Clinical trials: Aged Skin
Skin Aging, Skin Wrinkling
Efficacy and Performance Evaluation of mGlobal L+AS 20 mg/ml Hyaluronic Acid, for the Correction of Light to Moderate Wrinkles and Folds
The investigation is a single-centre, interventional, prospective, non-randomized, open-label, uncontrolled, single-arm, un-blinded investigation for evaluation of the safety and performance of the product mGlobal L+AS for…
- Trial name
- M-GLO-LS (NCT06482723)
- Testing
- mGlobal L+AS
- Where
- Bulgaria
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Psoriasis
A Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis
This study was created to provide subjects who complete Week 52 (end of Apremilast Extension Phase) of study CC-10004-PPSO-003 the option to continue to receive open-label apremilast therapy.
- Trial name
- NCT04175613
- Testing
- Apremilast
- Where
- 50 sites in United States, Belgium and 7 more
- Volunteers
- 160 people
- Sponsor
- Amgen
Intrinsic Aging of Skin
Retinol on Human Skin Aging in East Asian Descent
There has been increasing evidence for different rates of natural aging in humans and one of the best organs to study human aging is skin.
- Trial name
- NCT02906566
- Testing
- Retinol
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Stanford University
Aging Skin
Hyaluronic Acid Delivery: CO2 Laser Versus Thulium Laser Treatment
Weakly crossed-linked hyaluronic acid (HA) can be delivered through multiple injections into the dermal and subnormal layer to improve skin quality. However, this treatment comes with multiple bumps for several days.
- Trial name
- NCT06431282
- Testing
- CO2 laser + HA, Thulium laser + HA
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Skin Aging
Thermage CPT for Treatment of Facial and Neck Laxity
The purpose of this study to evaluate treatment with the Thermage CPT system for facial and neck laxity.
- Trial name
- NCT01783496
- Testing
- Thermage CPT
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Valeant Pharmaceuticals
Xerosis Cutis, Dry Skin
Enhancing SKIN Health and Safety in Aged CARE
Aged long-term care receivers are affected by various adverse skin conditions like pressure ulcers, incontinence-associated dermatitis, dryness, intertrigo and many more.
- Conditions
- Xerosis Cutis, Dry Skin, Pruritus, Pressure Ulcer
- Trial name
- SKINCARE (NCT03824886)
- Testing
- Implementation of skin care algorithm
- Where
- 2 sites in Germany
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- PD Dr. Jan Kottner
Skin Aging, Facial Rhytides
AnteAGE Biosomes With Radiofrequency Microneedling for Facial Skin Rejuvenation
This prospective, randomized controlled study evaluated the efficacy and tolerability of AnteAGE Biosome Solution used in conjunction with facial radiofrequency microneedling.
- Conditions
- Skin Aging, Facial Rhytides, Skin Tone
- Trial name
- NCT07849556
- Testing
- AnteAGE Biosome Treatment Solution, Radiofrequency Microneedling, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Cervical Cancer, Genital Wart
Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9
This study will evaluate the immunogenicity and safety of Zerun 9-valent HPV recombinant vaccine in healthy female 16-26 years of age by comparing with GARDASIL®9.
- Conditions
- Cervical Cancer, Genital Wart, CIN, VIN
- Trial name
- NCT05580341
- Testing
- Zerun HPV-9, GARDASIL ®9
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Skin Aging, Wrinkles
Astaxanthin (2 mg) + Lycopene (1.8 mg) + D-Alpha-Tocopherol (10 IU) For The Treatment Of Skin Aging
The purpose of this study is to determine the clinical efficacy of a combination of Astaxanthin (2 mg), Lycopene (1.8 mg), and d-alpha-Tocopherol (10 IU) in terms of its skin anti-aging properties.
- Trial name
- NCT03460860
- Testing
- Astaxanthin (2mg)+Lycopene (1.8mg)+D-Alpha-Tocopherol (10IU)
- Where
- Philippines
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- United Laboratories
Breast Cancer, Gastrointestinal Cancer
A Feasibility Trial of Geriatric Assessment and Management for Older Cancer Patients
The purpose of this study is to determine the feasibility of implementing a randomized controlled study of the intervention (Geriatric Assessment followed by an integrated care plan carried out by the multidisciplinary geriatric…
- Conditions
- Breast Cancer, Gastrointestinal Cancer, Genitourinary Cancer
- Trial name
- NCT02222259
- Testing
- GA and Integrated Care Plan
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Toronto
Skin Aging
Comparison of Redermic, Rejuva-A and Combination of Both Redermic and Rejuva-A in Subjects With Signs of Aging
Facial skin aging is a complex process combining factors such as sun exposure, smoking and those that are believed to be inherited.
