaction on Wear Particles
Wear is the main reason for revision operations after joint arthroplasty. While the survival of modern implants is often longer than the expected life span in old patients, young patients (<60 years) have to expect at least one…
- Trial name
- NCT03164733
- Testing
- incubation
- Volunteers
- 80 people
- Sponsor
- University of Jena
Neovascular Age-Related Macular Degeneration (nAMD) Wet AMD
Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration
The purpose of this study is to evaluate safety, effectiveness and durability of a gene therapy called Ixo-vec (Ixoberogene soroparvovec) when administered to the contralateral (second) eye of adult participants (≥ 50 years of…
- Trial name
- NCT07630649
- Testing
- Ixo-vec
- Where
- 12 sites in United States
- Volunteers
- 15 people
- Sponsor
- Adverum Biotechnologies, Inc.
Tuberculosis
Evaluation of the Safety and Immunogenicity of the Recombinant Subunit Vaccine "GamTBvac" Against the Tuberculosis.
The study is aimed to evaluate the safety and immunogenicity of the medicinal product "GamTBvac" - a recombinant subunit vaccine against the tuberculosis.
- Trial name
- GamTBvac (NCT03255278)
- Testing
- Single GamTBvac vaccination (0.25 dose), Double GamTBvac vaccination (0.25 dose), Double GamTBvac vaccination (0.5 dose)
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Children, Only
Occupational Therapy With Ayres Sensory Integration Approach for School-age Children
Introduction: Sensory Integration (SI) is a theory and framework conceptualized by Dr. Jean Ayres, a highly experienced occupational therapist, with its main objective as enhancing the brain's capacity to perceive and organize…
- Trial name
- NCT03596515
- Testing
- Sensory Integration
- Volunteers
- 52 people
- Sponsor
- Hospital Authority, Hong Kong
Chronic Insomnia
Insomnia Behavioral Intervention Study
This randomized pilot study (n=20) explores the effects of a behavioral intervention, that includes sleep hygiene improvements, in long-term users of sleeping pills, aiming to alleviate or stabilize symptoms of insomnia, monitor…
- Trial name
- IBI (NCT05301543)
- Testing
- Experimental: Behavioral approach 1, Comparator: Behavioral approach 2
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Clostridium Difficile Infection
Study of a Candidate Clostridium Difficile Toxoid Vaccine in Healthy Adult Subjects Aged 40 to 75 Years in Japan
The aim of the study is to evaluate a candidate C. difficile Toxoid Vaccine in the Japanese population. Primary objectives: To describe the safety profile of all subjects who receive at least 1 injection To describe the…
- Trial name
- NCT01896830
- Testing
- Clostridium difficile Toxoid Vaccine, 0.9% normal saline
- Where
- Japan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company