- Trial name
- NCT00974480
- Testing
- Redermic, Tretinoin (Rejuva-A)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Breast Cancer
PROACTIVE Study Evaluation of the Impact of a Multidimensional Geriatric Intervention Program
PROACTIVE randomized study to evaluate the impact of a multidimensional geriatric intervention on treatment compliance, measured regularly by blood dosing of drug metabolites.
- Trial name
- PROACTIVE (NCT02216162)
- Testing
- Arm A: adapted physical activity + enhanced geriatric follow-up, No intervention
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer
Study in Elderly Patients With Early Breast Cancer (ICE)
This trial is done to determine the role of adjuvant chemotherapy with capecitabine in patients ≥ 65.
- Trial name
- NCT00196859
- Testing
- Ibandronate, Capecitabine, Ibandronate
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- GBG Forschungs GmbH
Skin Aging, Hair Care
A Pilot Study to Evaluate the Expanded Reach of Decentralized Digital Skin Health Clinical Studies
This is a randomized, decentralized, non-interventional clinical study. The primary objective of this study is to develop execution and efficiency metrics from completion of this study to inform on the potential design for future…
- Conditions
- Skin Aging, Hair Care, Skin Microbiome
- Trial name
- NCT07193290
- Testing
- Lifestyle Questionnaire, Self-portrait image (Face and Hair), Skin microbiome collection
- Where
- United States
- Volunteers
- 1,027 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Androgenetic Alopecia, Androgenic Alopecia
A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Male Subjects With Hair Loss
To demonstrate that the ALRV5XR multi-molecular targeting treatment regimen of a daily shampoo, conditioner, topical serum and oral supplement is superior to placebo in promoting hair growth as assessed by change in hair density…
- Conditions
- Androgenetic Alopecia, Androgenic Alopecia, Telogen Effluvium, Thinning Hair
- Trial name
- REBOOT-MEN (NCT04450589)
- Testing
- ALRV5XR, ALRV5XR Conditioner, ALRV5XR Hair Follicle Serum (Nutriment)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Arbor Life Labs
Skin Aging
Potential of Gayo Arabica Coffee Skin
The purpose of this study was to assess the effectiveness of gayo arabica coffee skin extract cream in the prevention of skin aging
- Trial name
- NCT06940076
- Testing
- gayo arabica coffee skin extract cream
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Wahyu Lestari
Elderly Person, Comfort
Effect of Care Provided Through Skin Care Protocol on Elderly Patients
The rate of elderly population is increasing in the world. It is reported that the proportion of the world population over the age of 60 will increase to 22% by 2050.
- Conditions
- Elderly Person, Comfort, Quality of Life, Skin Moisture
- Trial name
- NCT06462690
- Testing
- pre-mid-post test
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Duygu AKÇA
Skin Aging
Evaluation of the Skin-Beautifying Effects of Collagen Drinks
This study aims to investigate the skin beauty benefits of collagen drinks in healthy individuals.
- Trial name
- NCT06900660
- Testing
- Collagen Drinks
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Simply Plus Co., Ltd.
Aging
Evaluation of Efficacy of Anthelios Sunscreen on Face Versus Usual Routine on Signs of Aging
This experimental, randomized study aims at evaluating the preventative effect of a Sun Protection Factor (SPF) 50+ sunscreen (Anthelios UVMUNE 400 Fluid SPF 50+) with high Ultraviolet A (UVA) protection on clinical signs of skin…
- Trial name
- NCT06697288
- Testing
- Tested product group, Control group
- Where
- Brazil
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Dermatitis, Atopic
Study to Investigate the Efficacy and Safety of Dupilumab Administered With Topical Corticosteroids (TCS) in Participants ≥6 to <12 Years With Severe Atopic Dermatitis (AD)
The main objective of the trial is to demonstrate the efficacy of dupilumab administered concomitantly with topical corticosteroids (TCS) in participants ≥6 years to <12 years of age with severe atopic dermatitis (AD).
- Trial name
- NCT03345914
- Testing
- Dupilumab, Background Treatment: Topical Corticosteroids, Background Treatment: Moisturizers
- Where
- 61 sites in United States, Canada and 4 more
- Volunteers
- 367 people
- Sponsor
- Regeneron Pharmaceuticals